E Hammar, G Parnaud, D Bosco, N Perriraz, K Maedler … - Diabetes, 2004 - Am Diabetes Assoc We have shown previously that culture of β-cells on matrix derived from 804G cells and rich in
laminin-5 improves their function. The purpose of this study was to investigate whether this matrix
protects β-cells against apoptosis and to elucidate signaling pathways involved. Matrix ... Cited by 40 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org G Parnaud, E Hammar, DG Rouiller, M Armanet, PA … - Diabetes, 2006 - Am Diabetes Assoc When attached on a matrix produced by a rat bladder carcinoma cell line (804G matrix), rat pancreatic
β-cells spread in response to glucose and secrete more insulin compared with cells attached
on poly-l-lysine. The aim of this study was to determine whether laminin-5 and its ... Cited by 22 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] D Bosco, P Meda, PA Halban, DG Rouiller - Diabetes, 2000 - Am Diabetes Assoc It has long been recognized that islet cell function is rapidly altered in vitro, but can be
maintained, at least in part, when cells are layered on defined extracellular matrices. The present
work addresses the influence of short-term cell-matrix interactions on islet -cell func- tion ... Cited by 90 - Related articles - BL Direct - All 5 versions
NK Yashpal, J Li, MB Wheeler, R Wang - Endocrinology, 2005 - Endocrine Soc The integrin receptors link to extracellular matrix proteins and exert a dynamic role in development
by providing the physical basis for cell adhesion and controlling cell growth. In the present
study, we examined changes in the expression of ß1 integrins and its associated ... Cited by 26 - Related articles - All 5 versions
T Kaido, M Yebra, V Cirulli, AM Montgomery - Journal of Biological Chemistry, 2004 - ASBMB Collagens have been shown to influence the survival and function of cultured -cells;
however, the utilization and function of individual collagen receptors in -cells is largely
unknown. The integrin superfamily contains up to five collagen receptors, but we have ... Cited by 32 - Related articles - All 4 versions
[CITATION] Importance of cell-matrix interactions in rat islet-cell secretion in vitro: role of 6 1 …
- ►endocrinology-journals.org [PDF] RN Wang, L Rosenberg - Journal of Endocrinology, 1999 - Soc Endocrinology Islet transplantation is associated with a high rate of early graft failure, a problem that remains
poorly understood. It is probable that the destruction of the islet microenviron- ment and loss
of tropic support that occur during isolation lead to compromised survival. The purpose of ... Cited by 83 - Related articles - BL Direct - All 6 versions
K Edamura, K Nasu, Y Iwami, H Ogawa, N Sasaki, … - Cell …, 2003 - ncbi.nlm.nih.gov The effect of either adhesion or collagen molecules on cell attachment, insulin secretion, and
glucose responsiveness was investigated in adult porcine pancreatic endocrine (PE) cells that
were cultured for a longer term in vitro. Six different types of molecules--laminin, ... Cited by 17 - Related articles - BL Direct
S Kantengwa, D Baetens, K Sadoul, CA Buck, PA … - Experimental cell …, 1997 - Elsevier Dispersed rat islet cells embedded in a matrix of collagen I are known to form aggregatesin vitroreminiscent
of native islets. Furthermore, it appears that islet function and survival are better maintainedin
vitrowhen cells are grown in the presence of extracellular matrix. These studies suggest ... Cited by 29 - Related articles - All 6 versions
- ►diabetesjournals.org R Wang, J Li, K Lyte, NK Yashpal, F Fellows, CG … - Diabetes, 2005 - Am Diabetes Assoc The integrin receptors play a major role in tissue morphogenesis and homeostasis by regulating
cell interactions with extracellular matrix proteins. We have examined the expression pattern
of integrin subunits in the human fetal pancreas (8–20 weeks fetal age) and the relevance ... Cited by 23 - Related articles - All 4 versions
