QS Mi, D Ly, P Zucker, M McGarry, TL … - Diabetes, 2004 - Am Diabetes Assoc In nonobese diabetic (NOD) mice, a deficiency in the number and function of
invariant natural killer T-cells (iNKT cells) contributes to the onset of type 1
diabetes. The activation of CD1d-restricted iNKT cells by ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org J Novak, L Beaudoin, T Griseri, A Lehuen - The Journal of Immunology, 2005 - Am Assoc Immnol NKT cells are potent regulatory T cells that prevent the development of several
autoimmune diseases. Analysis of NKT cell regulatory function in the NOD mouse
has revealed that NKT cells inhibit the development of type 1 diabetes by ... Cited by 29 - Related articles - All 5 versions
- ►jimmunol.org D Ly, QS Mi, S Hussain, TL Delovitch - The Journal of Immunology, 2006 - Am Assoc Immnol Invariant NK T (iNKT) cells regulate immune responses, express NK cell markers
and an invariant TCR, and recognize lipid Ags in a CD1d-restricted manner.
Previously, we reported that activation of iNKT cells by ... Cited by 29 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org M Falcone, F Facciotti, N Ghidoli, P Monti, S … - The Journal of Immunology, 2004 - Am Assoc Immnol The immunoregulatory function of NKT cells is crucial for prevention of
autoimmunity. The prototypical NKT cell Ag -galactosylceramide is not present in
mammalian cells, and little is known about the mechanism responsible for ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org MJD Wagner, S Hussain, M Mehan, JM Verdi, … - The Journal of Immunology, 2005 - Am Assoc Immnol A numerical and functional deficiency in invariant NKT (iNKT) cells detectable
by 3 wk of age in the thymus and spleen mediates the pathogenesis of type 1
diabetes in NOD mice, but the stage of T cell development at which this ... Cited by 10 - Related articles - All 5 versions
- ►jimmunol.org YG Chen, CM Choisy-Rossi, TM Holl, HD … - The Journal of Immunology, 2005 - Am Assoc Immnol NKT cell activation by -galactosylceramide ( -GalCer) inhibits autoimmune
diabetes in NOD mice, in part by inducing recruitment to pancreatic lymph nodes
(PLNs) of mature dendritic cells (DCs) with disease-protective effects. ... Cited by 66 - Related articles - All 5 versions
A Rocha-Campos, R Melki, R Zhu, N Deruytter … - DIABETES-NEW YORK-, 2006 - 万方数据资源系统 Defective invariant natural killer T-cells (iNKT cells) have been implicated in
the etiology of type 1 diabetes in nonobese diabetic (NOD) mice. In a genome
scan of a cross between NOD and C57BL/6 mice, the most significant locus ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org LM Esteban, T Tsoutsman, MA Jordan, D Roach … - The Journal of Immunology, 2003 - Am Assoc Immnol Natural killer T cells are an immunoregulatory population of lymphocytes that
plays a critical role in controlling the adaptive immune system and contributes
to the regulation of autoimmune responses. We have previously reported ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org Y Oikawa, A Shimada, S Yamada, Y Motohashi … - Diabetes care, 2002 - Am Diabetes Assoc OBJECTIVE—Natural killer T-cells (NKT cells) are believed to play an important
role in the regulation of immune response, and a numerical and functional
deficit of NKT cells has been reported to be associated with the ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org SC Kent, Y Chen, SM Clemmings, V Viglietta, … - The Journal of Immunology, 2005 - Am Assoc Immnol Altered frequency and function of peripheral invariant NKT (iNKT) cells have
been implicated in the regulation of murine and human type 1a diabetes. To
examine regulatory cells from the site of drainage of autoinflammatory ... Cited by 20 - Related articles - BL Direct - All 4 versions
