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Scholar Results 1 - 10 of about 101 related to Suzuki: Prospective isolation of multipotent pancreatic progenitors using flow-cytometric.... (0.10 sec) 

Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting


A Suzuki, H Nakauchi, H Taniguchi - Diabetes, 2004 - Am Diabetes Assoc
During pancreatic development, neogenesis, and regeneration, stem cells might
act as a central player to generate endocrine, acinar, and duct cells. Although
these cells are well known as pancreatic stem cells (PSCs), indisputable ...
Cited by 138 - Related articles - BL Direct - All 4 versions

[PDF] Clonal identification of multipotent precursors from adult mouse pancreas that generate …


RM Seaberg, SR Smukler, TJ Kieffer, G … - Nature Biotechnology, 2004 - utoronto.ca
The clonal isolation of putative adult pancreatic precursors has been an elusive
goal of researchers seeking to develop cell replacement strategies for diabetes.
We report the clonal identification of multipotent precursor cells from the ...
Cited by 262 - Related articles - BL Direct - All 13 versions

Characterization of endocrine progenitor cells and critical factors for their differentiation in …

- diabetesjournals.org
R Gao, J Ustinov, MA Pulkkinen, K Lundin, O … - Diabetes, 2003 - Am Diabetes Assoc
We have reproduced a previously described method for the in vitro generation of
endocrine cells in adult human pancreatic tissue culture. The aim of this study
was to characterize the nature of pancreatic progenitor cells and to ...
Cited by 154 - Related articles - BL Direct - All 7 versions

Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells


MC Gershengorn, AA Hardikar, C Wei, E … - Science, 2004 - sciencemag.org
Insulin-expressing beta cells, found in pancreatic islets, are capable of
generating more beta cells even in the adult. We show that fibroblast-like cells
derived from adult human islets donated postmortem proliferate readily in ...
Cited by 184 - Related articles - All 11 versions

In vivo and in vitro characterization of insulin-producing cells obtained from murine bone …

- tamu-commerce.edu [PDF] 
DQ Tang, LZ Cao, BR Burkhardt, CQ Xia, SA … - Diabetes, 2004 - Am Diabetes Assoc
Efforts toward routine islet cell transplantation as a means for reversing type
1 diabetes have been hampered by islet availability as well as allograft
rejection. In vitro transdifferentiation of mouse bone marrow (BM)-derived ...
Cited by 212 - Related articles - BL Direct - All 7 versions

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells


L Baeyens, S De Breuck, J Lardon, JK … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: Transplantation of insulin- producing beta cells from
donors can cure diabetes, but they are available in insufficient quantities. In
this study, we investigated the possibility of generating insulin- ...
Cited by 93 - Related articles - All 6 versions

Redifferentiation of insulin-secreting cells after in vitro expansion of adult human pancreatic …


A Lechner, AL Nolan, RA Blacken, JF … - Biochemical and Biophysical Research …, 2005 - Elsevier
Cellular replacement therapy holds promise for the treatment of diabetes
mellitus but donor tissue is severely limited. Therefore, we investigated
whether insulin-secreting cells could be differentiated in vitro from a ...
Cited by 60 - Related articles - All 4 versions

Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet

- umich.edu [PDF] 
MK Treutelaar, JM Skidmore, CL Dias-Leme, … - Diabetes, 2003 - Am Diabetes Assoc
To clarify the lineage relationship between cells that express the neural stem
cell marker nestin and endocrine cells of the pancreas, we analyzed offspring of
a cross between mice carrying a nestin promoter/enhancer-driven ...
Cited by 114 - Related articles - BL Direct - All 5 versions

No evidence for significant transdifferentiation of bone marrow into pancreatic β-cells in vivo

- diabetesjournals.org
A Lechner, YG Yang, RA Blacken, L Wang, AL … - Diabetes, 2004 - Am Diabetes Assoc
Several recent studies have suggested that the adult bone marrow harbors cells
that can differentiate into tissues from all three germ layers. Other reports
have contradicted these findings or attributed them to cell fusion. In this ...
Cited by 112 - Related articles - BL Direct - All 4 versions

Islet regeneration during the reversal of autoimmune diabetes in NOD mice

- massgeneral.org [PDF] 
S Kodama, W Kuhtreiber, S Fujimura, EA … - Science, 2003 - sciencemag.org
Nonobese diabetic (NOD) mice are a model for type 1 diabetes in humans.
Treatment of NOD mice with end-stage disease by injection of donor splenocytes
and complete Freund's adjuvant eliminates autoimmunity and permanently ...
Cited by 245 - Related articles - All 12 versions


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