- ►diabetesjournals.org SL McGee, M Hargreaves - Diabetes, 2004 - Am Diabetes Assoc Overexpression of GLUT4 in skeletal muscle enhances whole-body insulin action.
Exercise increases GLUT4 gene and protein expression, and a binding site for the
myocyte enhancer factor 2 (MEF-2) is required on the GLUT4 promoter for ... Cited by 68 - Related articles - BL Direct - All 4 versions
SL McGee, KF Howlett, RL Starkie, D … - Diabetes, 2003 - Am Diabetes Assoc An acute bout of exercise increases skeletal muscle glucose uptake, improves
glucose homeostasis and insulin sensitivity, and enhances muscle oxidative
capacity. Recent studies have shown an association between these ... Cited by 54 - Related articles - BL Direct - All 4 versions
- ►nih.gov AJ Rose, M Hargreaves - The Journal of Physiology, 2003 - Physiological Soc There is evidence in rodents that Ca 2+ -calmodulin-dependent protein kinase II
(CaMKII) activity is higher in contracting skeletal muscle, and this kinase may
regulate skeletal muscle function and metabolism during exercise. To ... Cited by 57 - Related articles - BL Direct - All 6 versions
SL McGee, M Hargreaves - Clinical and Experimental Pharmacology and …, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 25 - Related articles - BL Direct - All 5 versions
JW Ryder, R Bassel-Duby, EN Olson, JR … - Journal of Biological Chemistry, 2003 - ASBMB The protein phosphatase calcineurin is a signaling intermediate that induces the
transformation of fast-twitch skeletal muscle fibers to a slow-twitch phenotype.
This reprogramming of the skeletal muscle gene expression profile may have ... Cited by 63 - Related articles - BL Direct - All 5 versions
SL McGee, M Hargreaves - apps.org.au 1. Skeletal muscle is a highly plastic tissue that has a remarkable ability to
adapt to external demands, such as exercise. Many of these adaptations can be
explained by changes in skeletal muscle gene expression. A single bout of ... Related articles - Cached - All 2 versions
S Mora, JE Pessin - Journal of Biological Chemistry, 2000 - ASBMB Previously, we have demonstrated that an MEF2 consensus sequence located between
−473/−464 in the human GLUT4 gene was essential for both tissue-specific and
hormonal/metabolic regulation of GLUT4 expression (Thai, MV, Guruswamy, S., ... Cited by 65 - Related articles - BL Direct - All 7 versions
- ►pnas.org JB Knight, CA Eyster, BA Griesel, AL Olson - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences The GLUT4 gene is subject to complex tissue-specific and metabolic regulation,
with a profound impact on insulin-mediated glucose disposal. We have shown, by
using transgenic mice, that the human GLUT4 promoter is regulated through ... Cited by 37 - Related articles - BL Direct - All 9 versions
- ►jbc.org MV Thai, S Guruswamy, KT Cao, JE Pessin, … - Journal of Biological Chemistry, 1998 - ASBMB We have previously demonstrated that important regulatory elements responsible
for regulated expression of the human GLUT4 promoter are located between 1154
and 412 relative to transcription initiation (Olson, AL, and Pessin, JE ... Cited by 112 - Related articles - BL Direct - All 4 versions