DPK Ng, WH Walker, KS Chia, S Choo, JH … - Diabetes, 2004 - Am Diabetes Assoc Glutamine-fructose-6-phosphate transaminase 1 (GFAT) is the rate-limiting enzyme
of the hexosamine pathway that has been implicated in the pathogenesis of
diabetic nephropathy. As such, we hypothesized that GFPT1, which encodes ... Cited by 9 - Related articles - BL Direct - All 5 versions
SC Elbein, H Zheng, Y Jia, W Chu, JJ Cooper, … - Molecular Genetics and Metabolism, 2004 - Elsevier Increased glucose metabolism through the hexosamine pathway may result in
insulin resistance, impaired insulin secretion, and diabetic nephropathy. We
hypothesized that variants of GFPT1 encoding ... Cited by 7 - Related articles - All 3 versions
- ►endojournals.org C Weigert, C Thamer, K Brodbeck, A Guirguis, … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Increases in glutamine:fructose-6-phosphate aminotransferase (GFAT) protein
levels directly activate flux through the hexosamine biosynthetic pathway. This
pathway has been involved as a fuel sensor in energy metabolism and ... Cited by 10 - Related articles - All 5 versions
D Burt, K Brodbeck, HU Häring, ED Schleicher … - BBA-Molecular Basis of Disease, 2005 - Elsevier Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the rate-limiting
enzyme of the hexosamine biosynthetic pathway (HBP) [1]. The HBP has been
suggested to act as a glucose sensor and mediates decreased insulin ... Cited by 1 - Related articles - All 3 versions
LP Singh, M Alexander, K Greene, ED Crook - Journal of Investigative Medicine, 2003 - journals.lww.com Hyperglycemia-induced alterations in mesangial cell function and extracellular
matrix protein (ECM) accumulation are seen in diabetic glomerulopathy. The
hexosamine biosynthesis pathway (HBP) is implicated in mediating several ... Cited by 7 - Related articles - BL Direct - All 4 versions
M Niimi, T Ogawara, T Yamashita, Y Yamamoto … - Journal of Human Genetics, 2001 - Springer M. Niimi · T. Ogawara · T. Ban · H. Tamanoi · K. Ozaki · T. Fujiwara · E.
Takahashi · H. Kyushiki · A. Tanigami (*) Otsuka GEN Research Institute,
Otsuka Pharmaceutical Co., Ltd., 463-10 Kagasuno, Kawauchi-cho, Tokushima ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►endojournals.org [PDF] HJ Goldberg, CI Whiteside, GW Hart, IG … - Endocrinology, 2005 - Endocrine Soc 1 Department of Medicine, Mount Sinai Hospital and University Health Network; 2
Department of Physiology and 3 Banting and Best Diabetes Centre, University of
Toronto, Toronto, ON, Canada, and the 4 Department of Biological Chemistry, ... Cited by 8 - Related articles
- ►endojournals.org H Zhang, Y Jia, JJ Cooper, T Hale, Z Zhang, … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Increased flux of glucose through the hexosamine biosynthetic pathway has been
implicated in insulin resistance, altered insulin secretion, and diabetic
nephropathy. Glutamine:fructose-6-phosphate amidotransferase (GFPT), the ... Cited by 26 - Related articles - BL Direct - All 4 versions
IG Fantus, HJ Goldberg, CI Whiteside - Springer Catharine. I. Whiteside, MD , P h D , ... C ONTENTS I NTRODUCTION T HE H
EXOSAMINE B IOSYNTHETIC P ATHWAY G LUTAMINE F RUCTOSE 6-P HOSPHATE A
MIDOTRANSFERASE : ... T HE R ATE -L IMITING E NZYME AND D IABETES C ... Related articles
IG Fantus, H MDCM, MD Goldberg, CI … - The Diabetic Kidney, 2006 - books.google.com 7 The Hexosamine Biosynthesis Pathway Contribution to the Pathogenesis of
Diabetic Nephropathy I. George Fantus, MDCM, Howard}. Goldberg, MD, Catharine.
I. Whiteside, MD, PhD, and Delilah Topic, MD CONTENTS INTRODUCTION THE ... Related articles
