- ►uwo.ca [PDF] RA Kowluru, A Kowluru, S Chakrabarti, Z … - Diabetes, 2004 - Am Diabetes Assoc Hyperglycemia is thought to be the underlying factor in the development of
diabetic retinopathy, but the mechanisms involved remain partially understood.
Diabetes increases oxidative stress, and reactive oxygen species affect the ... Cited by 23 - Related articles - BL Direct - All 7 versions
- ►iovs.org RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Mitochondria and cytosol fractions were prepared from retina of rats
with streptozotocin-induced diabetes and from the isolated retinal endothelial
cells and pericytes incubated in 5 or 20 mM glucose medium for up to 10 ... Cited by 52 - Related articles - BL Direct - All 4 versions
RA Kowluru, P Koppolu - Free Radical Research, 2002 - informahealthcare.com Apoptosis of retinal endothelial cells and pericytes is postulated to contribute
to the development of retinopathy in diabetes. The goal of this study is to
investigate diabetes- induced activation of retinal caspase-3, an apoptosis ... Cited by 60 - Related articles - BL Direct - All 7 versions
RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ... Cited by 75 - Related articles - BL Direct - All 8 versions
ZY Lu, IA Bhutto, T Amemiya - Jpn J Ophthalmol, 2003 - nichigan.or.jp Key Words: Corrosion cast, diabetic retinopathy, electron microscopy, OLETF rat,
spontaneously diabetic animal model. ... Diabetic retinopathy is one of the
most common causes of vision loss. Despite this, to date, no effec- tive ... Cited by 6 - Related articles - All 5 versions
RA Kowluru, A Kowluru, M Kanwar - Molecular and cellular biochemistry, 2007 - Springer We have demonstrated that the expressions of small molecular weight G-protein,
H-Ras, and its effector protein, Raf-1, are increased in the retina in diabetes,
and the specific inhibitors of Ras function inhibit glucose-induced ... Cited by 7 - Related articles - All 4 versions
SH Kim, YK Chu, OW Kwon, SA McCune, FH … - Yonsei Med J, 1998 - eymj.org Soon Hyun Kim, et al. 1988). DM was induced by overloading the polyol pathway
with galactose or sucrose. However, the problems with this method were the
relatively long length of time for disease onset (24 — 36 months) and ... Cited by 7 - Related articles - All 10 versions
[CITATION] Spontaneously diabetic monkeys as a model for diabetic retinopathy
- ►iovs.org PF Kador, Y Takahashi, Y Akagi, H … - Investigative ophthalmology & visual science, 2002 - ARVO PURPOSE. Feeding dogs a diet containing 30% galactose induces experimental
galactosemia and results in the formation of diabetes-like microvascular lesions
of the retina. The appearance and progression of these retinal lesions can ... Cited by 12 - Related articles - BL Direct - All 5 versions
Y Aizu, H Katayama, S Takahama, J Hu, H … - Neuroreport, 2003 - journals.lww.com Intraocular injections of ciliary neurotrophic factor (CNTF) or intraocular
adenovirus-mediated CNTF gene transfer have been reported to inhibit retinal
alterations in inherited retinal degeneration in mice strains. To ... Cited by 12 - Related articles - BL Direct - All 3 versions
