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Scholar Results 1 - 10 of about 101 related to Curat: From Blood Monocytes to Adipose Tissue-Resident Macrophages. (0.15 sec) 

From Blood Monocytes to Adipose Tissue-Resident Macrophages


CA Curat, A Miranville, C Sengenès, M Diehl, C Tonus, … - Diabetes, 2004 - Am Diabetes Assoc
Obesity has been suggested to be a low-grade systemic inflammatory state, therefore we studied
the interaction between human adipocytes and monocytes via adipose tissue (AT)-derived capillary
endothelium. Cells composing the stroma-vascular fraction (SVF) of human ATs were ...
Cited by 218 - Related articles - BL Direct - All 4 versions

Reduction of macrophage infiltration and chemoattractant gene expression …


R Cancello, C Henegar, N Viguerie, S Taleb, C Poitou, … - Diabetes, 2005 - Am Diabetes Assoc
In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is enriched
in macrophages. These cells may contribute to low-grade inflammation and to its metabolic
complications. Little is known about the effect of weight loss on macrophages and genes ...
Cited by 251 - Related articles - BL Direct - All 5 versions

Weight loss regulates inflammation-related genes in white adipose tissue of obese …

- fasebj.org
K Clement, N Viguerie, C Poitou, C Carette, V Pelloux, … - The FASEB Journal, 2004 - FASEB
Adipose tissue produces inflammation and immunity molecules suspected to be involved in
obesity-related complications. The pattern of expression and the nutritional regulation of these
molecules in humans are poorly understood. We analyzed the gene expression profiles ...
Cited by 215 - Related articles - BL Direct - All 8 versions

Preadipocyte conversion to macrophage


G Charriere, B Cousin, E Arnaud, M Andre, F Bacou … - Journal of Biological …, 2003 - ASBMB
Preadipocytes are present throughout adult life in adipose tissues and can proliferate and differentiate
into mature adipocytes according to the energy balance. An increasing number of reports demonstrate
that cells from adipose lineages (preadipocytes and adipocytes) and macrophages share ...
Cited by 236 - Related articles - BL Direct - All 4 versions

Macrophage-secreted factors induce adipocyte inflammation and insulin resistance


PA Permana, C Menge, PD Reaven - Biochemical and biophysical research …, 2006 - Elsevier
Macrophage infiltration into adipose tissue increases with obesity, a condition associated with
low-grade inflammation and insulin resistance. We investigated the direct effects of
macrophage-secreted factors on adipocyte inflammation and insulin resistance. 3T3-L1 ...
Cited by 106 - Related articles - All 5 versions

Adipocyte death defines macrophage localization and function in adipose tissue of …

- jlr.org
S Cinti, G Mitchell, G Barbatelli, I Murano, E Ceresi, … - The Journal of Lipid …, 2005 - ASBMB
Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications
of obesity. The precipitating event(s) and function(s) of macrophage infiltration into WAT are
unknown. We demonstrate that >90% of all macrophages in WAT of obese mice and ...
Cited by 288 - Related articles - BL Direct - All 8 versions

Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated …


T Christiansen, B Richelsen, JM Bruun - International Journal of Obesity, 2004 - nature.com
(1) To compare mRNA levels of MCP-1, leptin and a macrophage-specific marker (CD68) in
isolated adipocytes vs stromal–vascular (SV) cells, (2) to compare mRNA levels of MCP-1 in
human adipose tissue to circulating MCP-1 and adiposity (eg BMI: kg/m 2 ) and (3) ...
Cited by 144 - Related articles - All 5 versions

Macrophages in human visceral adipose tissue: increased accumulation in obesity …


CA Curat, V Wegner, C Sengenes, A Miranville, C … - Diabetologia, 2006 - Springer
Abstract Aims/hypothesis: Increased visceral white adipose tissue (WAT) is linked to the risk
of developing diabetes. Methods/results: We showed by fluorescence activated cell sorting analysis
that human visceral WAT contains macrophages, the proportion of which increased with ...
Cited by 203 - Related articles - BL Direct - All 3 versions

Increased infiltration of macrophages in omental adipose tissue is associated with …


R Cancello, J Tordjman, C Poitou, G Guilhem, JL … - Diabetes, 2006 - Am Diabetes Assoc
In human obesity, white adipose tissue (WAT) is enriched in macrophages. How macrophage
infiltration in WAT contributes to the complications of obesity is unknown. This study tested the
hypothesis that recruitment of macrophages in omental WAT is associated with hepatic ...
Cited by 112 - Related articles - BL Direct - All 5 versions

Chronic inflammation in fat plays a crucial role in the development of obesity- …

- nih.gov
H Xu, GT Barnes, Q Yang, G Tan, D Yang, … - Journal of Clinical …, 2003 - Am Soc Clin Investig
Insulin resistance arises from the inability of insulin to act normally in regulating nutrient metabolism
in peripheral tissues. Increasing evidence from human population studies and animal research
has established correlative as well as causative links between chronic inflammation and ...
Cited by 1336 - Related articles - BL Direct - All 14 versions


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