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Scholar Results 1 - 10 of about 101 related to Lechner: No evidence for significant transdifferentiation of bone marrow into pancreatic.... (0.10 sec) 

No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo

- diabetesjournals.org
A Lechner, YG Yang, RA Blacken, L Wang, AL … - Diabetes, 2004 - Am Diabetes Assoc
Several recent studies have suggested that the adult bone marrow harbors cells
that can differentiate into tissues from all three germ layers. Other reports
have contradicted these findings or attributed them to cell fusion. In this ...
Cited by 112 - Related articles - BL Direct - All 4 versions

Little evidence of transdifferentiation of bone marrow-derived cells into pancreatic beta cells


JB Choi, H Uchino, K Azuma, N Iwashita, Y … - Diabetologia, 2003 - Springer
Aims/hypothesis. Bone marrow cells contain at least two distinct types of stem
cells which are haemato- poietic stem cells and mesenchymal stem cells. Both
cells have the ability to differentiate into a variety of cell types ...
Cited by 134 - Related articles - BL Direct - All 3 versions

Failure of transplanted bone marrow cells to adopt a pancreatic β-cell fate

- shouxi.net
J Taneera, A Rosengren, E Renstrom, JM … - Diabetes, 2006 - Am Diabetes Assoc
Recent studies in normal mice have suggested that transplanted bone marrow cells
can transdifferentiate into pancreatic β-cells at relatively high efficiency.
Herein, adopting the same and alternative approaches to deliver and fate ...
Cited by 47 - Related articles - BL Direct - All 5 versions

Recruitment of bone marrow-derived endothelial cells to sites of pancreatic β-cell injury


V Mathews, PT Hanson, E Ford, J Fujita, KS … - Diabetes, 2004 - Am Diabetes Assoc
Endothelial progenitor cells (EPCs) are detectable in the blood and bone marrow
throughout life. These cells contribute to new blood vessel formation
(neovascularization) in physiological states such as wound healing and in ...
Cited by 115 - Related articles - BL Direct - All 4 versions

[PDF] Bone marrow-derived stem cells initiate pancreatic regeneration


D Hess, L Li, M Martin, S Sakano, D Hill, B … - Nature biotechnology, 2003 - users.isr.ist.utl.pt
Bone marrow is an important source of easily procurable adult stem cells1. In
addition to the ability of bone marrow–derived stem cells to reconstitute the
hematopoietic system1, cells derived from the bone marrow compartment have ...
Cited by 329 - Related articles - BL Direct - All 5 versions

Adult bone marrow-derived cells trans-differentiating into insulin-producing cells for the …


SH Oh, TM Muzzonigro, SH Bae, JM LaPlante … - Laboratory Investigation, 2004 - nature.com
Recent findings suggest that bone marrow (BM) cells have the capacity to
differentiate into a variety of cell types including endocrine cells of the
pancreas. We report that BM derived cells, when cultured under defined ...
Cited by 146 - Related articles - BL Direct - All 5 versions

In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without …

- nih.gov
A Ianus, GG Holz, ND Theise, MA Hussain - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
Bone marrow harbors cells that have the capacity to differentiate into cells of
nonhematopoietic tissues of neuronal, endothelial, epithelial, and muscular
phenotype. Here we demonstrate that bone marrow–derived cells populate ...
Cited by 517 - Related articles - BL Direct - All 8 versions

In vivo and in vitro characterization of insulin-producing cells obtained from murine bone …

- tamu-commerce.edu [PDF] 
DQ Tang, LZ Cao, BR Burkhardt, CQ Xia, SA … - Diabetes, 2004 - Am Diabetes Assoc
Efforts toward routine islet cell transplantation as a means for reversing type
1 diabetes have been hampered by islet availability as well as allograft
rejection. In vitro transdifferentiation of mouse bone marrow (BM)-derived ...
Cited by 212 - Related articles - BL Direct - All 7 versions

Reversal of experimental diabetes by multiple bone marrow transplantation


M Banerjee, A Kumar, RR Bhonde - Biochemical and Biophysical Research …, 2005 - Elsevier
Therapeutic utility of bone marrow transplantation in diabetic patients to
overcome deficient β-cell population is an attractive proposal. However, the
status of bone marrow stem cells (BMSCs) under hyperglycemia is not known. ...
Cited by 43 - Related articles - All 5 versions

Islet regeneration during the reversal of autoimmune diabetes in NOD mice

- massgeneral.org [PDF] 
S Kodama, W Kuhtreiber, S Fujimura, EA … - Science, 2003 - sciencemag.org
Nonobese diabetic (NOD) mice are a model for type 1 diabetes in humans.
Treatment of NOD mice with end-stage disease by injection of donor splenocytes
and complete Freund's adjuvant eliminates autoimmunity and permanently ...
Cited by 245 - Related articles - All 12 versions


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