- ►diabetesjournals.org S Hussain, KV Salojin, TL Delovitch - Diabetes, 2004 - Am Diabetes Assoc B-cells proliferate after B-cell receptor (BCR) stimulation and are deleted by
activation-induced cell death (AICD) during negative selection. We report that
B-cells from type 1 diabetes−susceptible NOD and type 1 ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org S Hussain, TL Delovitch - The Journal of Immunology, 2005 - Am Assoc Immnol Little is known about the pathogenic role of B cell dysfunction in T
cell-mediated autoimmune disease. We previously reported that B cell
hyper-responsiveness, resistance to apoptosis, and accumulation in islets ... Cited by 21 - Related articles - All 5 versions
- ►jimmunol.org PPL Chiu, AM Jevnikar, JS Danska - The Journal of Immunology, 2001 - Am Assoc Immnol Type 1 diabetes in nonobese diabetic (NOD) mice is characterized by the
infiltration of T and B cells into pancreatic islets. T cells bearing the TCR V
3 chain are disproportionately represented in the earliest stages of islet ... Cited by 10 - Related articles - BL Direct - All 4 versions
PL Kendall, EJ Woodward, C Hulbert, JW … - European journal of immunology, 2004 - interscience.wiley.com Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of
insulin-producing beta cells in the pancreatic islets. Although T1DM is mediated
by T lymphocytes, B lymphocytes are essential for insulitis and disease ... Cited by 12 - Related articles - BL Direct - All 3 versions
FS Wong, L Wen - The Review of Diabetic Studies, 2005 - pubmedcentral.nih.gov Autoantibodies have been used as good markers for the prediction of future
development of type 1 diabetes mellitus (T1DM), but are not thought to be
pathogenic in this disease. The role of B cells that produce autoantibodies ... Cited by 8 - Related articles - All 6 versions
A Rojas, FP Xu, M Rojas, JW Thomas - Autoimmunity, 2003 - informahealthcare.com Type I or insulin dependent diabetes mellitus develops in the non-obese diabetic
(NOD) mouse as a consequence of T cell mediated autoimmune attack on pancreatic
beta cells. B lymphocytes are required for disease progression in NOD and ... Cited by 8 - Related articles - BL Direct - All 6 versions
- ►shouxi.net MC Puertas, J Carrillo, X Pastor, RM Ampudia, … - Diabetes, 2007 - Am Diabetes Assoc B-cells participate in the autoimmune response that precedes the onset of type 1
diabetes, but how these cells contribute to disease progression is unclear. In
this study, we analyzed the phenotype and functional characteristics of ... Cited by 1 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org J Rolf, V Motta, N Duarte, M Lundholm, E … - The Journal of Immunology, 2005 - Am Assoc Immnol The NOD mouse is an important experimental model for human type 1 diabetes. T
cells are central to NOD pathogenesis, and their function in the autoimmune
process of diabetes has been well studied. In contrast, although recognized ... Cited by 20 - Related articles - All 5 versions
- ►diabetesjournals.org [PDF] CJ Fox, JS Danska - Diabetes, 1998 - Am Diabetes Assoc Genetic susceptibility to type 1 diabetes in the nonobese diabetic (NOD) mouse
involves at least 17 Idd loci. I dd 1 has been mapped to a class II gene in the
major histo- compatibility complex (MHC), whereas the products and ... Cited by 41 - Related articles - BL Direct - All 4 versions
[CITATION] JR Serie, OD Hegre. 1991. Comparative analysis of potency of splenic dendritic and …
