YQ Zhang, MM Cleary, Y Si, G Liu, Y Eto, M … - Diabetes, 2004 - Am Diabetes Assoc Activins regulate the growth and differentiation of a variety of cells. During
pancreatic islet development, activins are required for the specialization of
pancreatic precursors from the gut endoderm during midgestation. In this ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►nih.gov SS Tulachan, E Tei, M Hembree, C Crisera, K … - Developmental biology, 2007 - Elsevier Transforming growth factor-beta (TGF-β) superfamily signaling has been
implicated in many developmental processes, including pancreatic development.
Previous studies are conflicting with regard to an exact role for TGF-β ... Cited by 8 - Related articles - All 4 versions
- ►pnas.org P Bertolino, R Holmberg, E Reissmann, O … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences All major cell types in pancreatic islets express the transforming growth factor
(TGF)-β superfamily receptor ALK7, but the physiological function of this
receptor has been unknown. Mutant mice lacking ALK7 showed normal pancreas ... Cited by 8 - Related articles - BL Direct - All 7 versions
- ►cell.com M Gannon - Cell metabolism, 2007 - Elsevier Type 2 diabetes results from combined insulin resistance in peripheral
insulin-responsive tissues (liver, muscle, and fat) and decreased functional β
cell mass. In normal β cells, glucose metabolism leads to increased ... Cited by 4 - Related articles - All 10 versions
N Sekine, N Yamashita, I Kojima, J Miyazaki, … - Diabetes research and clinical practice, 1994 - ncbi.nlm.nih.gov The effects of transforming growth factor-beta (TGF-beta) on insulin secretion
were investigated using a glucose-responsive clonal cell line, MIN6. One hundred
pM TGF-beta stimulated insulin release during 0.5-24 h of incubation in the ... Cited by 8 - Related articles - All 3 versions
RS Bindra, PM Glazer - Cancer biology & therapy, 2006 - ncbi.nlm.nih.gov The BRCA1 gene is rarely mutated in sporadic tumors, although numerous studies
suggest that the expression of this critical tumor suppressor gene is frequently
downregulated in tumors derived from a wide range of tissues. However, ... Cited by 9 - Related articles - BL Direct - All 4 versions
T Ogihara, H Watada, R Kanno, F Ikeda, T … - Journal of Biological Chemistry, 2003 - ASBMB Neurogenin3 (ngn3) is a transcription factor that is essential for the
differentiation of pancreatic endocrine cells. To investigate the signaling
pathway that regulates ngn3 expression, we used AR42J-B13 cells as a model ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►endojournals.org YQ Zhang, H Zhang, A Maeshima, H Kurihara, … - Endocrinology, 2002 - Endocrine Soc Activins expressed in progenitor cells of the pancreas regulate differentiation
of endocrine cells during development. Neogenesis of ß-cells takes place in
adult animals under some conditions, and ß-cells are thought to arise from ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►jbc.org H Hua, YQ Zhang, S Dabernat, M Kritzik, D … - Journal of Biological Chemistry, 2006 - ASBMB Inhibitor of DNA binding (Id) proteins bind to and inhibit the function of basic
helix-loop-helix (bHLH) transcription factors including those that regulate
pancreatic development. Moreover, bone morphogenetic proteins (BMPs) ... Cited by 27 - Related articles - BL Direct - All 7 versions
- ►jbc.org [PDF] H Collins, H Najafi, C Buettger, J Rombeau, … - Journal of Biological Chemistry, 1992 - ASBMB Page 1. THE JOURNAL OF BIOLOGICAL CHEMISTRY 0 1992 by The American Society for
Biochemistry and Molecular Biology, Inc Vol. 267, No. 2, Issue of January 15, pp. ... Cited by 13 - Related articles - All 5 versions
