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Scholar Results 1 - 10 of about 101 related to Sassa: Bifunctional properties of peroxisome proliferator-activated receptor γ1 in KDR gene.... (0.11 sec) 

Bifunctional properties of peroxisome proliferator-activated receptor γ1 in KDR gene …

- diabetesjournals.org
Y Sassa, Y Hata, LP Aiello, Y Taniguchi, K … - Diabetes, 2004 - Am Diabetes Assoc
Vascular endothelial growth factor receptor 2 (KDR) plays a critical role in
mediating a variety of vasculogenic and angiogenic processes, including diabetic
retinopathy. We previously demonstrated that the promoter activity of the ...
Cited by 37 - Related articles - BL Direct - All 5 versions

Peroxisome proliferator-activated receptor-γ ligands as investigational modulators of …


C Giaginis, A Margeli, S Theocharis - Expert Opin. Investig. Drugs, 2007 - informahealthcare.com
PPAR-γ ligands constitute important insulin sensitizers that have already been
approved for the treatment of human metabolic disorders. They also exert
pleiotropic effects on cell proliferation and cancer and are now being ...
Cited by 30 - Related articles - BL Direct - All 8 versions

Antiangiogenic effect of rosiglitazone is mediated via peroxisome proliferator-activated …

- jbc.org
KY Kim, HG Cheon - Journal of Biological Chemistry, 2006 - ASBMB
Recent evidence shows that peroxisome proliferator-activated receptor (PPAR )
ligands induce the antiangiogenic effect in endothelial cells and tumors. In the
present study, we elucidated the involvement of maxi-K channel activation ...
Cited by 16 - Related articles - BL Direct - All 6 versions

Inhibition of corneal neovascularization by a peroxisome proliferator-activated receptor-γ …


MA Sarayba, L Li, T Tungsiripat, NH Liu, PM … - Experimental eye research, 2005 - Elsevier
Methods. Twenty-six adult male Sprague-Dawley rats were randomly divided into
three groups. Each group received intrastromal polymer micropellets containing
one of the following: Group 1, no active ingredient (n=10); Group 2, ...
Cited by 34 - Related articles - All 3 versions

PPAR-{gamma} agonists induce the expression of VEGF and its receptors in cultured cardiac …

- cardiovascres.org
V Chintalgattu, GS Harris, SM Akula, LC … - Cardiovascular Research, 2007 - cardiovascres.org
Objectives: Myofibroblasts (myoFb) are the major cell types that appear at the
site of myocardial infarction (MI) in response to injury and play a vital role
in tissue repair/remodeling. Since vascular endothelial growth factor ...
Cited by 38 - Related articles - All 7 versions

Peroxisome proliferator-activated receptor {gamma} ligands improve the antitumor efficacy …

- aacrjournals.org
H Huang, SC Campbell, DF Bedford, T Nelius, … - Molecular Cancer Research, 2004 - AACR
An expanding capillary network is critical for several pathologic conditions. In
cancer, the decrease of antiangiogenic thrombospondin-1 (TSP1) often enables an
angiogenic switch, which can be reversed with exogenous TSP1 or its peptide ...
Cited by 38 - Related articles - BL Direct - All 3 versions

Inhibition of gastric cancer cells associated angiogenesis by 15d-prostaglandin J2 through …


YG Fu, JJY Sung, KC Wu, AHC Bai, MCW … - Cancer letters, 2006 - Elsevier
Peroxisome proliferator-activated receptor gamma (PPARγ) ligands have been
shown to inhibit angiogenesis. We showed that treatment with 15d-PGJ 2 , a
PPARγ ligand, downregulate the expressions of angiopoietin-1 (Ang-1) in ...
Cited by 11 - Related articles - All 6 versions

[PDF] Ligands of peroxisome proliferator-activated receptor-g increase the generation of vascular …


A Jozkowicz, J Dulak, E Piatkowska, W … - Acta Biochim Pol, 2000 - actabp.pl
Peroxisome proliferator-activated receptors-g (PPARg) are ligand-inducible tran-
scription factors of the nuclear hormone receptor superfamily. We examined the
ef- fect of PPARg activation on the generation of vascular endothelial ...
Cited by 52 - Related articles - View as HTML - BL Direct - All 5 versions

Antiangiogenic therapy with pioglitazone, rofecoxib, and trofosfamide in a patient with …


B Coras, C Hafner, A Reichle, U Hohenleutner … - Archives of Dermatology, 2004 - Am Med Assoc
Observation We describe a 42-year-old dark-skinned patient from Mozambique with
endemic KS. The tumor was first diagnosed 8 years earlier when an ulcerated
nodule appeared at his right ankle joint. Subsequently, multiple reddish ...
Cited by 26 - Related articles - All 4 versions

A consideration of PPAR-γ ligands with respect to lipophilicity: current trends and …


C Giaginis, S Theocharis, A Tsantili- … - Expert Opin. Investig. Drugs, 2007 - informahealthcare.com
The fact that PPAR-γ is expressed dramatically higher in fat, regulating gene
transcription in response to small lipophilic ligands, supports an essential
role of increased lipophilicity for those ligands. On the other hand, the ...
Cited by 7 - Related articles - BL Direct - All 6 versions


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