- ►diabetesjournals.org M Ohsugi, C Cras-Méneur, Y Zhou, W Warren, … - Diabetes, 2004 - Am Diabetes Assoc Glucose and insulin are important regulators of islet ß-cell growth and
function by activating signaling pathways resulting in transcriptional changes
that lead to adaptive responses. Several immediate early genes have been ... Cited by 32 - Related articles - BL Direct - All 4 versions
K Josefsen, LR Sørensen, K Buschard, M … - Diabetologia, 1999 - Springer Glucose homeostasis is maintained by beta cells of pancreatic islets through
precisely regulated release of insulin from preformed granules. To maintain con-
stant intracellular insulin stores while meeting wide physiological ... Cited by 31 - Related articles - BL Direct - All 4 versions
E Bernal-Mizrachi, B Wice, H Inoue, MA … - Journal of Biological Chemistry, 2000 - ASBMB The results of the current studies define the major elements whereby glucose
metabolism in islet β-cells leads to transcriptional activation of an early
response gene in insulinoma cell lines and in rat islets. Glucose ... Cited by 45 - Related articles - BL Direct - All 7 versions
K Eto, V Kaur, MK Thomas - Endocrinology, 2006 - Endocrine Soc Changes in extracellular glucose levels regulate the expression of the
immediate-early response gene and zinc finger transcription factor early growth
response-1 (Egr-1) in insulin-producing pancreatic ß-cells, but key target ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►jbc.org BS Finlin, RN Correll, C Pang, SM Crump, J … - Journal of Biological Chemistry, 2006 - ASBMB Voltage-gated calcium channels are multiprotein complexes that regulate calcium
influx and are important contributors to cardiac excitability and contractility.
The auxiliary -subunit (Ca V ) binds a conserved domain (the -interaction ... Cited by 20 - Related articles - BL Direct - All 4 versions
M Ohsugi, C Cras-Meneur, Y Zhou, E Bernal- … - Journal of Biological Chemistry, 2005 - ASBMB Running Title: Multiple roles of insulin signaling in islet cells ... Reduced
Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals
Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, ... Cited by 39 - Related articles - All 5 versions
- ►jbc.org BS Finlin, AL Mosley, SM Crump, RN Correll, … - Journal of Biological Chemistry, 2005 - ASBMB Voltage-dependent calcium (Ca 2+ ) channels are involved in many specialized
cellular functions and are controlled by a diversity of intracellular signals.
Recently, members of the RGK family of small GTPases (Rem, Rem2, Rad, ... Cited by 39 - Related articles - BL Direct - All 5 versions
- ►rupress.org L Seu, GS Pitt - Journal of General Physiology, 2006 - jgp.rupress.org Although inhibition of voltage-gated calcium channels by RGK GTPases (RGKs)
represents an important mode of regulation to control Ca 2+ influx in excitable
cells, their exact mechanism of inhibition remains controversial. This has ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►nih.gov Y Ward, B Spinelli, MJ Quon, H Chen, SR … - Molecular and Cellular Biology, 2004 - Am Soc Microbiol Gem is a small GTP-binding protein that has a ras-like core and extended chains
at each terminus. The primary structure of Gem and other RGK family members
(Rad, Rem, and Rem2) predicts a GTPase deficiency, leading to the question ... Cited by 41 - Related articles - BL Direct - All 9 versions
- ►cjb.net H Chen, HL Puhl III, SL Niu, DC Mitchell, SR … - Journal of Neuroscience, 2005 - neuro.cjb.net Rad, Gem/Kir, Rem, and Rem2 are members of the Ras-related RGK (Rad, Gem, and
Kir) family of small GTP-binding proteins. Heterologous expression of RGK
proteins interferes with de novo calcium channel assembly/trafficking and ... Cited by 30 - Related articles - BL Direct - All 6 versions