- ►diabetesjournals.org M Gaster, AC Rustan, V Aas, H Beck-Nielsen - Diabetes, 2004 - Am Diabetes Assoc Insulin resistance in skeletal muscle in vivo is associated with reduced lipid oxidation and lipid
accumulation. It is still uncertain whether changes in lipid metabolism represent an adaptive
compensation at the cellular level or a direct expression of a genetic trait. Studies of ... Cited by 52 - Related articles - BL Direct - All 4 versions
M Gaster, H Beck-Nielsen - BBA-Molecular Basis of Disease, 2004 - Elsevier Several defects in response to insulin have been described in vivo and in vitro in type 2
diabetes: a decreased glucose transport, defective glucose oxidation and altered glycogen
synthesis. At present, it is unknown whether glucose oxidation is primarily affected or ... Cited by 14 - Related articles - All 3 versions
M Gaster, SR Kristensen, H Beck-Nielsen, HD … - Apmis, 2001 - interscience.wiley.com The aim of this study was to select an effective and stable protocol for the differentiation of human
satellite cells (Sc) and to identify the optimal time period for the experimental use of differentiated
human Sc-cultures. In order to identify the differentiation conditions which give a good ... Cited by 33 - Related articles - BL Direct - All 4 versions
M Gaster, I Petersen, K Højlund, P Poulsen, H Beck- … - Diabetes, 2002 - Am Diabetes Assoc The most well-described defect in the pathophysiology of type 2 diabetes is reduced insulin-mediated
glycogen synthesis in skeletal muscles. It is unclear whether this defect is primary or acquired
secondary to dyslipidemia, hyperinsulinemia, or hyperglycemia. We determined the ... Cited by 50 - Related articles - BL Direct - All 4 versions
M Gaster, HD Schrøder, A Handberg, H Beck- … - BBA-Molecular Basis of …, 2001 - Elsevier There is no consensus regarding the results from in vivo and in vitro studies on the impact of
chronic high insulin and/or high glucose exposure on acute insulin stimulation of glycogen synthase
(GS) kinetic parameters in human skeletal muscle. The aim of this study was to evaluate ... Cited by 18 - Related articles - All 4 versions
EFC Myotubes - DIABETES, 2004 - Am Diabetes Assoc Insulin resistance in skeletal muscle in vivo is associ- ated with reduced lipid oxidation and lipid
accumula- tion. It is still uncertain whether changes in lipid metabolism represent an adaptive
compensation at the cellular level or a direct expression of a genetic trait. Studies of ... Related articles
N Ørtenblad, M Mogensen, I Petersen, K Højlund, K … - BBA-Molecular Basis of …, 2005 - Elsevier In myotubes established from patients with type 2 diabetes (T2D), lipid oxidation and
insulin-mediated glucose oxidation are reduced, whereas in myotubes from obese non-diabetic
subjects, exposure to palmitate impairs insulin-mediated glucose oxidation. To determine ... Cited by 17 - Related articles - All 3 versions
- ►nih.gov B Ukropcova, M McNeil, O Sereda, L de … - Journal of Clinical …, 2005 - Am Soc Clin Investig Metabolic flexibility of skeletal muscle, that is, the preference for fat oxidation (FOx) during fasting
and for carbohydrate oxidation in response to insulin, is decreased during insulin resistance.
The aim of this study was to test the hypothesis that the capacity of myotubes to oxidize fat ... Cited by 50 - Related articles - BL Direct - All 12 versions
- ►jlr.org [PDF] S Skrede, J Bremer, RK Berge, AC Rustan - The Journal of Lipid Research, 1994 - ASBMB Abstract The present work shows that when mitochondrial 0- oxidation is stimulated by the
hypolipemic, non-0-oxidizable fatty acid analogue tetradecylthioacetic acid, there is a decrease
in the secretion of triacylglycerol in cultured rat hepatocytes. In order to study the effects of ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►jlr.org AJ Wensaas, AC Rustan, K Lovstedt, B Kull, S … - The Journal of Lipid …, 2007 - ASBMB We describe multiwell assays for detecting the accumulation as well as the subsequent oxidation
of 14 C-labeled substrates in cultured cells. Accumulation is monitored in real time by an established
scintillation proximity assay in which the scintillator is embedded in the plate base ... Cited by 8 - Related articles - All 4 versions
