JI Elliott, CF Higgins - Diabetes, 2004 - Am Diabetes Assoc It has been hypothesized that type 1 diabetes is initiated by neonatal physiological pancreatic
β-cell death, indicating that the early stages of this autoimmune response may reflect a dysregulated
response to immune “danger” signals. One potential danger signal is ATP, high ... Cited by 16 - Related articles - BL Direct - All 4 versions
J Elliott, J McVey, C Higgins - Arthritis Research & Therapy, 2005 - arthritis-research.com Systemic lupus erythematosus and its murine equivalent, modelled in the New Zealand Black
and New Zealand White (NZB × NZW)F 1 hybrid strain, are polygenic inflammatory
diseases, probably reflecting an autoimmune response to debris from cells undergoing ... Cited by 16 - Related articles - Cached - All 7 versions
R Coutinho-Silva, LA Alves, AC Campos de Carvalho, … - BBA-Biomembranes, 1996 - Elsevier The thymic microenvironment is under intrinsic and extrinsic control circuits by several elements
including hormones, neuropeptides, lymphokines, innervation and cell contact. P 2 purinergic
receptors have been described in a number of cells including macrophages, thymocytes, ... Cited by 11 - Related articles - All 3 versions
U Thunberg, G Tobin, A Johnson, O Söderberg, L … - The Lancet, 2002 - Elsevier Of the 170 patients, 35 (21%) were heterozygous and one (1%) homozygous for the 1513C
allele; whereas 134 (79%) had the 1513A/A genotype of the P2X7 receptor gene. Overall survival
was significantly longer for patients with CLL heterozygous for the 1513C allele than ... Cited by 53 - Related articles - All 5 versions
- ►jbc.org BJ Gu, R Sluyter, KK Skarratt, AN Shemon, LP Dao- … - Journal of Biological …, 2004 - ASBMB The P2X 7 receptor is a ligand-gated channel that is highly expressed on mononuclear cells
of the immune system and that mediates ATP-induced apoptosis. Wide variations in the function
of the P2X receptor have been observed, explained in part by 7 loss-of-function ... Cited by 57 - Related articles - BL Direct - All 7 versions
SL Haas, A Ruether, MV Singer, S Schreiber, … - … Journal of Immunology, 2007 - pt.wkhealth.com Genetic factors contribute to inflammatory bowel diseases. Recently, the P2X 7 receptor was
found to be a key player in caspase-1-mediated processing of the proinflammatory
cytokines, interleukin-1β and interleukin-18. We therefore aimed to determine whether the ... Cited by 2 - Related articles - BL Direct - All 6 versions
- ►shouxi.net SL Fernando, BM Saunders, R Sluyter, KK … - The Journal of …, 2005 - UChicago Press Featured in US News & World Report "Common Cold Virus Alters Body's Genes" October
24, 2008 Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus
(RSV) Vaccines— Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum—Given ... Cited by 26 - Related articles - All 7 versions
LP Dao-Ung, SJ Fuller, R Sluyter, KK SkarRatt … - British journal of …, 2004 - chs.usyd.edu.au Introduction B-cell chronic lymphocytic leukaemia (CLL) is unique in showing a three-fold increased
incidence in closely related family members compared to other lymphoproliferative
diseases1. P2X7 is a cytolytic receptor expressed in many cell types, which can be ... Cited by 23 - Related articles - View as HTML - BL Direct - All 8 versions
K Wirkner, A Kofalvi, W Fischer, A Gunther … - Journal of …, 2005 - interscience.wiley.com Neuronally enriched primary cerebrocortical cultures were exposed to glucose-free medium
saturated with argon (in vitro ischemia) instead of oxygen (normoxia). Ischemia did not alter P2X
7 receptor mRNA, although serum deprivation clearly increased it. Accordingly, P2X 7 ... Cited by 24 - Related articles - BL Direct - All 5 versions