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Scholar Results 1 - 10 of about 101 related to Yan: Expression of voltage-gated potassium channels in human and rhesus pancreatic islets. (0.11 sec) 

Expression of voltage-gated potassium channels in human and rhesus pancreatic …


L Yan, DJ Figueroa, CP Austin, Y Liu, RM Bugianesi, … - Diabetes, 2004 - Am Diabetes Assoc
Voltage-gated potassium channels (Kv channels) are involved in repolarization of excitable cells. In
pancreatic β-cells, prolongation of the action potential by block of delayed rectifier potassium
channels would be expected to ...
Cited by 37 - Related articles - BL Direct - All 4 versions

Inhibition of Kv2. 1 voltage-dependent K+ channels in pancreatic beta-cells …

- jbc.org
PE MacDonald, S Sewing, J Wang, JW Joseph, SR … - Journal of Biological …, 2002 - ASBMB
Voltage-dependent (Kv) outward K + currents repolarize -cell action potentials during a glucose
stimulus to limit Ca 2+ entry and insulin secretion. Dominant-negative "knockout" of Kv2 family
channels enhances ...
Cited by 81 - Related articles - BL Direct - All 4 versions

Biophysical and pharmacological properties of the voltage-gated potassium current …


J Herrington, M Sanchez, D Wunderler, L … - The Journal of …, 2005 - Physiological Soc
Voltage-gated potassium (Kv) currents of human pancreatic islet cells were studied by whole-cell
patch clamp recording. On average, 75% of the cells tested were identified as β-cells by single
cell, post-recording RT-PCR for ...
Cited by 10 - Related articles - BL Direct - All 8 versions

Blockers of the delayed-rectifier potassium current in pancreatic β-cells enhance …

- diabetesjournals.org
J Herrington, YP Zhou, RM Bugianesi, PM Dulski, Y … - Diabetes, 2006 - Am Diabetes Assoc
Delayed-rectifier K + currents (I DR ) in pancreatic β-cells are thought to contribute to action
potential repolarization and thereby modulate insulin secretion. The voltage-gated K + channel, K V
2.1, is expressed in β-cells, and ...
Cited by 27 - Related articles - BL Direct - All 6 versions

Members of the Kv1 and Kv2 voltage-dependent K+ channel families regulate …

- endojournals.org
PE MacDonald, XF Ha, J Wang, SR Smukler, AM … - Molecular …, 2001 - Endocrine Soc
In pancreatic ß-cells, voltage-dependent K + (Kv) channels are potential mediators of
repolarization, closure of Ca 2+ channels, and limitation of insulin secretion. The specific Kv
channels expressed in ß-cells and ...
Cited by 96 - Related articles - BL Direct - All 3 versions

Patch-clamp characterisation of somatostatin-secreting δ-cells in intact mouse …


SO Göpel, T Kanno, S Barg, P Rorsman - The Journal of Physiology, 2000 - Physiological Soc
Three types of electrical activity were observed corresponding to α-, β- and δ-cells. The
δ-cells were electrically active in the presence of glucose but lacked the oscillatory pattern seen
in the β-cells. By contrast, the ...
Cited by 65 - Related articles - All 6 versions

Synaptosome-Associated Protein of 25 Kilodaltons Modulates Kv2. 1 Voltage- …

- endojournals.org
PE MacDonald, G Wang, S Tsuk, C Dodo, Y … - Molecular …, 2002 - Endocrine Soc
Insulin secretion is initiated by ionic events involving membrane depolarization and Ca 2+ entry,
whereas exocytic SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor)
proteins mediate exocytosis itself. ...
Cited by 48 - Related articles - BL Direct - All 3 versions

Delayed-rectifier (KV2. 1) regulation of pancreatic {beta}-cell calcium responses to …

- physiology.org
NA Tamarina, A Kuznetsov, LE Fridlyand, … - American Journal of …, 2005 - Am Physiological Soc
The delayed-rectifier (voltage-activated) K + conductance (K V ) in pancreatic islet -cells has been
proposed to regulate plasma membrane repolarization during responses to glucose, thereby determining
bursting and Ca 2+ oscillations. ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t- …

- aspetjournals.org
T Wolf-Goldberg, I Michaelevski, L Sheu, HY Gaisano, … - Molecular pharmacology, 2006 - ASPET
We have hypothesized that the plasma membrane protein components of the exocytotic soluble
N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complex, syntaxin 1A
and SNAP-25, distinctly regulate ...
Cited by 5 - Related articles - BL Direct - All 5 versions

Delayed rectifying and calcium-activated K+ channels and their significance for …

- rupress.org [PDF] 
PA Smith, K Bokvist, P Arkhammar, PO … - Journal of General …, 1990 - jgp.rupress.org
ABSTRACT The contribution of Ca2+-activated and delayed rectifying K § chan- nels to the
voltage-dependent outward current involved in spike repolarization in mouse pancreatic B-cells
(Rorsman, P., and G. Trube. 1986. ...
Cited by 40 - Related articles - All 3 versions


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