L Kang, VH Routh, EV Kuzhikandathil, LD … - Diabetes, 2004 - Am Diabetes Assoc To evaluate potential mechanisms for neuronal glucosensing, fura-2 Ca 2+ imaging
and single-cell RT-PCR were carried out in dissociated ventromedial hypothalamic
nucleus (VMN) neurons. Glucose-excited (GE) neurons increased and glucose- ... Cited by 94 - Related articles - BL Direct - All 7 versions
AA Dunn-Meynell, VH Routh, L Kang, L … - Diabetes, 2002 - Am Diabetes Assoc Specialized neurons utilize glucose as a signaling molecule to alter their
firing rate. Glucose-excited (GE) neurons increase and glucose-inhibited (GI)
neurons reduce activity as ambient glucose levels rise. Glucose-induced ... Cited by 116 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org R Wang, X Liu, ST Hentges, AA Dunn-Meynell … - Diabetes, 2004 - Am Diabetes Assoc Glucosensing neurons in the hypothalamic arcuate nucleus (ARC) were studied
using electrophysiological and immunocytochemical techniques in neonatal male
Sprague-Dawley rats. We identified glucose-excited and -inhibited neurons, ... Cited by 106 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Z Song, BE Levin, JJ McArdle, N Bakhos, VH … - Diabetes, 2001 - Am Diabetes Assoc Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) were studied
using visually guided slice-patch recording techniques in brain slices from 14-
to 21-day-old male Sprague-Dawley rats. Whole-cell current-clamp recordings ... Cited by 119 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org MG de Vries, LM Arseneau, ME Lawson, JL … - Diabetes, 2003 - Am Diabetes Assoc The activity of neurons in the ventromedial hypothalamus (VMH) important for
initiating compensatory responses to hypoglycemia is influenced by ambient
glucose concentration. In the present study, we used in vivo microdialysis ... Cited by 65 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org Z Song, VH Routh - Diabetes, 2005 - Am Diabetes Assoc Glucose directly alters the action potential frequency of glucosensing neurons
in the ventromedial hypothalamic nucleus (VMN). Glucose-excited neurons
increase, and glucose-inhibited neurons decrease, their action potential ... Cited by 61 - Related articles - All 7 versions
- ►diabetesjournals.org L Kang, AA Dunn-Meynell, VH Routh, LD … - Diabetes, 2006 - Am Diabetes Assoc To test the hypothesis that glucokinase is a critical regulator of neuronal
glucosensing, glucokinase activity was increased, using a glucokinase activator
drug, or decreased, using RNA interference combined with calcium imaging in ... Cited by 49 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org NM Sanders, AA Dunn-Meynell, BE Levin - Diabetes, 2004 - Am Diabetes Assoc Glucokinase (GK) is hypothesized to be the critical glucosensor of pancreatic
β-cells and hypothalamic glucosensing neurons. To understand the role of GK in
glucoprivic counterregulatory responses, we injected alloxan, a GK ... Cited by 36 - Related articles - BL Direct - All 4 versions
BE Levin, VH Routh, L Kang, NM Sanders, … - Diabetes, 2004 - ncbi.nlm.nih.gov Glucosensing neurons are specialized cells that use glucose as a signaling
molecule to alter their action potential frequency in response to variations in
ambient glucose levels. Glucokinase (GK) appears to be the primary ... Cited by 141 - Related articles - BL Direct - All 2 versions
- ►diabetesjournals.org ML Evans, RJ McCrimmon, DE Flanagan, T … - Diabetes, 2004 - Am Diabetes Assoc It has been postulated that specialized glucose-sensing neurons in the
ventromedial hypothalamus (VMH) are able to detect falling blood glucose and
trigger the release of counterregulatory hormones during hypoglycemia. The ... Cited by 74 - Related articles - BL Direct - All 5 versions
