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Scholar Results 1 - 10 of about 101 related to Tonelli: Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes. (0.10 sec) 

Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes

- diabetesjournals.org
J Tonelli, W Li, P Kishore, UB Pajvani, E … - Diabetes, 2004 - Am Diabetes Assoc
Whereas thiazolidinediones (TZDs) are known to rapidly improve insulin action in
animals, short durations of TZD therapy have never been studied in humans. Among
the many known actions of TZDs, increased circulating levels of the high ...
Cited by 143 - Related articles - BL Direct - All 5 versions

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione- …


UB Pajvani, M Hawkins, TP Combs, MW Rajala … - Journal of Biological Chemistry, 2004 - ASBMB
Adiponectin is an adipocyte-specific secretory protein that circulates in serum
as a hexamer of relatively low molecular weight (LMW) and a larger multimeric
structure of high molecular weight (HMW). Serum levels of the protein ...
Cited by 533 - Related articles - BL Direct - All 5 versions

Serum high molecular weight complex of adiponectin correlates better with glucose …


M Fisher, ME Trujillo, W Hanif, AH Barnett, … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: It is well established that total systemic adiponectin
is reduced in type 2 diabetic subjects. To date most studies have been concerned
with the singular full-length protein or proteolytically cleaved globular ...
Cited by 124 - Related articles - All 3 versions

Impaired multimerization of human adiponectin mutants associated with diabetes


H Waki, T Yamauchi, J Kamon, Y Ito, S Uchida … - Journal of Biological Chemistry, 2003 - ASBMB
Adiponectin is an adipocyte-derived hormone, which has been shown to play
important roles in the regulation of glucose and lipid metabolism. Eight
mutations in human adiponectin have been reported, some of which were ...
Cited by 423 - Related articles - BL Direct - All 4 versions

Changes of adiponectin oligomer composition by moderate weight reduction

- angrylapdog.com
T Bobbert, H Rochlitz, U Wegewitz, S Akpulat, … - Diabetes, 2005 - diabetes.diabetesjournals.org.p.angrylapdog.com
Adiponectin affects lipid metabolism and insulin sensitivity. However,
adiponectin circulates in three different oligomers that may also have distinct
biological functions. We aimed to analyze the role of these oligomers in ...
Cited by 140 - Related articles - BL Direct - All 8 versions

Measurement of the high–molecular weight form of adiponectin in plasma is useful for the …

- diabetesjournals.org
K Hara, M Horikoshi, T Yamauchi, H Yago, O … - Diabetes Care, 2006 - Am Diabetes Assoc
OBJECTIVE—The high–molecular weight (HMW) form of adiponectin, an
adipocyte-derived insulin-sensitizing hormone, has been reported to be the most
active form of this hormone. We investigated whether measurement of plasma ...
Cited by 147 - Related articles - BL Direct - All 5 versions

Pioglitazone increases secretion of high molecular weight adiponectin from adipocytes

- physiology.org [PDF] 
A Bodles, A Banga, N Rasouli, F Ono, PA … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
The Central Arkansas Veterans Healthcare System, and the Department of Medicine,
Division of Endocrinology, University of Arkansas for Medical Sciences, Little
Rock, Arkansas 72205 † Both authors contributed equally.
Cited by 64 - Related articles - BL Direct - All 3 versions

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin


UB Pajvani, X Du, TP Combs, AH Berg, MW … - Journal of Biological Chemistry, 2003 - ASBMB
Acrp30/adiponectin is an adipocyte-specific secretory protein that has recently
been implicated as a mediator of systemic insulin sensitivity with liver and
muscle as target organs. Acrp30 is found as two forms in serum, as a lower ...
Cited by 505 - Related articles - BL Direct - All 4 versions

Adiponectin multimeric complexes and the metabolic syndrome trait cluster

- diabetesjournals.org
C Lara-Castro, N Luo, P Wallace, RL Klein, … - Diabetes, 2006 - Am Diabetes Assoc
Adiponectin circulates in human plasma mainly as a 180-kDa low molecular weight
(LMW) hexamer and a high molecular weight (HMW) multimer of ∼360 kDa. We
comprehensively examined the relationships between circulating levels of ...
Cited by 179 - Related articles - BL Direct - All 5 versions

Effect of pioglitazone on circulating adipocytokine levels and insulin sensitivity in type 2 …

- endojournals.org
Y Miyazaki, A Mahankali, E Wajcberg, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
We examined the effect of pioglitazone (PIO) on circulating adipocytokine levels
to elucidate the mechanisms by which thiazolidinediones improve insulin
resistance in type 2 diabetes mellitus (T2DM). Twenty-three subjects with ...
Cited by 115 - Related articles - BL Direct - All 5 versions


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