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Scholar Results 1 - 10 of about 101 related to Ohsugi: Glucose and insulin treatment of insulinoma cells results in transcriptional regulation.... (0.14 sec) 

Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a …

- diabetesjournals.org
M Ohsugi, C Cras-Méneur, Y Zhou, W Warren, … - Diabetes, 2004 - Am Diabetes Assoc
Glucose and insulin are important regulators of islet ß-cell growth and
function by activating signaling pathways resulting in transcriptional changes
that lead to adaptive responses. Several immediate early genes have been ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Glucose induces early growth response gene (Egr-1) expression in pancreatic beta cells


K Josefsen, LR Sørensen, K Buschard, M … - Diabetologia, 1999 - Springer
Glucose homeostasis is maintained by beta cells of pancreatic islets through
precisely regulated release of insulin from preformed granules. To maintain con-
stant intracellular insulin stores while meeting wide physiological ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Activation of serum response factor in the depolarization induction of Egr-1 transcription in …


E Bernal-Mizrachi, B Wice, H Inoue, MA … - Journal of Biological Chemistry, 2000 - ASBMB
The results of the current studies define the major elements whereby glucose
metabolism in islet β-cells leads to transcriptional activation of an early
response gene in insulinoma cell lines and in rat islets. Glucose ...
Cited by 45 - Related articles - BL Direct - All 7 versions

Regulation of insulin gene transcription by the immediate-early growth response gene Egr-1


K Eto, V Kaur, MK Thomas - Endocrinology, 2006 - Endocrine Soc
Changes in extracellular glucose levels regulate the expression of the
immediate-early response gene and zinc finger transcription factor early growth
response-1 (Egr-1) in insulin-producing pancreatic ß-cells, but key target ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase

- jbc.org
BS Finlin, RN Correll, C Pang, SM Crump, J … - Journal of Biological Chemistry, 2006 - ASBMB
Voltage-gated calcium channels are multiprotein complexes that regulate calcium
influx and are important contributors to cardiac excitability and contractility.
The auxiliary -subunit (Ca V ) binds a conserved domain (the -interaction ...
Cited by 20 - Related articles - BL Direct - All 4 versions

[PDF] Reduced Expression of the Insulin Receptor in Mouse Insulinoma(MIN 6) Cells Reveals …


M Ohsugi, C Cras-Meneur, Y Zhou, E Bernal- … - Journal of Biological Chemistry, 2005 - ASBMB
Running Title: Multiple roles of insulin signaling in islet cells ... Reduced
Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals
Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, ...
Cited by 39 - Related articles - All 5 versions

Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase

- jbc.org
BS Finlin, AL Mosley, SM Crump, RN Correll, … - Journal of Biological Chemistry, 2005 - ASBMB
Voltage-dependent calcium (Ca 2+ ) channels are involved in many specialized
cellular functions and are controlled by a diversity of intracellular signals.
Recently, members of the RGK family of small GTPases (Rem, Rem2, Rad, ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Dose-dependent and Isoform-specific Modulation of Ca2+ Channels by RGK GTPases

- rupress.org
L Seu, GS Pitt - Journal of General Physiology, 2006 - jgp.rupress.org
Although inhibition of voltage-gated calcium channels by RGK GTPases (RGKs)
represents an important mode of regulation to control Ca 2+ influx in excitable
cells, their exact mechanism of inhibition remains controversial. This has ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization …

- nih.gov
Y Ward, B Spinelli, MJ Quon, H Chen, SR … - Molecular and Cellular Biology, 2004 - Am Soc Microbiol
Gem is a small GTP-binding protein that has a ras-like core and extended chains
at each terminus. The primary structure of Gem and other RGK family members
(Rad, Rem, and Rem2) predicts a GTPase deficiency, leading to the question ...
Cited by 41 - Related articles - BL Direct - All 9 versions

Expression of Rem2, an RGK family small GTPase, reduces N-type calcium current without …

- cjb.net
H Chen, HL Puhl III, SL Niu, DC Mitchell, SR … - Journal of Neuroscience, 2005 - neuro.cjb.net
Rad, Gem/Kir, Rem, and Rem2 are members of the Ras-related RGK (Rad, Gem, and
Kir) family of small GTP-binding proteins. Heterologous expression of RGK
proteins interferes with de novo calcium channel assembly/trafficking and ...
Cited by 30 - Related articles - BL Direct - All 6 versions


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