SK Das, SJ Hasstedt, Z Zhang, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc We have identified a region on chromosome 1q21-q24 that was significantly linked to type 2
diabetes in multiplex families of Northern European ancestry and also in Pima Indians, Amish
families, and families from France and England. We sought to narrow and map this locus ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org MCY Ng, WY So, NJ Cox, VKL Lam, CS Cockram, … - Diabetes, 2004 - Am Diabetes Assoc We conducted an autosomal genome scan to map loci for type 2 diabetes in a Hong Kong Chinese
population. We studied 64 families, segregating type 2 diabetes, of which 57 had at least one
member with an age at diagnosis of ≤40 years. These families included a total of 126 ... Cited by 48 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org H Wang, W Chu, SK Das, Q Ren, SJ Hasstedt, SC … - Diabetes, 2002 - Am Diabetes Assoc Pyruvate kinase is a key glycolytic enzyme. Isoforms that are expressed in the red cell, liver, pancreatic
β-cells, small intestine, and proximal renal tubule are encoded by the 12 exons of the PKLR
gene, which maps to chromosome 1q23. We hypothesized that common variants of the ... Cited by 27 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org SK Das, W Chu, Z Zhang, SJ Hasstedt, SC Elbein - Diabetes, 2004 - Am Diabetes Assoc Genome-wide scans in multiple populations have identified chromosome 1q21-q24 as one susceptibility
region for type 2 diabetes. To map the susceptibility genes, we first placed a dense single nucleotide
polymorphism (SNP) map across the linked region. We identified two SNPs that showed ... Cited by 14 - Related articles - BL Direct - All 4 versions
WCHPL St - 糖尿病学杂志, 2003 - journal.shouxi.net We conducted a genome scan using a 10-cM map to search for genes linked to type 2 diabetes
in 691 individuals from a founder population, the Old Order Amish. We then saturated two regions
on chromosomes 1 and 14 showing promising linkage signals with additional markers to ... Cited by 118 - Related articles - Cached - BL Direct - All 3 versions
K Xiang, Y Wang, T Zheng, W Jia, J Li, L Chen, K Shen, … - Diabetes, 2004 - ncbi.nlm.nih.gov This genome-wide search for susceptibility genes to type 2 diabetes/impaired glucose homeostasis
(IGH) was performed on a relatively homogeneous Chinese sample with a total number of 257
pedigrees and 385 affected sibpairs. Two regions showed significant linkage to type 2 ... Cited by 76 - Related articles - BL Direct - All 2 versions
JY Zhao, MM Xiong, W Huang, H Wang, J Zuo, GD … - Journal of Molecular …, 2005 - Springer J Mol Med (2005) 209:209–215 DOI 10.1007/s00109-004-0587-3 ... JY Zhao · MM Xiong ·
W. Huang · H. Wang · J. Zuo · GD Wu · Z. Chen · BQ Qiang · ML Zhang · JL Chen · W. Ding · WT
Yuan · HY Xu · L. Jin · YX Li · Q. Sun · QY Liu · E. Boerwinkle · FD Fang Cited by 26 - Related articles - All 3 versions
- ►diabetesjournals.org M Fu, CM Damcott, M Sabra, TI Pollin, SH Ott, J Wang, … - Diabetes, 2004 - Am Diabetes Assoc Calsequestrin (CASQ)1 is involved in intracellular storage and release of calcium, a process
that has been shown to mediate glucose transport in muscle. Its gene, CASQ1, is encoded on
chromosome 1q21, a region that has been linked to type 2 diabetes in the Amish and ... Cited by 12 - Related articles - BL Direct - All 5 versions
[CITATION] Genome-wide search for type 2 diabetes/impaired glucose homeostasis …
- ►diabetesjournals.org CD Langefeld, LE Wagenknecht, JI Rotter, AH Williams … - Diabetes, 2004 - Am Diabetes Assoc The metabolic syndrome is characterized by central obesity, dyslipidemia, elevated blood
pressure, and hyperglycemia. The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
recruited extended pedigrees of Hispanic descent from San Antonio, TX (SA) and San ... Cited by 60 - Related articles - BL Direct - All 4 versions
