A Suzuki, H Nakauchi, H Taniguchi - Diabetes, 2004 - Am Diabetes Assoc During pancreatic development, neogenesis, and regeneration, stem cells might
act as a central player to generate endocrine, acinar, and duct cells. Although
these cells are well known as pancreatic stem cells (PSCs), indisputable ... Cited by 138 - Related articles - BL Direct - All 4 versions
RM Seaberg, SR Smukler, TJ Kieffer, G … - Nature Biotechnology, 2004 - utoronto.ca The clonal isolation of putative adult pancreatic precursors has been an elusive
goal of researchers seeking to develop cell replacement strategies for diabetes.
We report the clonal identification of multipotent precursor cells from the ... Cited by 262 - Related articles - BL Direct - All 13 versions
- ►diabetesjournals.org R Gao, J Ustinov, MA Pulkkinen, K Lundin, O … - Diabetes, 2003 - Am Diabetes Assoc We have reproduced a previously described method for the in vitro generation of
endocrine cells in adult human pancreatic tissue culture. The aim of this study
was to characterize the nature of pancreatic progenitor cells and to ... Cited by 154 - Related articles - BL Direct - All 7 versions
MC Gershengorn, AA Hardikar, C Wei, E … - Science, 2004 - sciencemag.org Insulin-expressing beta cells, found in pancreatic islets, are capable of
generating more beta cells even in the adult. We show that fibroblast-like cells
derived from adult human islets donated postmortem proliferate readily in ... Cited by 184 - Related articles - All 11 versions
- ►tamu-commerce.edu [PDF] DQ Tang, LZ Cao, BR Burkhardt, CQ Xia, SA … - Diabetes, 2004 - Am Diabetes Assoc Efforts toward routine islet cell transplantation as a means for reversing type
1 diabetes have been hampered by islet availability as well as allograft
rejection. In vitro transdifferentiation of mouse bone marrow (BM)-derived ... Cited by 212 - Related articles - BL Direct - All 7 versions
L Baeyens, S De Breuck, J Lardon, JK … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Transplantation of insulin- producing beta cells from
donors can cure diabetes, but they are available in insufficient quantities. In
this study, we investigated the possibility of generating insulin- ... Cited by 93 - Related articles - All 6 versions
A Lechner, AL Nolan, RA Blacken, JF … - Biochemical and Biophysical Research …, 2005 - Elsevier Cellular replacement therapy holds promise for the treatment of diabetes
mellitus but donor tissue is severely limited. Therefore, we investigated
whether insulin-secreting cells could be differentiated in vitro from a ... Cited by 60 - Related articles - All 4 versions
- ►umich.edu [PDF] MK Treutelaar, JM Skidmore, CL Dias-Leme, … - Diabetes, 2003 - Am Diabetes Assoc To clarify the lineage relationship between cells that express the neural stem
cell marker nestin and endocrine cells of the pancreas, we analyzed offspring of
a cross between mice carrying a nestin promoter/enhancer-driven ... Cited by 114 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org A Lechner, YG Yang, RA Blacken, L Wang, AL … - Diabetes, 2004 - Am Diabetes Assoc Several recent studies have suggested that the adult bone marrow harbors cells
that can differentiate into tissues from all three germ layers. Other reports
have contradicted these findings or attributed them to cell fusion. In this ... Cited by 112 - Related articles - BL Direct - All 4 versions
- ►massgeneral.org [PDF] S Kodama, W Kuhtreiber, S Fujimura, EA … - Science, 2003 - sciencemag.org Nonobese diabetic (NOD) mice are a model for type 1 diabetes in humans.
Treatment of NOD mice with end-stage disease by injection of donor splenocytes
and complete Freund's adjuvant eliminates autoimmunity and permanently ... Cited by 245 - Related articles - All 12 versions