- ►diabetesjournals.org LD Love-Gregory, J Wasson, J Ma, CH Jin, B Glaser, … - Diabetes, 2004 - Am Diabetes Assoc Variants in hepatocyte nuclear factor-4α (HNF4α), a transcription factor that influences the
expression of glucose metabolic genes, have been correlated with maturity-onset diabetes of the
young, a monogenic form of ... Cited by 169 - Related articles - BL Direct - All 6 versions
K Silander, KL Mohlke, LJ Scott, EC Peck, P Hollstein, … - Diabetes, 2004 - Am Diabetes Assoc The Finland-United States Investigation Of NIDDM Genetics (FUSION) study aims to identify genetic
variants that predispose to type 2 diabetes by studying affected sibling pair families from Finland.
Chromosome 20 showed our strongest ... Cited by 205 - Related articles - BL Direct - All 10 versions
- ►diabetesjournals.org MN Weedon, KR Owen, B Shields, G Hitman, M Walker … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is part of a transcription factor network that is key for the
development and function of the β-cell. Rare mutations in the HNF4α gene cause maturity-onset
diabetes of the young. A number of ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org CM Damcott, N Hoppman, SH Ott, LJ Reinhart, J Wang, … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor 4-α (HNF4A) is a transcription factor located on chromosome 20q13 that
regulates expression of genes involved in glucose metabolism and homeostasis. Recently, two groups
independently identified single ... Cited by 54 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org W Winckler, RR Graham, PIW de Bakker, M Sun, P … - Diabetes, 2005 - Am Diabetes Assoc Two recent publications reported association of common polymorphisms in the P2 promoter of
hepatocyte nuclear factor 4α (HNF4α) (the MODY1 gene) with risk for type 2 diabetes. We attempted
to reproduce this putative ... Cited by 59 - Related articles - All 8 versions
- ►oxfordjournals.org H Thomas, K Jaschkowitz, M Bulman, TM … - Human molecular …, 2001 - Oxford Univ Press Maturity-onset diabetes of the young (MODY) is a monogenic, autosomal dominant subtype of
early-onset diabetes mellitus due to defective insulin secretion by the pancreatic ß-cell in
humans. Five different genes have ... Cited by 156 - Related articles - BL Direct - All 6 versions
SK Hansen, CS Rose, C Glümer, T Drivsholm, K Borch- … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 452–458 DOI 10.1007/s00125-005-1671-0 ARTICLE SK Hansen .
CS Rose . C. Glümer . T. Drivsholm . K. Borch-Johnsen . T. Jørgensen . O. Pedersen . T.
Hansen Variation near the hepatocyte nuclear factor (HNF)-4α gene ... Cited by 42 - Related articles - All 5 versions
AM Bagwell, JL Bento, JC Mychaleckyj, BI Freedman, … - Diabetes, 2005 - Am Diabetes Assoc Hepatocyte nuclear factor 4α (HNF4A), the gene for the maturity-onset diabetes of the young type 1
monogenic form of type 2 diabetes, is within the type 2 diabetes–linked region on chromosome
20q12-q13.1 and, consequently, is a ... Cited by 32 - Related articles - All 5 versions
- ►diabetesjournals.org YL Muller, AM Infante, RL Hanson, L Love-Gregory, W … - Diabetes, 2005 - Am Diabetes Assoc Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α (HNF4α) gene are
associated with type 2 diabetes in Finns and Ashkenazi Jews. Previous studies in both populations
have reported linkage to type 2 ... Cited by 37 - Related articles - BL Direct - All 6 versions
M Vaxillaire, C Dina, S Lobbens, A Dechaume, V … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 440–444 DOI 10.1007/s00125-004-1665-3 SHORT COMMUNICATION M.
Vaxillaire . C. Dina . S. Lobbens . A. Dechaume . V. Vasseur-Delannoy . N. Helbecque . G.
Charpentier . P. Froguel Effect of common polymorphisms in the HNF4α promoter ... Cited by 27 - Related articles - All 3 versions
