AD Cherrington, DW Neal, DS Edgerton, D Glass, L … - Diabetes, 2004 - Am Diabetes Assoc Pulmonary insulin delivery is being developed as a more acceptable alternative to conventional
subcutaneous administration. In 15 healthy Beagle dogs (average weight 9.3 kg), we compared
insulin distribution in arterial, deep venous, and hepatic portal circulation. Dogs received ... Cited by 8 - Related articles - BL Direct - All 4 versions
DS Edgerton, DW Neal, M Scott, L Bowen, W Wilson, … - Diabetes, 2005 - Am Diabetes Assoc The results of the present study, using the conscious beagle dog, demonstrate that inhaled insulin
(INH; Exubera) provides better glycemic control during an intraportal glucose load than identical
insulin levels induced by insulin (Humulin) infusion into the inferior vena cava (IVC). In ... Cited by 18 - Related articles - All 5 versions
- ►aspetjournals.org DS Edgerton, KM Stettler, DW Neal, M Scott, L … - Journal of Pharmacology …, 2006 - ASPET This study compared the effects of endogenous (portal) insulin secretion versus peripheral insulin
administration with subcutaneous or inhaled human insulin [INH; Exubera, insulin human (rDNA
origin) inhalation powder] on glucose disposal in fasted dogs. In the control group, ... Cited by 3 - Related articles - BL Direct - All 5 versions
S Injection - DIABETES, 2004 - Am Diabetes Assoc Pulmonary insulin delivery is being developed as a more acceptable alternative to conventional
subcutaneous administration. In 15 healthy Beagle dogs (average weight 9.3 kg), we compared
insulin distribution in arterial, deep venous, and hepatic portal circulation. Dogs received ... Related articles
- ►physiology.org P Galassetti, Y Koyama, RH Coker, DB … - American Journal of …, 1999 - Am Physiological Soc Prior exercise stimulates muscle and liver glucose uptake. A negative arterial-portal venous glucose
gradient (a-pv grad) stimulates resting net hepatic glucose uptake (NHGU) but reduces muscle
glucose uptake. This study investigates the effects of a negative a-pv grad during glucose ... Cited by 9 - Related articles - All 3 versions
A Erman, B Chen-Gal, I David, S Giler, G … - … Journal of Clinical & …, 1998 - informahealthcare.com Serum and lung angiotensin-converting enzyme (ACE) activity is increased in the streptozotocin
(STZ)-diabetic rat. In the present study, the effect of insulin treatment on this increased ACE activity
in the STZ-diabetic rat was inves- tigated. Serum and tissue ACE activity was determined ... Cited by 9 - Related articles - BL Direct - All 7 versions
- ►physiology.org CM Donmoyer, SS Chen, SA Hande, DB … - American Journal of …, 2000 - Am Physiological Soc In animals receiving total parenteral nutrition (TPN), infection impairs net hepatic glucose uptake
(NHGU) by 40% and induces mild hyperinsulinemia. In the normal animal, the majority of the
glucose taken up by the liver is diverted to lactate, but in the infected state, lactate release ... Cited by 9 - Related articles - BL Direct - All 3 versions
JH DeVries - Diabetologia, 2005 - Springer To the Editor: Recently, two Phase 3 Exubera inhaled insulin trials in type 1 diabetes and a Phase
2 AERx inhaled insulin trial in type 2 diabetes were reported. No overall difference in HbA 1 c
was noted, but fasting plasma glucose was lower in the inhaled insulin group in all three ... Cited by 5 - Related articles - BL Direct - All 3 versions
LA Distiller, LI Robertson, R Moore, F … - South African medical …, 1987 - ncbi.nlm.nih.gov A trial was undertaken to ascertain the effect and acceptability of a multiple insulin injection regimen
(MII) in patients with insulin-dependent diabetes mellitus using short-acting monocomponent
human soluble insulin (Actrapid HM; Novo) for pre-meal bolus injections with the ... Cited by 5 - Related articles - All 2 versions
AM Sharifi, SH Mousavi, B Larijani - Pharmacological Research, 2004 - Elsevier The precise mechanisms of vascular diseases in patients with insulin-dependent diabetes mellitus
(IDDM) are not clearly understood. There are evidences of alteration in mechanisms involved
in regulating vascular tone including increased ACE activity and decreased NO ... Cited by 6 - Related articles - All 4 versions
