- ►diabetesjournals.org ME Pauza, CM Dobbs, J He, T Patterson, S … - Diabetes, 2004 - Am Diabetes Assoc We have produced a T-cell receptor (TCR) transgenic NOD mouse, 6.9TCR/NOD, in
which the expression of both diabetogenic T-cells and naturally occurring
autoantigen were simultaneously controlled. The parent T-cell clone, ... Cited by 13 - Related articles - BL Direct - All 4 versions
K Haskins - Advances in immunology, 2005 - Elsevier T-cell clones that can efficiently transfer diabetes to prediabetic nonobese
diabetic (NOD) mice provide a powerful approach to dissecting the autoimmune
disease process and for investigating immunoregulation. Diabetogenic T-cell ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org J Cantor, K Haskins - The Journal of Immunology, 2005 - Am Assoc Immnol Effector function of T cells in autoimmune diabetes has been widely studied with
mixed populations of lymphoid T cells stimulated ex vivo, but this approach does
not permit evaluation of the contribution by a single T cell clone in the ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org A Ueno, S Cho, L Cheng, Z Wang, B Wang, Y … - The Journal of Immunology, 2005 - Am Assoc Immnol Polymorphism of MHC and MHC-linked genes is tightly associated with
susceptibility to type 1 diabetes (T1D) in human and animal models. Despite the
extensive studies, however, the role of MHC and MHC-linked genes expressed ... Cited by 3 - Related articles - BL Direct - All 5 versions
K Haskins - Journal of Autoimmunity, 2004 - Elsevier TCR transgenic mice have been of great use to immunologists and have contributed
substantially to our understanding of autoimmune diseases over the last ten
years, as will be evident from this paper and others in this issue. The ... Cited by 5 - Related articles - All 3 versions
BG Dorner, S Steinbach, MB Hüser, RA … - Journal of immunological methods, 2003 - Elsevier Upon stimulation, leukocytes secrete chemokines to attract distinct effector
cell populations to the site of inflammation. Only a few data are available
about the phenotype and the frequencies of cells expressing particular ... Cited by 15 - Related articles - All 5 versions
- ►jimmunol.org DR Tonkin, J He, G Barbour, K Haskins - The Journal of Immunology, 2008 - Am Assoc Immnol Regulatory T cells (Tregs) can potentially be used as tools to suppress
pathogenic T cells in autoimmune diseases such as type 1 diabetes. For use in
therapy it is critically important to determine whether suppression by ... Cited by 6 - Related articles - All 3 versions
JD Peterson, R Berg, JD Piganelli, M Poulin, … - Cellular Immunology, 1998 - Elsevier To investigate host leukocytes recruited to the pancreas by diabetogenic T
cells, we administered islet-specific CD4 + T cell clones to 2-week-old nonobese
diabetic (NOD) mice and examined the resulting pancreatic infiltrate by ... Cited by 8 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org J Cantor, K Haskins - The Journal of Immunology, 2007 - Am Assoc Immnol Adoptive transfer of diabetogenic CD4 Th1 T cell clones into young NOD or
NOD.scid recipients rapidly induces onset of diabetes and also provides a system
for analysis of the pancreatic infiltrate. Although many reports have ... Cited by 9 - Related articles - All 3 versions
PY Arnold, AR Burton, DAA Vignali - The Journal of Immunology, 2004 - Am Assoc Immnol TCR transgenic mice are valuable tools for dissecting the role of
autoantigen-specific T cells in the pathogenesis of type 1 diabetes but are
time-consuming to generate and backcross onto congenic strains. To ... Cited by 21 - Related articles - BL Direct - All 5 versions
