R Basu, RJ Singh, A Basu, EG Chittilapilly, … - Diabetes, 2004 - Am Diabetes Assoc Glucocorticoids are potent regulators of protein, fat, and carbohydrate
metabolism. To determine if cortisol production occurs within the splanchnic bed
in humans, 11 nondiabetic subjects were studied using the hepatic/leg ... Related articles - All 2 versions
R Basu, R Singh, A Basu, CM Johnson, RA … - Diabetes, 2006 - Am Diabetes Assoc The splanchnic bed produces cortisol at rates approximating extraadrenal tissues
by converting cortisone to cortisol via the 11β-hydroxysteroid dehydrogenase
(11β-HSD) type 1 pathway. It is not known whether splanchnic cortisol ... Cited by 16 - Related articles - BL Direct - All 4 versions
R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ... Cited by 3 - Related articles - All 3 versions
JW Tomlinson, PM Stewart - Drug Discovery Today: Therapeutic Strategies, 2005 - Elsevier The pathophysiological importance of glucocorticoids is exemplified in patients
with Cushing's syndrome who develop central obesity, hypertension and increased
cardiovascular mortality as a consequence of circulating cortisol excess. ... Cited by 2 - Related articles
- ►endojournals.org [PDF] MN Kerstens, RPF Dullaart - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Cortisol Metabolism and Glucose Intolerance To the editor: Andrews et al. (1)
recently reported abnormalities in cortisol metab- olism and cortisol tissue
sensitivity in a group of male patients with either type 2 diabetes ... Related articles - BL Direct - All 4 versions
- ►aspetjournals.org DEW Livingstone, BR Walker - Journal of Pharmacology and Experimental …, 2003 - ASPET In liver and adipose tissue, 11 -hydroxysteroid dehydrogenase type 1 (11 -HSD1)
regenerates glucocorticoids from inactive 11-keto metabolites. Pharmacological
inhibition or transgenic disruption of 11 -HSD1 attenuates glucocorticoid ... Cited by 49 - Related articles - BL Direct - All 3 versions
- ►endojournals.org [PDF] BR Walker, R Andrew - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Cortisol Metabolism and Glucose Intolerance To the editor: Andrews et al. (1)
recently reported abnormalities in cortisol metab- olism and cortisol tissue
sensitivity in a group of male patients with either type 2 diabetes ... Related articles - BL Direct - All 2 versions
- ►endojournals.org G Valsamakis, A Anwar, JW Tomlinson, CHL … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Circulating F:E ratios were elevated in the diabetic group and correlated with
serum cholesterol and homeostasis model assessment-S. There was no difference in
11ß-HSD1 activity between diabetic subjects and controls. In addition, ... Cited by 73 - Related articles - BL Direct - All 6 versions
BR Walker - Diabetologia, 2004 - Springer Adipose tissue is increasingly recognised as an “endo- crine factory”,
releasing many newly identified hor- mones such as leptin, resistin, adiponectin
etc. These discoveries have stirred enthusiasm for investigating ... Cited by 10 - Related articles - BL Direct - All 3 versions