T Pearson, P Weiser, TG Markees, DV Serreze … - Diabetes, 2004 - Am Diabetes Assoc NOD mice develop type 1 autoimmune diabetes and exhibit genetically dominant
resistance to transplantation tolerance induction. These two phenotypes are
genetically separable. Costimulation blockade fails to prolong skin ... Cited by 16 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org T Pearson, TG Markees, LS Wicker, DV … - Diabetes, 2003 - Am Diabetes Assoc The loss of self-tolerance leading to autoimmune type 1 diabetes in the NOD
mouse model involves at least 19 genetic loci. In addition to their genetic
defects in self-tolerance, NOD mice resist peripheral transplantation ... Cited by 21 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org EJ Gordon, LS Wicker, LB Peterson, DV … - Diabetes, 2005 - Am Diabetes Assoc Costimulation blockade induces prolonged rat islet and skin xenograft survival
in C57BL/6 mice. Nonobese diabetic (NOD) mice, which are used to model human
autoimmune diabetes, are resistant to costimulation blockade-induced ... Cited by 6 - Related articles - All 7 versions
HY Young, P Zucker, RA Flavell, AM Jevnikar, … - Transplantation, 2004 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 8 - Related articles - All 4 versions
DT Robles, GS Eisenbarth, NJM Dailey, LB … - Diabetes, 2003 - Am Diabetes Assoc Susceptibility to diabetes in humans and nonobese diabetic (NOD) mice is
believed to arise from the combined effect of multiple genetic loci, resulting
in immune-mediated destruction of the insulin-secreting β-cells. Insulin ... Cited by 28 - Related articles - BL Direct - All 4 versions
T Pearson, TG Markees, DV Serreze, MA … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2003 - interscience.wiley.com Abstract: Recent advances in islet transplantation have enabled physicians to
cure type 1 autoimmune diabetes, but at the cost of lifelong immunosuppression
with its attendant side effects and long-term health risks. To eliminate ... Cited by 11 - Related articles - BL Direct - All 7 versions
[CITATION] Congenic mapping of the type 1 diabetes locus, region of mouse chromosome 3: …
- ►jimmunol.org T Pearson, TG Markees, DV Serreze, MA … - The Journal of Immunology, 2003 - Am Assoc Immnol Curing type 1 diabetes by islet transplantation requires overcoming both
allorejection and recurrent autoimmunity. This has been achieved with systemic
immunosuppression, but tolerance induction would be preferable. Most islet ... Cited by 30 - Related articles - BL Direct - All 7 versions
R Kandaswamy, DER Sutherland - Transplantation proceedings, 2006 - Elsevier Transplant options for the diabetic recipient include pancreas and islet
transplantation. Pancreas transplantation has been increasingly performed in the
last 3 decades with increasing success rates. Nevertheless, islet ... Cited by 3 - Related articles - All 10 versions
PL Mottram, LJ Murray-Segal, W Han, Y Zhan … - Transplant Immunology, 2000 - Elsevier To compare the effectiveness of transgenic and systemic monoclonal antibody
therapy for pancreas transplantation, vascularised segmental pancreas allografts
from wild-type or transgenic pancreatic tissue that secreted monoclonal ... Cited by 3 - Related articles - All 2 versions
