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Scholar Results 1 - 10 of about 101 related to Basu: Splanchnic Cortisol Production Occurs in Humans. (0.10 sec) 

Splanchnic Cortisol Production Occurs in Humans


R Basu, RJ Singh, A Basu, EG Chittilapilly, … - Diabetes, 2004 - Am Diabetes Assoc
Glucocorticoids are potent regulators of protein, fat, and carbohydrate
metabolism. To determine if cortisol production occurs within the splanchnic bed
in humans, 11 nondiabetic subjects were studied using the hepatic/leg ...
Related articles - All 2 versions

Obesity and type 2 diabetes do not alter splanchnic cortisol production in humans

- endojournals.org
R Basu, RJ Singh, A Basu, EG Chittilapilly, … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Endocrine Society JCEM ...
Cited by 27 - Related articles - BL Direct - All 5 versions

Effect of nutrient ingestion on total-body and splanchnic cortisol production in humans


R Basu, R Singh, A Basu, CM Johnson, RA … - Diabetes, 2006 - Am Diabetes Assoc
The splanchnic bed produces cortisol at rates approximating extraadrenal tissues
by converting cortisone to cortisol via the 11β-hydroxysteroid dehydrogenase
(11β-HSD) type 1 pathway. It is not known whether splanchnic cortisol ...
Cited by 16 - Related articles - BL Direct - All 4 versions

Liver is the site of splanchnic cortisol production in obese nondiabetic humans


R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ...
Cited by 3 - Related articles - All 3 versions

11β-Hydroxysteroid dehydrogenase type 1 as a therapeutic target in the metabolic …


JW Tomlinson, PM Stewart - Drug Discovery Today: Therapeutic Strategies, 2005 - Elsevier
The pathophysiological importance of glucocorticoids is exemplified in patients
with Cushing's syndrome who develop central obesity, hypertension and increased
cardiovascular mortality as a consequence of circulating cortisol excess. ...
Cited by 2 - Related articles

Cortisol Metabolism and Glucose Intolerance

- endojournals.org [PDF] 
MN Kerstens, RPF Dullaart - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Cortisol Metabolism and Glucose Intolerance To the editor: Andrews et al. (1)
recently reported abnormalities in cortisol metab- olism and cortisol tissue
sensitivity in a group of male patients with either type 2 diabetes ...
Related articles - BL Direct - All 4 versions

Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of …

- aspetjournals.org
DEW Livingstone, BR Walker - Journal of Pharmacology and Experimental …, 2003 - ASPET
In liver and adipose tissue, 11 -hydroxysteroid dehydrogenase type 1 (11 -HSD1)
regenerates glucocorticoids from inactive 11-keto metabolites. Pharmacological
inhibition or transgenic disruption of 11 -HSD1 attenuates glucocorticoid ...
Cited by 49 - Related articles - BL Direct - All 3 versions

Cortisol Metabolism in Type 2 Diabetes

- endojournals.org [PDF] 
BR Walker, R Andrew - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Cortisol Metabolism and Glucose Intolerance To the editor: Andrews et al. (1)
recently reported abnormalities in cortisol metab- olism and cortisol tissue
sensitivity in a group of male patients with either type 2 diabetes ...
Related articles - BL Direct - All 2 versions

11 {beta}-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 …

- endojournals.org
G Valsamakis, A Anwar, JW Tomlinson, CHL … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
Circulating F:E ratios were elevated in the diabetic group and correlated with
serum cholesterol and homeostasis model assessment-S. There was no difference in
11ß-HSD1 activity between diabetic subjects and controls. In addition, ...
Cited by 73 - Related articles - BL Direct - All 6 versions

Is “Cushing's disease of the omentum” an affliction of mouse and men?


BR Walker - Diabetologia, 2004 - Springer
Adipose tissue is increasingly recognised as an “endo- crine factory”,
releasing many newly identified hor- mones such as leptin, resistin, adiponectin
etc. These discoveries have stirred enthusiasm for investigating ...
Cited by 10 - Related articles - BL Direct - All 3 versions


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