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Scholar Results 1 - 10 of about 101 related to Cruzado: Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy.... (0.13 sec) 

Regression of advanced diabetic nephropathy by hepatocyte growth factor gene …

- diabetesjournals.org
JM Cruzado, N Lloberas, J Torras, M Riera, C Fillat, I … - Diabetes, 2004 - Am Diabetes Assoc
Diabetic nephropathy is the main cause of end-stage renal disease requiring dialysis in developed
countries. In this study, we demonstrated the therapeutic effect of hepatocyte growth factor
(HGF) on advanced rather than early diabetic nephropathy using a rat model of ...
Cited by 55 - Related articles - BL Direct - All 4 versions

Suppressions of chronic glomerular injuries and TGF-{beta} 1 production by HGF in …

- physiology.org [PDF] 
S Mizuno, T Nakamura - American Journal of Physiology- Renal …, 2003 - Am Physiological Soc
Page 1. MS no. F-00199-2003.R2 S. Mizuno & T. Nakamura 1 <<Final version for AJP
press>> Title page Title: Suppressions of chronic glomerular injuries and TGF-β1
production by HGF in attenuation of murine diabetic nephropathy ...
Cited by 67 - Related articles - BL Direct - All 5 versions

Intravenous administration of hepatocyte growth factor gene ameliorates diabetic …

- asnjournals.org
C Dai, J Yang, S Bastacky, J Xia, Y Li, Y … - Journal of the American …, 2004 - Am Soc Nephrol
Diabetic nephropathy is characterized by progressive loss of renal function, persistent
proteinuria, and relentless accumulation of extracellular matrix leading to glomerulosclerosis
and interstitial fibrosis. This study investigated the potential effects of long-term ...
Cited by 62 - Related articles - BL Direct - All 5 versions

Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with …


LD DWORKIN, R Gong, E Tolbert, J Centracchio, N … - Kidney international, 2004 - nature.com
The aim of the present study was to examine the effects of HGF on progression of chronic renal
disease in rats with remnant kidneys and established injury. Studies were performed in rats that
underwent subtotal nephrectomy, were observed for two weeks without therapy, and then ...
Cited by 43 - Related articles - BL Direct - All 4 versions

Hepatocyte growth factor counteracts transforming growth factor-β1, through …

- fasebj.org [PDF] 
T Inoue, H Okada, T Kobayashi, Y Watanabe, Y Kanno, … - The FASEB Journal, 2002 - FASEB
*Departments of Nephrology and †Urology, Saitama Medical College, Saitama, Japan; flDepartment
of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine and
Dentistry, Okayama, Japan; §Division of Molecular Regenerative Medicine, Course of ...
Cited by 86 - Related articles - BL Direct - All 3 versions

Hepatocyte growth factor preserves beta cell mass and mitigates hyperglycemia in …


C Dai, Y Li, J Yang, Y Liu - Journal of Biological Chemistry, 2003 - ASBMB
Type I diabetes is an autoimmune disease that results in destructive depletion of the insulin-producing
beta cells in the islets of Langerhans in pancreas. With the knowledge that hepatocyte growth
factor (HGF) is a potent survival factor for a wide variety of cells, we hypothesized that ...
Cited by 47 - Related articles - BL Direct - All 4 versions

Counteractive effects of HGF on PDGF-induced mesangial cell proliferation in a rat …

- physiology.org [PDF] 
K Bessho, S Mizuno, K Matsumoto, T … - American Journal of …, 2003 - Am Physiological Soc
38 articles, 16 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/284/6/F1171#BIBL ... 4 other HighWire hosted articles: This article has been
cited by ... [PDF] [Full Text] [Abstract] , January 1, 2004; 286 (1): F134-F143. Am J Physiol ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Hepatocyte growth factor antagonizes the profibrotic action of TGF-{beta} 1 in …

- asnjournals.org
C Dai, Y Liu - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol
ABSTRACT. Mesangial cell activation is a predominant pathologic feature of diabetic nephropathy
that precedes the accumulation of extracellular matrix leading to glomerulosclerosis. For understanding
the potential mechanism by which hepatocyte growth factor (HGF) ameliorates diabetic ...
Cited by 77 - Related articles - BL Direct - All 8 versions

Hepatocyte growth factor-stimulating endothelial cell growth and accelerating …


T Mori, A Shimizu, Y Masuda, Y Fukuda, N … - Nephron Exp …, 2003 - content.karger.com
Hepatocyte growth factor (HGF) is one of the major growth factors that stimulate the growth and
the migration of vascular endothelial cells. In this study, we examined the beneficial effects of
HGF for glomerular repair in an experimental progressive glomerulonephritis (GN) model ...
Cited by 21 - Related articles - BL Direct - All 5 versions

Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant …

- asnjournals.org
R Gong, A Rifai, EM Tolbert, P Biswas, JN … - Journal of the American …, 2004 - Am Soc Nephrol
Hepatocyte growth factor (HGF) has been shown to reduce renal injury in a variety of animal
models of chronic renal disease. Suggested mechanisms to explain this action include prevention
of tubular cell apoptosis, blocking epithelial-to-mesenchymal transition, and promotion of ...
Cited by 51 - Related articles - BL Direct - All 5 versions


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