C Schoelch, J Kuhlmann, M Gossel, G Mueller, C … - Diabetes, 2004 - Am Diabetes Assoc Increased supply of fatty acids to muscle and liver is causally involved in the insulin resistance
syndrome. Using a tissue microdialysis technique in Wistar and Zucker fatty (ZF) rats, we determined
tissue glycerol levels as a marker of lipolysis in gastrocnemius muscle (gMT), ... Cited by 11 - Related articles - BL Direct - All 4 versions
B Shah, S Rohatagi, C Natarajan, S Kirkesseli … - American journal of …, 2004 - journals.lww.com RPR749 and its methylated metabolite are orally active and selective adenosine A 1 agonists
that can inhibit lipolysis and lower plasma triglyceride levels in a variety of animal models. RPR749
also appears to lower free fatty acid (FFA) and insulin levels and may have additional ... Cited by 5 - Related articles - BL Direct - All 3 versions
AK Dhalla, M Santikul, JW Chisholm, L … - Diabetes, Obesity and … - interscience.wiley.com Introduction and Aims: Elevated plasma free fatty acid (FFA) concentrations play a role in the
pathogenesis of type 2 diabetes (2DM). Antilipolytic agents that reduce FFA concentrations may
be potentially useful in the treatment of 2DM. Our previous observation that CVT-3619 ... Cited by 2 - Related articles - All 3 versions
HX Liang, L Belardinelli, MJ Ozeck, JC … - British journal of …, 2002 - pubmedcentral.nih.gov Adipocyte A 1 -adenosine receptors (A 1 AdoR) tonically inhibit adenylyl cyclase and
lipolysis. Three potential explanations for tonic activity of A 1 AdoR of rat epididymal adipocytes
were investigated: high affinity of adenosine for the receptor, efficient coupling of receptor ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►endojournals.org H Barakat, J Davis, D Lang, SJ Mustafa, MM … - Journal of Clinical …, 2006 - Endocrine Soc Context: African-American women (AAW) lose less weight and at a slower rate than Caucasian
women (CAW) under the same weight-loss regimens. A potential cause of this finding is inhibition
of lipolysis. ... Objective: Because -2 and adenosine receptors are directly involved in ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org AK Dhalla, M Santikul, M Smith, MY Wong, JC … - Journal of Pharmacology …, 2007 - ASPET Elevated lipolysis and circulating free fatty acid (FFA) levels have been linked to the pathogenesis
of insulin resistance. A 1 adenosine receptor agonists are potent inhibitors of lipolysis. Several
A 1 agonists have been tested as potential antilipolytic agents; however, their effect on ... Cited by 12 - Related articles - All 3 versions
- ►aspetjournals.org M Fatholahi, Y Xiang, Y Wu, Y Li, L Wu, AK Dhalla, L … - Journal of Pharmacology …, 2006 - ASPET This study characterizes the receptor binding and functional effects of CVT-3619 [2-{6-[((1R,2R
)-2-hydroxycyclopentyl)-amino]purin-9-yl}(4S,5S,2R,3R)-5-[(2-fluorophenylthio)methyl]-oxolane
-3,4-diol], a novel N 6 -5' -substituted adenosine analog and A 1 -adenosine receptor (A ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org H Fraser, Z Gao, MJ Ozeck, L Belardinelli - Journal of Pharmacology and …, 2003 - ASPET Elevated serum nonesterified free fatty acid (NEFA) concentrations are detrimental to both the
mechanical and electrical function of the heart. A 1 adenosine receptor agonists are potent and
efficacious inhibitors of lipolysis; however, their cardiovascular effects have limited their ... Cited by 9 - Related articles - BL Direct - All 3 versions
M Grden, M Podgorska, A Szutowicz, T Pawelczyk - … and Molecular Pathology, 2007 - Elsevier Diabetes mellitus is associated with metabolic, functional, and structural changes in the liver.
Adenosine has been demonstrated to play an important regulatory role in the liver, and its action
has been associated with all four adenosine receptors (ARs) subtypes. The goal of this ... Cited by 6 - Related articles - All 2 versions
JM Kaartinen, KF LaNoue, JJ Ohisalo - Biochimica et biophysica acta, 1994 - ncbi.nlm.nih.gov Antisera were raised in rabbits against synthetic peptides corresponding to sequences of the
guanine nucleotide binding proteins Gi1, Gi2, Gi3 and Go. These and previously described antisera
were used to identify different G-proteins in Western blots of human adipocyte plasma ... Cited by 8 - Related articles - All 2 versions
