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Scholar Results 1 - 10 of about 101 related to Mizisin: Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration.... (0.09 sec) 

Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration deficits …


AP Mizisin, Y Vu, M Shuff, NA Calcutt - Diabetes, 2004 - Am Diabetes Assoc
Ciliary neurotrophic factor (CNTF) protein and bioactivity are reduced in the
peripheral nerve of hyperglycemic rats with a cause related to metabolism of
hexose sugars by aldose reductase. Here the efficacy of CNTF treatment ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase …


NA Calcutt, JD Freshwater, AP Mizisin - Diabetologia, 2004 - Springer
Aims/hypothesis. Sensory neuropathy in diabetic pa- tients frequently presents
itself as progressive loss of thermal perception, while some patients describe
con- current spontaneous pain, allodynia or hyperalgesia. Diabetic rats ...
Cited by 48 - Related articles - BL Direct - All 7 versions

Reduced ciliary neuronotrophic factor-like activity in nerves from diabetic or galactose-fed …


NA Calcutt, D Muir, HC Powell, AP Mizisin - Brain research, 1992 - ncbi.nlm.nih.gov
This study examined the levels of ciliary neuronotrophic factor (CNTF)-like
activity in the sciatic nerve of rats with short-term streptozotocin-induced
diabetes or dietary supplementation with 40% galactose. CNTF-like activity, ...
Cited by 34 - Related articles - All 3 versions

The neurocytokine, interleukin-6, corrects nerve dysfunction in experimental diabetes


NE Cameron, MA Cotter - Experimental neurology, 2007 - Elsevier
Interleukin-6 (IL-6) is a member of the neuropoietic cytokine family and has a
multifunctional biological role in regulating the immune response, acute phase
reactions, and hematopoiesis. IL-6 is also important in neural development ...
Cited by 7 - Related articles - All 3 versions

Aldose reductase inhibition increases CNTF-like bioactivity and protein in sciatic nerves …


AP Mizisin, NA Calcutt, PS DiStefano, A … - Diabetes, 1997 - Am Diabetes Assoc
The impact of exaggerated polyol pathway flux on ciliary neurotrophic factor
(CNTF)-like bioactivity and expression of CNTF in rat sciatic nerve was examined
after 2 months of galactose intoxication. Polyol content was elevated (P < ...
Cited by 30 - Related articles - BL Direct - All 5 versions

Growth factors as therapeutics for diabetic neuropathy


NA Calcutt, CG Jolivalt, P Fernyhough - Current Drug Targets, 2008 - ingentaconnect.com
Abstract: There has been a rapid growth in appreciation of the diverse array of
neurotrophic factors, growth factors and other biological molecules that have
the capacity to support adult neurons and direct reparative processes after ...
Cited by 9 - Related articles - BL Direct - All 2 versions

Modeling diabetic sensory neuropathy in rats


NA Calcutt - Methods in Molecular Medicine, 2004 - Springer
Summary The procedures to induce insulin-deficient diabetes in rats using
streptozotocin are described along with a number of insulin treatment regimes
that can be used to maintain these animals at different degrees of glycemia ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Stimulation of nerve growth factor and substance P expression in the iris–trigeminal axis of …


P Fernyhough, WJ Brewster, K Fernandes, LT … - Brain research, 1998 - Elsevier
In rats with streptozotocin-induced diabetes, we measured increased (by 61%;
P<0.05) mRNA for nerve growth factor (NGF) in the iris together with increased
(by 82%; P<0.05) mRNA for preprotachykinin (the substance P precursor) in ...
Cited by 11 - Related articles - All 6 versions

Interleukin-6 attenuates the development of experimental diabetes-related neuropathy


E Andriambeloson, C Baillet, PA Vitte, G … - Neuropathology, 2006 - interscience.wiley.com
Neuropathy is the most severe and the least understood complication of diabetes.
We investigated the potential neuroprotective effect of IL-6 therapy in an
experimental model of diabetic neuropathy. A single iv injection of ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Amelioration of diabetic peripheral neuropathy by implantation of hematopoietic mononuclear …


T Hasegawa, A Kosaki, K Shimizu, H … - Experimental neurology, 2006 - Elsevier
This study was performed in order to evaluate the angiogenic effect of
implantation of either peripheral blood mononuclear cells (PBMNCs) or bone
marrow mononuclear cells (BMMNCs) on diabetic peripheral neuropathy. ...
Cited by 13 - Related articles - All 4 versions


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