A Kubosaki, S Gross, J Miura, K Saeki, M Zhu … - Diabetes, 2004 - Am Diabetes Assoc Insulinoma-associated protein (IA)-2β, also known as phogrin, is an
enzymatically inactive member of the transmembrane protein tyrosine phosphatase
family and is located in dense-core secretory vesicles. In patients with ... Cited by 26 - Related articles - BL Direct - All 8 versions
A Kubosaki, S Nakamura, AL Notkins - Diabetes, 2005 - Am Diabetes Assoc IA-2 and IA-2β are members of the transmembrane protein tyrosine phosphatase
family located in dense core vesicles of neuroendocrine cells, including the
β-cells of pancreatic islets. In the present study, by mating C57BL/6Nci ... Cited by 12 - Related articles - BL Direct - All 5 versions
A Kubosaki, J Miura, AL Notkins - Diabetologia, 2004 - Springer 1. Lan MS, Wasserfall C, Maclaren NK, Notkins AL (1996) IA-2, a transmembrane
protein of the protein tyrosine phos- phatase family, is a major autoantigen in
insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 93:6367–6370 ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Kubosaki, S Nakamura, A Clark, JF Morris, … - Endocrinology, 2006 - Endocrine Soc Female infertility is a worldwide problem affecting 10–15% of the population.
The cause of the infertility in many cases is not known. In the present report,
we demonstrate that alterations in two transmembrane structural proteins, ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org K Saeki, M Zhu, A Kubosaki, J Xie, MS Lan, … - Diabetes, 2002 - Am Diabetes Assoc IA-2 is a major autoantigen in type 1 diabetes. Autoantibodies to IA-2 appear
years before the development of clinical disease and are being widely used as
predictive markers to identify individuals at risk for developing type 1 ... Cited by 61 - Related articles - BL Direct - All 4 versions
S Gross, C Blanchetot, J Schepens, S Albet, … - Journal of Biological Chemistry, 2002 - ASBMB Most receptor-type protein-tyrosine phosphatases (RPTPs) contain two tandem PTP
domains. For some RPTPs the enzymatically inactive membrane-distal phosphatase
domains (D2) were found to bind enzymatically active membrane proximal PTP ... Cited by 21 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] C Wasmeier, JC Hutton - Biochemical Journal, 1999 - pubmedcentral.nih.gov Phogrin, a 60\64 kDa integral membrane protein localized to dense-core secretory
granules of neuroendocrine cells, was found to be reversibly phosphorylated in
intact pancreatic β-cells. Phosphorylation occurred in response to a ... Cited by 34 - Related articles - BL Direct - All 8 versions
- ►nih.gov S Harashima, A Clark, MR Christie, AL … - Proceedings of the National Academy of Sciences, 2005 - National Acad Sciences IA-2 is an enzymatically inactive member of the transmembrane protein tyrosine
phosphate family located in dense core secretory vesicles and a major
autoantigen in type 1 diabetes. Recent studies showed that targeted ... Cited by 27 - Related articles - All 9 versions
YP Vo, JC Hutton, JK Angleson - Biochemical and Biophysical Research …, 2004 - Elsevier Phogrin (IA2-β) is an integral membrane protein of dense-core vesicles in
neuroendocrine cells. We have examined the recycling of endogenous phogrin
following exocytosis in insulin secreting Min6 β-cells by monitoring ... Cited by 16 - Related articles - All 4 versions
- ►jhc.org C Roberts, GA Roberts, K Lobner, M Bearzatto, … - Journal of Histochemistry and Cytochemistry, 2001 - Histochemical Soc PHOSPHORYLATION OF PROTEINS on serine, threonine, or tyrosine residues is a
major mechanism for the regulation of cellular processes, including exocytosis,
cell growth, and cell differentiation. Members of a novel family of protein ... Cited by 16 - Related articles - BL Direct - All 2 versions
