- ►diabetesjournals.org AE Jackson, PG Cassell, BV North, S Vijayaraghavan, … - Diabetes, 2004 - Am Diabetes Assoc The neurogenic differentiation-1 (NEUROD1), neurogenin-3 (NEUROG3), and hepatic nuclear
factor-1α (TCF1) genes are interacting transcription factors implicated in controlling islet cell
development and insulin secretion. Polymorphisms of these genes (Ala45Thr ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SA Urhammer, T Hansen, CT Ekstrom, H Eiberg … - Journal of Clinical …, 1998 - Endocrine Soc The third form of maturity-onset diabetes of the young is caused by mutations in the hepatocyte
nuclear factor-1 gene. Recently, we demonstrated an association between a prevalent polymorphism
at codon 98, Ala/Val98, of this gene and a 20% decreased insulin release during an oral ... Cited by 24 - Related articles - BL Direct - All 4 versions
SA Urhammer, M Fridberg, T Hansen, SK Rasmussen, … - Diabetes, 1997 - Am Diabetes Assoc Mutations in the hepatocyte nuclear factor-1alpha (HNF-1alpha) gene cause the type 3 form
of maturity-onset diabetes of the young (MODY3), which is characterized by a severe impairment
of insulin secretion. In addition to disease-associated mutations, three common amino ... Cited by 44 - Related articles - BL Direct - All 5 versions
[CITATION] Lack of association of the Ala45Thr variant in the NeuroD/BETA2 with type 1 …
T Awata, K Inoue, I Inoue, T Abe, H Takino, KS … - Diab Res Clin Pract, 2000 Cited by 2 - Related articles
[CITATION] Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1 gene and …
- ►endojournals.org KC Chiu, LM Chuang, JM Ryu, GP Tsai, MF … - Journal of Clinical …, 2000 - Endocrine Soc Mutations of the hepatic nuclear factor-1 (HNF-1 ) gene have been found in patients with
maturity-onset diabetes of the young. We examined the relation between the I27L polymorphism
of HNF-1 and insulin sensitivity and ß-cell function assessed by a hyperglycemic clamp. ... Cited by 15 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] J Rissanen, H Wang, R Miettinen, P Karkkainen, P … - Diabetes Care, 2000 - Am Diabetes Assoc Late-onset type 2 diabetes is a complex familial disease characterized by vary- ing degrees of
ß-cell dysfunction and insulin resistance. Recently, gene defects in the hepatocyte nuclear factor
(HNF)-1a and HNF-4a genes have been identified in patients with dominantly inherited ... Cited by 26 - Related articles - All 5 versions
J Rissanen, H Wang, R Miettinen, P Karkkainen, P … - Diabetes Care, 2000 - Am Diabetes Assoc L ate-onset type 2 diabetes is a complex familial disease characterized by vary- ing degrees
of -cell dysfunction and insulin resistance. Recently, gene defects in the hepatocyte nuclear factor
(HNF)-1 and HNF-4 genes have been identified in patients with dominantly inherited and ... Cited by 6 - Related articles
JN Jensen, L Hansen, CT Ekstrøm, F Pociot, J Nerup, T … - Diabetologia, 2001 - Springer HNF-1b, the insulin promotor factor (IPF)-1 and neuronal determation factor (NeuroD). The
NEU- ROG3 is a new member of the subfamily of basic-he- lix-loop-helix (bHLH) class B transcription
factors involved in triggering NeuroD expression in the en- docrine pancreatic precursor ... Cited by 7 - Related articles - BL Direct - All 3 versions
J Lauenborg, P Damm, J Ek, C Glumer, T … - Diabetic …, 2004 - interscience.wiley.com Aims In pregnancies complicated by gestational diabetes mellitus (GDM) an increased demand
for insulin is not met due to β-cell dysfunction. An Ala/Val polymorphism at codon 98 of the hepatocyte
nuclear factor-1α (HNF-1α) gene has been associated with decreased serum insulin and ... Cited by 7 - Related articles - BL Direct - All 4 versions
