- ►diabetesjournals.org HH Krämer, M Schmelz, F Birklein, A Bickel - Diabetes, 2004 - Am Diabetes Assoc Axon reflex mediated flare depends on the density and the function of cutaneous C-fibers and
may be impaired in diabetic neuropathy. We induced neurogenic axon reflex flare by intracutaneous
electrical stimulation and analyzed size and intensity of the flare on the dorsum of the foot ... Cited by 17 - Related articles - BL Direct - All 4 versions
A Bickel, HH Kramer, MJ Hilz, F Birklein, B Neundorfer, … - Neurology, 2002 - AAN Enterprises Axon reflex flare reaction was studied in 10 patients with neuropathies with small-fiber involvement
(SFN) and in nine healthy volunteers. In each of the 10 patients, SFN was suspected on clinical
and electrophysiological grounds. Nerve conduction studies were performed at the ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org HH Krämer, R Rolke, A Bickel, F Birklein - Diabetes Care, 2004 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Thirty patients with peripheral DN (17 men and 13
women; mean age 52.4 ± 2.5 years) were investigated. Fifteen patients had neuropathic
pain, and 15 patients were free of pain. Patients were followed over 2 years and ... Cited by 26 - Related articles - BL Direct - All 5 versions
B Namer, A Bickel, H Krämer, F Birklein, M … - … Neuroscience: Basic and …, 2004 - Elsevier Both thin afferent (nociceptors) and efferent (sympathetic sudomotor) nerve fibers can be activated
electrically and chemically, resulting in neurogenic erythema and sweating. These reactions
have been used before to assess the impairment of sympathetic and nociceptor fibers in ... Cited by 16 - Related articles - All 8 versions
S Krishnan, G Rayman - Diabetes Care, 2004 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—The neurogenic flare response to nociceptive stimuli
is mediated by an axon reflex involving small unmyelinated C-fibers. We developed a method
to assess this reflex involving skin heating to 44°C to evoke the flare followed by scanning ... Cited by 17 - Related articles - BL Direct - All 5 versions
K Ørstavik, C Mørk, K Kvernebo, E Jørum - Pain, 2004 - Elsevier Twenty-five patients with primary erythromelalgia were examined by neurological testing, neurography
and quantitative sensory testing. Thresholds for heat, cold, heat-pain and cold-pain detection
were compared with those of a group of 29 healthy controls. The patients had significantly ... Cited by 20 - Related articles - All 8 versions
T Schlereth, N Brosda, F Birklein - Neurology, 2005 - AAN Enterprises Methods: In healthy young male subjects, sweat response and flare reaction in response to ACh
were quantified. Constant-current iontophoresis (300 mC) of ACh was performed on the lateral
lower legs. The sudomotor axon reflex was visualized with iodine starch staining, and the ... Cited by 7 - Related articles - All 3 versions
X Navarro, WR Kennedy, TJ Fries - Muscle & Nerve, 1989 - interscience.wiley.com Sensory and autonomic small nerve fiber function was studied in 142 type I diabetics and 45
control subjects. Thermal sensitivity (TS), hot pain sensitivity, and the activity of sweat glands
(SGs) were quantitated on the dorsum of the hand and the foot. TS was abnormal in 86% ... Cited by 34 - Related articles - All 3 versions
D Walmsley, PG Wiles - Journal of Medical Engineering & …, 1990 - informahealthcare.com Pain sensation and neurogenic inflammation are import- ant defence mechanisms subserved
by nociceptor C fibres. Loss of these mechanisms might predispose to disease states such as
diabetic foot ulceration. A quantitative measure of nociceptor C fibre function is therefore ... Cited by 13 - Related articles - All 4 versions
EE Benarroch, PA Low - Annals of neurology, 1991 - interscience.wiley.com We inotophoresed acetylcholine on the dorsum of the foot and simultaneously measured flare
and sweat responses using laser Doppler and sudorometric techniques, respectively. We compared
these responses with those induced by histamine. Both acetylcholine and histamine ... Cited by 27 - Related articles - All 3 versions
