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Scholar Results 1 - 10 of about 101 related to McCrimmon: Potential role for AMP-activated protein kinase in hypoglycemia sensing in the.... (0.14 sec) 

Potential role for AMP-activated protein kinase in hypoglycemia sensing in the …


RJ McCrimmon, X Fan, Y Ding, W Zhu, RJ … - Diabetes, 2004 - Am Diabetes Assoc
The mechanisms by which specialized glucose-sensing neurons within the
hypothalamus are able to detect a falling blood glucose remain largely unknown
but may be linked to some gauge of neuronal energy status. We sought to ...
Cited by 58 - Related articles - BL Direct - All 4 versions

Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies …

- diabetesjournals.org
RJ McCrimmon, X Fan, H Cheng, E McNay, O … - Diabetes, 2006 - Am Diabetes Assoc
Defective counterregulatory responses (CRRs) to hypoglycemia are associated with
a marked increase in the risk of severe hypoglycemia. The mechanisms leading to
the development of defective CRRs remain largely unknown, although they are ...
Cited by 28 - Related articles - BL Direct - All 5 versions

Hypothalamic AMP-activated protein kinase mediates counter-regulatory responses to …


SM Han, C Namkoong, PG Jang, IS Park, SW … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 2170–2178 DOI 10.1007/s00125-005-1913-1 ARTICLE
S.-M. Han . C. Namkoong . PG Jang . IS Park . SW Hong . H. Katakami . ...
Cited by 30 - Related articles - BL Direct - All 3 versions

Hypothalamic ATP-sensitive K+ channels play a key role in sensing hypoglycemia and …

- diabetesjournals.org
ML Evans, RJ McCrimmon, DE Flanagan, T … - Diabetes, 2004 - Am Diabetes Assoc
It has been postulated that specialized glucose-sensing neurons in the
ventromedial hypothalamus (VMH) are able to detect falling blood glucose and
trigger the release of counterregulatory hormones during hypoglycemia. The ...
Cited by 74 - Related articles - BL Direct - All 5 versions

[PDF] Glucosensing neurons in the ventromedial hypothalamic nucleus (VMN) and hypoglycemia- …


DMR Rev - Diabetes Metab Res Rev, 2003 - umdnj.edu
Diabetes Metab Res Rev 2003; 19: 348–356. Published online 12 August 2003 in
Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/dmrr.404 ...
Departments of Pharmacology & Physiology and Neurosciences, New Jersey ...
Cited by 34 - Related articles - View as HTML - BL Direct - All 5 versions

Enhanced hypothalamic AMP-activated protein kinase activity contributes to hyperphagia in …

- diabetesjournals.org
C Namkoong, MS Kim, PG Jang, SM Han, HS … - Diabetes, 2005 - Am Diabetes Assoc
AMP-activated protein kinase (AMPK) acts as a cellular energy sensor, being
activated during states of low energy charge. Hypothalamic AMPK activity is
altered by hormonal and metabolic signals and mediates the feeding ...
Cited by 36 - Related articles - All 7 versions

Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus …

- rutgers.edu [PDF] 
L Kang, VH Routh, EV Kuzhikandathil, LD … - Diabetes, 2004 - Am Diabetes Assoc
To evaluate potential mechanisms for neuronal glucosensing, fura-2 Ca 2+ imaging
and single-cell RT-PCR were carried out in dissociated ventromedial hypothalamic
nucleus (VMN) neurons. Glucose-excited (GE) neurons increased and glucose- ...
Cited by 94 - Related articles - BL Direct - All 7 versions

Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated …

- endojournals.org
K Lee, B Li, X Xi, Y Suh, RJ Martin - Endocrinology, 2005 - Endocrine Soc
Nutrient sensing in the hypothalamus is tightly related to food intake
regulation. However, the mechanisms by which the nutrient-sensing cells of the
brain translate this signal of energy need into feeding behavior via ...
Cited by 64 - Related articles - All 5 versions

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated …

- jbc.org
EK Kim, I Miller, S Aja, LE Landree, M Pinn, … - Journal of Biological Chemistry, 2004 - ASBMB
Energy homeostasis and feeding are regulated by the central nervous system. C75,
a fatty acid synthase (FAS) inhibitor, causes weight loss and anorexia, implying
a novel central nervous system pathway(s) for sensing energy balance. AMP- ...
Cited by 133 - Related articles - BL Direct - All 4 versions

Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires …


PD Mountjoy, SJ Bailey, GA Rutter - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Changes in the activity of glucose-excited and
glucose-inhibited neurons within the basomedial hypothalamus are key to the
central regulation of satiety. However, the molecular mechanisms through ...
Cited by 25 - Related articles - BL Direct - All 6 versions


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