- ►diabetesjournals.org D Eberlé, K Clément, D Meyre, M Sahbatou, M … - Diabetes, 2004 - Am Diabetes Assoc Sterol regulatory element–binding protein (SREBP)-1 transcription factors play a central role
in energy homeostasis by promoting glycolysis, lipogenesis, and adipogenesis. The sterol regulatory
element–binding protein gene (SREBF)-1 is a good candidate gene for obesity and ... Cited by 53 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org M Laudes, I Barroso, J Luan, MA Soos, G Yeo, A … - Diabetes, 2004 - Am Diabetes Assoc The transcription factor sterol regulatory element binding protein (SREBP)-1c is intimately involved
in the regulation of lipid and glucose metabolism. To investigate whether mutations in this gene
might contribute to insulin resistance, we screened the exons encoding the aminoterminal ... Cited by 28 - Related articles - BL Direct - All 4 versions
TK Felder, H Oberkofler, R Weitgasser, V … - International Journal of …, 2006 - nature.com The sterol regulatory element-binding protein-1c (SREBP-1c) is a transcription factor involved
in the regulation of lipid and glucose metabolism and has been implicated in the pathophysiology
of type 2 diabetes mellitus (T2DM). ... We aimed to confirm associations of the SREBF-1 ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►sinoas.com [PDF] B Védie, X Jeunemaitre, JL Mégnien, V Atger, A Simon, … - Atherosclerosis, 2001 - Elsevier Sterol-regulatory element binding proteins (SREBPs) are ubiquitous transcription factors that
regulate the genes encoding key proteins in the control of cholesterol homeostasis. We looked
for mutations or polymorphisms within the sequences of the SREBP-1a gene critical for ... Cited by 29 - Related articles - All 9 versions
- ►nih.gov AH Harding, RJF Loos, J Luan, SO'Rahilly, NJ … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis The sterol regulatory element-binding fac- tor (SREBF)-1c is a transcription
factor involved in the regulation of lipid and glucose metabolism. We have previously found evidence
that a common SREBF1c single-nucleotide polymorphism (SNP), located between exons ... Cited by 9 - Related articles - All 11 versions
H Oberkofler, N Fukushima, H Esterbauer, F … - BBA-Gene Structure and …, 2002 - Elsevier Sterol regulatory element binding proteins (SREBPs) are transcription factors that are involved
in adipogenesis and regulate the expression of genes controlling cholesterol and fatty acid
biosynthesis. Animal experiments indicate that SREBP-1a, -1c, and -2 have distinct ... Cited by 18 - Related articles - All 5 versions
C Sewter, D Berger, RV Considine, G Medina, J … - Diabetes, 2002 - Am Diabetes Assoc Sterol regulatory element binding protein (SREBP)-1 is a transcription factor with important roles
in the control of fatty acid metabolism and adipogenesis. Little information is available regarding
the expression of this molecule in human health or disease. Exposure of isolated human ... Cited by 85 - Related articles - BL Direct - All 5 versions
R Laaksonen, KM Thelen, H Päivä, J Matinheikki, R … - Atherosclerosis, 2006 - Elsevier Sterol regulatory element binding proteins-1 and -2 (SREBPs) are transcription factors controlling
lipid homeostasis in human cells. The G-allele carriers of the SREBF-1 gene C–G polymorphism
in exon 18c and coding for glycine at the protein level (G952G) have shown to associate ... Cited by 8 - Related articles - All 14 versions
- ►oxfordjournals.org F Demenais, T Kanninen, CM Lindgren, S … - Human Molecular …, 2003 - Oxford Univ Press Positional cloning is expected to identify novel susceptibility genes underlying complex
traits, but replication of genome-wide linkage scan findings has proven erratic. To improve our
ability to detect and prioritize chromosomal regions containing type 2 diabetes ... Cited by 65 - Related articles - BL Direct - All 6 versions
M Kolehmainen, H Vidal, E Alhava, MIJ Uusitupa - Obesity, 2001 - nature.com Discussion: SREBP-1c mRNA expression was lower in omental adipose tissue than in subcutaneous
depots in obese subjects before weight loss. Furthermore, the expression of SREBP-1c in obese
subjects was clearly lower than in normal weight subjects, but mRNA levels increased ... Cited by 35 - Related articles - BL Direct - All 2 versions
