- ►diabetesjournals.org D Walcher, M Aleksic, V Jerg, V Hombach, A … - Diabetes, 2004 - Am Diabetes Assoc Increased levels of C-peptide, a cleavage product of proinsulin, circulate in
patients with insulin resistance and early type 2 diabetes, a high-risk
population for the development of a diffuse and extensive pattern of ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org N Marx, D Walcher, C Raichle, M Aleksic, H … - Arteriosclerosis, thrombosis, and vascular biology, 2004 - Am Heart Assoc Method and Results— We demonstrate significantly higher intimal C-peptide
deposition in thoracic artery specimens from young diabetic subjects compared
with matched nondiabetic controls as determined by immunohistochemical ... Cited by 35 - Related articles - BL Direct - All 9 versions
Y Kobayashi, K Naruse, Y Hamada, E … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 2396–2401 DOI 10.1007/s00125-005-1942-9 ARTICLE
Y. Kobayashi . K. Naruse . Y. Hamada . E. Nakashima . K. Kato . N. Akiyama . ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] T Kitamura, K Kimura, BD Jung, K Makondo, N … - Biochemical Journal, 2002 - pubmedcentral.nih.gov Proinsulin C-peptide has been reported to have some biological activities and to
be possibly involved in the development of diabetic microangiopathy. In the
present study, we examined the effects of C-peptide on the ... Cited by 31 - Related articles - BL Direct - All 10 versions
- ►nih.gov [PDF] T Kitamura, K Kimura, BD Jung, K Makondo, S … - Biochemical Journal, 2001 - pubmedcentral.nih.gov Page 1. Biochem. J. (2001) 355, 123–129 (Printed in Great Britain) 123 Proinsulin
C-peptide rapidly stimulates mitogen-activated protein kinases in ... Cited by 54 - Related articles - BL Direct - All 8 versions
Z Zhong, A Davidescu, I Ehrén, K Ekberg, H … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Accumulating evidence in- dicates that replacement of
C-peptide in type 1 diabetes ameliorates nerve and kidney dysfunction, but the
molec- ular mechanisms involved are incompletely understood. C-peptide ... Cited by 26 - Related articles - All 3 versions
- ►ksu.edu.sa [PDF] NM Al-Rasheed, F Meakin, EL Royal, AJ … - Diabetologia, 2004 - Springer Aims/hypothesis. Proinsulin C-peptide is generally be- lieved to be inert
without any appreciable biological functions. However, it has been shown to
modulate a variety of cellular processes important in the patho- physiology ... Cited by 21 - Related articles - BL Direct - All 8 versions
- ►ahajournals.org D Walcher, C Babiak, P Poletek, S Rosenkranz … - Circulation research, 2006 - Am Heart Assoc Increased levels of C-peptide, a cleavage product of proinsulin, circulate in
patients with insulin resistance and early type 2 diabetes mellitus. Recent data
suggest a potential causal role of C-peptide in atherogenesis by promoting ... Cited by 17 - Related articles - All 7 versions
- ►asnjournals.org NM Al-Rasheed, GB Willars, NJ Brunskill - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Cell loss by apoptosis occurs in renal injury such as diabetic nephropathy. TNF-
is a cytokine that induces apoptosis and has been implicated in the pathogenesis
of diabetic nephropathy. The aim was to investigate whether C-peptide or ... Cited by 19 - Related articles - BL Direct - All 11 versions
- Free from Publisher K Ekberg, T Brismar, BL Johansson, P … - Diabetes Care, 2007 - Am Diabetes Assoc RESULTS—The age of the 139 patients who completed the protocol was 44.2 ± 0.6
(mean ± SE) years and their duration of diabetes was 30.6 ± 0.8 years.
Clinical neurological impairment (NIA) (score >7 points) of the lower ... Cited by 35 - Related articles - BL Direct - All 5 versions