- ►diabetesjournals.org NM Sanders, AA Dunn-Meynell, BE Levin - Diabetes, 2004 - Am Diabetes Assoc Glucokinase (GK) is hypothesized to be the critical glucosensor of pancreatic β-cells and hypothalamic
glucosensing neurons. To understand the role of GK in glucoprivic counterregulatory
responses, we injected alloxan, a GK inhibitor and toxin, into the third ventricle (3v) to ... Cited by 36 - Related articles - BL Direct - All 4 versions
J Sheffer, A Managing - zlab.rutgers.edu The site contains 1 file. You will need to have Adobe Acrobat? Reader software to read these
files. This is free software and is available for user downloading at http://www.adobe.com/products
/acrobat/readstep.html. ... 1) Reprint Order form 2) A copy of your page proofs for your ... Related articles - View as HTML
- ►nih.gov RJ McCrimmon, Z Song, H Cheng, EC … - Journal of Clinical …, 2006 - Am Soc Clin Investig Recurrent episodes of hypoglycemia impair sympathoadrenal counterregulatory responses
(CRRs) to a subsequent episode of hypoglycemia. For individuals with type 1 diabetes, this markedly
increases (by 25-fold) the risk of severe hypoglycemia and is a major limitation to optimal ... Cited by 29 - Related articles - BL Direct - All 11 versions
NM Sanders, S Ritter - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc A condition of reduced responsiveness to hypoglycemia, known as hypoglycemia-associated
autonomic failure (HAAF), occurs in diabetic patients in the wake of a prior hypoglycemic
episode. This condition suggests that hypoglycemia alters central glucose-sensing ... Cited by 49 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org RJ McCrimmon, ML Evans, X Fan, EC McNay, O Chan, … - Diabetes, 2005 - Am Diabetes Assoc The mechanism(s) by which glucosensing neurons detect fluctuations in glucose remains largely
unknown. In the pancreatic β-cell, ATP-sensitive K + channels (K ATP channels) play a key role
in glucosensing by providing a link between neuronal metabolism and membrane ... Cited by 24 - Related articles - BL Direct - All 6 versions
AA Dunn-Meynell, VH Routh, L Kang, L Gaspers, BE … - Diabetes, 2002 - Am Diabetes Assoc Specialized neurons utilize glucose as a signaling molecule to alter their firing rate.
Glucose-excited (GE) neurons increase and glucose-inhibited (GI) neurons reduce activity as
ambient glucose levels rise. Glucose-induced changes in the ATP-to-ADP ratio in GE ... Cited by 116 - Related articles - BL Direct - All 8 versions
T Minami, N Shimizu, S Duan, Y Oomura - Brain research, 1990 - Elsevier To elucidate the anorectic action of the endogenous organic acid, 3-hydroxybutyric acid
(3-HBA), its effects on neurons in both the rat ventromedial hypothalamic nucleus (VMH) and
the lateral hypothalamic area (LHA) were examined. Iontophoretic application of 3-HBA ... Cited by 17 - Related articles - All 4 versions
NO Tkacs, AA Dunn-Meynell, BE Levin… - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc Hypoglycemia reduces sympathoadrenal responses to subsequent hypoglycemic bouts by an
unknown mecha- nism. To assess whether such hypoglycemia-associated autonomic failure
is due to actual brain damage, male Sprague-Dawley rats underwent 1-h bouts of insulin- ... Cited by 39 - Related articles - BL Direct - All 4 versions
- ►endojournals.org F Maekawa, Y Toyoda, N Torii, I Miwa, RC Thompson, … - Endocrinology, 2000 - Endocrine Soc Pancreatic glucokinase (GK) is considered an important element of the glucose-sensing unit
in pancreatic ß-cells. It is possible that the brain uses similar glucose-sensing units, and we employed
GK immunohistochemistry and confocal microscopy to examine the anatomical ... Cited by 61 - Related articles - BL Direct - All 3 versions
- ►physiology.org R Wang, C Cruciani-Guglielmacci, S … - Journal of …, 2006 - Am Physiological Soc Pharmacological manipulation of fatty acid metabolism in the hypothalamic arcuate nucleus
(ARC) alters energy balance and glucose homeostasis. Thus, we tested the hypotheses that
distinctive populations of ARC neurons are oleic acid (OA) sensors that exhibit a glucose ... Cited by 35 - Related articles - BL Direct - All 4 versions
