- ►diabetesjournals.org AW Cohen, B Razani, W Schubert, TM Williams … - Diabetes, 2004 - Am Diabetes Assoc Recently, it was shown that caveolin-1 can be redirected from the cell surface
to intracellular lipid droplets in a variety of cell types. Here, we directly
address the role of caveolin-1 in lipid droplet formation and breakdown, ... Cited by 92 - Related articles - BL Direct - All 5 versions
- ►physiology.org AW Cohen, B Razani, XB Wang, TP Combs, TM … - American Journal of Physiology- Cell Physiology, 2003 - Am Physiological Soc Several lines of evidence suggest that a functional relationship exists between
caveolin-1 and insulin signaling. However, it remains unknown whether caveolin-1
is normally required for proper insulin receptor signaling in vivo. To ... Cited by 96 - Related articles - BL Direct - All 3 versions
S Le Lay, E Hajduch, MR Lindsay, X Le Liepvre … - Traffic, 2006 - interscience.wiley.com We have investigated the targeting of caveolin to lipid bodies in adipocytes
that express high levels of caveolins and contain well-developed lipid droplets.
We observed that the lipid droplets isolated from adipocytes of caveolin-1 ... Cited by 36 - Related articles - BL Direct - All 4 versions
- ►rupress.org AG Ostermeyer, JM Paci, Y Zeng, DM Lublin, … - Journal of Cell Biology, 2001 - jcb.rupress.org Caveolin-1 is normally localized in plasma membrane caveolae and the Golgi
apparatus in mammalian cells. We found three treatments that redirected the
protein to lipid storage droplets, identified by staining with the ... Cited by 153 - Related articles - BL Direct - All 9 versions
B Razani, TP Combs, XB Wang, PG Frank, DS … - Journal of Biological Chemistry, 2002 - ASBMB Caveolae organelles and caveolin-1 protein expression are most abundant in
adipocytes and endothelial cells. Our initial report on mice lacking caveolin-1
(Cav-1) demonstrated a loss of caveolae and perturbations in endothelial ... Cited by 224 - Related articles - BL Direct - All 5 versions
- ►jbc.org A Ost, U Ortegren, J Gustavsson, FH Nystrom, … - Journal of Biological Chemistry, 2005 - ASBMB A principal metabolic function of adipocytes is to synthesize triacylglycerol
(TG) from exogenous fatty acids. The level of fatty acids has to be tightly
controlled in the adipocyte, as they can act as detergents that rapidly ... Cited by 47 - Related articles - All 6 versions
- ►molbiolcell.org A Pol, S Martin, MA Fernandez, C Ferguson, A … - Molecular biology of the cell, 2004 - Am Soc Cell Biol Caveolins are a crucial component of caveolae but have also been localized to
the Golgi complex, and, under some experimental conditions, to lipid bodies
(LBs). The physiological relevance and dynamics of LB association remain ... Cited by 85 - Related articles - BL Direct - All 7 versions
P Liu, Y Ying, Y Zhao, DI Mundy, M Zhu, … - Journal of Biological Chemistry, 2004 - ASBMB The principal lipids in animal cell lipid droplets are cholesterol, cholesterol
ester, and triglyceride, but the protein composition of this compartment is
largely unknown. Here we report on the proteomic analysis of lipid ... Cited by 214 - Related articles - BL Direct - All 4 versions
DL Brasaemle, G Dolios, L Shapiro, R Wang - Journal of Biological Chemistry, 2004 - ASBMB Adipocytes hold the body's major energy reserve as triacylglycerols packaged in
large lipid droplets. Perilipins, the most abundant proteins on these lipid
droplets, play a critical role in facilitating both triacylglycerol storage ... Cited by 229 - Related articles - BL Direct - All 3 versions
- ►rupress.org C Sztalryd, G Xu, H Dorward, JT Tansey, JA … - Journal of Cell Biology, 2003 - jcb.rupress.org Akey step in lipolytic activation of adipocytes is the translocation of
hormone-sensitive lipase (HSL) from the cytosol to the surface of the lipid
storage droplet. Adipocytes from perilipin-null animals have an elevated ... Cited by 199 - Related articles - BL Direct - All 11 versions
