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Scholar Results 1 - 10 of about 101 related to Nobrega: Initial characterization of a rat model of diabetic nephropathy. (0.17 sec) 

Initial characterization of a rat model of diabetic nephropathy


MA Nobrega, S Fleming, RJ Roman, M … - Diabetes, 2004 - Am Diabetes Assoc
The lack of an appropriate animal model that spontaneously develops diabetic
nephropathy has been a significant limitation in the search for genetic factors
underlying this disease and the development of new therapeutic strategies ...
Cited by 20 - Related articles - BL Direct - All 6 versions

[CITATION] Pathogenesis of Glomerular Sclerosis in the Fawn-Hooded Rat


J Simons - Rotterdam, Netherlands: Erasmus University, 1994
Cited by 3 - Related articles

Late onset of diabetic nephropathy in spontaneously diabetic GK rats


N Sato, K Komatsu, H Kurumatani - Am J Nephrol, 2003 - content.karger.com
Background/Aim: Prolonged exposure to hyperglycemia is one of the key factors to
induce progressive diabetic nephropathy in humans. We examined whether or not
the same phenomenon is observed in a nonobese type 2 diabetes model, in ...
Cited by 14 - Related articles - BL Direct - All 5 versions

Clinical pathology in the National Toxicology Program


MB Thompson - Toxicologic Pathology, 1992 - tpx.sagepub.com
The National Toxicology Program (NTP) developed a standard approach for clinical
pathology investigations that was integrated into most toxicity studies designed
and conducted after 1986. Protocols for these studies include specific ...
Cited by 7 - Related articles - BL Direct - All 2 versions

MtDNA point mutations are associated with deletion mutations in aged rat


JW Pak, F Vang, C Johnson, D McKenzie, JM … - Experimental gerontology, 2005 - Elsevier
The age-dependent accumulation of point mutations in the control region of human
mtDNA has been suggested to contribute to aging processes. We investigated
whether mtDNA point mutations accumulate to detectable levels in this ...
Cited by 8 - Related articles - All 3 versions

Interaction between Rf-1 and Rf-4 quantitative trait loci increases susceptibility to renal …


SJ Van Dijk, PAC Specht, MM Lutz, J Lazar, … - Kidney international, 2005 - nature.com
Five quantitative trait loci (QTLs), Rf-1 to Rf-5, were found in Fawn-Hooded
hypertensive (FHH) rats influencing susceptibility to renal damage. Previously,
we found that single transfer of the Rf-1 QTL from FHH rats onto the renal- ...
Cited by 9 - Related articles - BL Direct - All 4 versions

Molecular genetic approaches for studying the etiology of diabetic nephropathy


DPK Ng, AS Krolewski - Current Molecular Medicine, 2005 - ingentaconnect.com
1 Department of Community, Occupational and Family Medicine, and Centre for
Molecular Epidemiology, National University of Singapore 2 Joslin Diabetes
Center, and Department of Medicine, Harvard Medical School, Boston, MA, USA ...
Cited by 22 - Related articles - BL Direct - All 3 versions

Why do mammalian mitochondria possess a mismatch repair activity?


PA Mason, RN Lightowlers - FEBS letters, 2003 - Elsevier
All nucleated mammalian cells contain mitochondrial DNA, a small (approximately
15–17 kb) circular genome found in the matrix. This molecule is present in
multiple copies, with numbers routinely exceeding 1000 per cell. Many ...
Cited by 11 - Related articles - All 5 versions

Myocardial function in rat genetic models of low and high aerobic running capacity

- physiology.org
JC Barbato, SJ Lee, LG Koch, GT Cicila - … Journal of Physiology- Regulatory, Integrative and …, 2002 - Am Physiological Soc
We recently evaluated treadmill aerobic running capacity in 11 inbred strains of
rats and found that isolated working left ventricular function correlated (r =
0.86) with aerobic running capacity. Among these 11 strains the Buffalo ...
Cited by 12 - Related articles - BL Direct - All 6 versions

Pathophysiological, genetic and gene expression features of a novel rodent model of the …


RH Wallis, SC Collins, PJ Kaisaki, K Argoud, … - PLoS One, 2008 - pubmedcentral.nih.gov
We have generated extensive physiological, genetic and genome-wide gene
expression profiles in a congenic strain of the spontaneously diabetic
Goto-Kakizaki (GK) rat containing a large region (110 cM, 170 Mb) of rat ...
Cited by 3 - Related articles - All 7 versions


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