D Qi, T Pulinilkunnil, D An, S Ghosh, A … - Diabetes, 2004 - Am Diabetes Assoc Glucocorticoids impair insulin sensitivity. Because insulin resistance is
closely linked to increased incidence of cardiovascular diseases and given that
metabolic abnormalities have been linked to initiation of heart failure, we ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►physiology.org D Qi, D An, G Kewalramani, Y Qi, T … - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc Glucocorticoid therapy is often associated with impaired insulin sensitivity and
cardiovascular disease. The present study was designed to evaluate cardiac fatty
acid (FA) composition and metabolism following acute dexamethasone (Dex) ... Cited by 11 - Related articles - BL Direct - All 4 versions
- ►physiology.org G Kewalramani, P Puthanveetil, MS Kim, F … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Following dexamethasone (DEX), cardiac energy generation is mainly through
utilization of fatty acids (FA), with DEX animals demonstrating an increase in
coronary lipoprotein lipase (LPL), an enzyme that hydrolyzes lipoproteins ... Cited by 7 - Related articles - All 3 versions
T Pulinilkunnil, A Abrahani, J Varghese, N … - Journal of molecular and cellular cardiology, 2003 - Elsevier During diabetes, impaired glucose transport and utilization by the heart
switches energy production to exclusive β-oxidation of fatty acid (FA). In the
current study, we examined the contribution of cardiac lipoprotein lipase ... Cited by 19 - Related articles - All 4 versions
- ►physiology.org D An, T Pulinilkunnil, D Qi, S Ghosh, A … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc The "fuel gauge" AMP-activated protein kinase (AMPK) facilitates ATP production
to meet energy demands during metabolic stress. Given the importance of
lipoprotein lipase (LPL) in providing hearts with fatty acids (FA), the ... Cited by 37 - Related articles - All 4 versions
- ►nih.gov [PDF] HS Ewart, DL Severson - Biochemical Journal, 1999 - pubmedcentral.nih.gov Lipoprotein lipase (LPL) activity in cultured ventricular cardio- myocytes from
adult rat hearts was stimulated by the com- bination of insulin (100nM) and
dexamethasone (100nM) during an overnight (16 h) incubation. Wortmannin ... Cited by 18 - Related articles - BL Direct - All 8 versions
B Rodrigues, MC Cam, K Jian, F Lim, N … - Diabetes, 1997 - Am Diabetes Assoc Lipoprotein lipase (LPL) is an endothelial-bound enzyme that is rate determining
for the clearance of triacylglycerol-rich lipoproteins. Previous studies using
rats with streptozotocin (STZ)-induced diabetes have reported inconsistent ... Cited by 33 - Related articles - BL Direct - All 5 versions
- ►physiology.org T Pulinilkunnil, D An, S Ghosh, D Qi, G … - American Journal of Physiology- Heart and Circulatory …, 2005 - Am Physiological Soc The lipoprotein lipase (LPL)-augmenting property of lysophosphatidylcholine
requires the formation of lysophosphatidic acid (LPA) (J Mol Cell Cardiol 37:
931–938, 2004). Given that the actin cytoskeleton has been implicated in ... Cited by 12 - Related articles - All 4 versions
G Kewalramani, D An, MS Kim, S Ghosh, D Qi, … - Journal of molecular and cellular cardiology, 2007 - Elsevier Flexibility in substrate selection is essential for the heart to maintain
production of energy and contractile function, and is managed through multiple
mechanisms including PPAR-α and AMP-activated protein kinase (AMPK). Rats ... Cited by 14 - Related articles - All 11 versions
- ►cardiovascres.org T Pulinilkunnil, D Qi, S Ghosh, C Cheung, P … - Cardiovascular research, 2003 - cardiovascres.org Under physiological conditions, cardiac tissue acquires most of its energy from
metabolism of two major substrates, glucose and fatty acid (FA), the latter
being the preferred substrate consumed [1,2]. Because the heart has no ... Cited by 12 - Related articles - All 7 versions
