- ►diabetesjournals.org SLM Coort, DM Hasselbaink, DPY Koonen, J Willems, … - Diabetes, 2004 - Am Diabetes Assoc In obesity, the development of cardiomyopathy is associated with the accumulation of myocardial
triacylglycerols (TAGs), possibly stemming from elevation of myocardial long-chain fatty acid
(LCFA) uptake. Because LCFA uptake is regulated by insulin and contractions, we ... Cited by 64 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org JJFP Luiken, DPY Koonen, J Willems, A Zorzano, C … - Diabetes, 2002 - Am Diabetes Assoc The existence of an intracellular pool of fatty acid translocase (FAT/CD36), an 88-kDa membrane
transporter for long-chain fatty acids (FAs), and the ability of insulin to induce translocation events
prompted us to investigate the direct effects of insulin on cellular uptake of FA by the ... Cited by 93 - Related articles - BL Direct - All 6 versions
A Chabowski, SLM Coort, J Calles-Escandon, NN … - FEBS letters, 2005 - Elsevier Cellular fatty acid uptake is facilitated by a number of fatty acid transporters, FAT/CD36, FABPpm
and FATP1. It had been presumed that FABPpm, was confined to the plasma membrane and
was not regulated. Here, we demonstrate for the first time that FABPpm and FATP1 are ... Cited by 50 - Related articles - All 7 versions
JJFP Luiken, Y Arumugam, DJ Dyck, RC Bell, MML … - Journal of Biological …, 2001 - ASBMB Giant vesicles were used to study the rates of uptake of long-chain fatty acids by heart, skeletal
muscle, and adipose tissue of obese and lean Zucker rats. With obesity there was an increase
in vesicular fatty acid uptake of 1.8-fold in heart, muscle and adipose tissue. In some ... Cited by 133 - Related articles - BL Direct - All 4 versions
AN Carley, DL Severson - BBA-Molecular and Cell Biology of Lipids, 2005 - Elsevier The metabolic phenotype of hearts has been investigated using rodent models of type 2 diabetes
which exhibit obesity and insulin resistance: db/db and ob/ob mice, and Zucker fatty and ZDF
rats. In general, cardiac fatty acid (FA) utilization is enhanced in type 2 diabetic hearts, ... Cited by 73 - Related articles - All 3 versions
- ►sc.edu [PDF] DPY Koonen, JFC Glatz, A Bonen, JJFP Luiken - BBA-Molecular and Cell …, 2005 - Elsevier Cellular long-chain fatty acid (LCFA) uptake constitutes a process that is not yet fully
understood. LCFA uptake likely involves both passive diffusion and protein-mediated
transport. Several lines of evidence support the involvement of a number of plasma ... Cited by 83 - Related articles - All 4 versions
JJFP Luiken, SLM Coort, DPY Koonen, DJ Horst, A … - Pflügers Archiv European …, 2004 - Springer Page 1. Pflugers Arch - Eur J Physiol (2004) 448: 1–15 DOI 10.1007/s00424-003-1199-
4 INVITED REVIEW Joost JFP Luiken . Susan LM Coort . Debby PY Koonen . Dick J.
van der Horst . Arend Bonen . Antonio Zorzano . Jan FC Glatz ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►physiology.org A Chabowski, SLM Coort, J Calles- … - American Journal of …, 2004 - Am Physiological Soc Because insulin has been shown to stimulate long-chain fatty acid (LCFA) esterification in skeletal
muscle and cardiac myocytes, we investigated whether insulin increased the rate of LCFA transport
by altering the expression and the subcellular distribution of the fatty acid transporters ... Cited by 40 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] A Bonen, ML Parolin, GR Steinberg, J Calles- … - The FASEB Journal, 2004 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.03-1065fje. Published online May 7, 2004.
Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased
rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36 ... Cited by 132 - Related articles - BL Direct - All 7 versions
- ►jlr.org JJFP Luiken, LP Turcotte, A Bonen - The Journal of Lipid Research, 1999 - ASBMB Giant sarcolemmal vesicles were isolated from rat heart and hindlimb muscles for a) characterization
of long-chain fatty acid transport in the absence of metabolism and b) comparison of fatty acid
transport protein expression with fatty acid transport. Giant vesicles contained cytosolic ... Cited by 127 - Related articles - BL Direct - All 3 versions