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Scholar Results 1 - 10 of about 101 related to Tiikkainen: Effects of rosiglitazone and metformin on liver fat content, hepatic insulin.... (0.10 sec) 

Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, …


M Tiikkainen, AM Häkkinen, E Korsheninnikova … - Diabetes, 2004 - Am Diabetes Assoc
Both rosiglitazone and metformin increase hepatic insulin sensitivity, but their
mechanism of action has not been compared in humans. The objective of this study
was to compare the effects of rosiglitazone and metformin treatment on ...
Cited by 276 - Related articles - BL Direct - All 6 versions

A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic …


E Bugianesi, E Gentilcore, R Manini, S Natale … - American journal of gastroenterology, 2005 - interscience.wiley.com
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 269 - Related articles - All 4 versions

Effect of Rosiglitazone on Insulin Sensitivity and Body Composition in Type 2 Diabetic …


DG Carey, GJ Cowin, GJ Galloway, NP Jones, … - Obesity, 2002 - nature.com
Results: There was a significant improvement in glycemic control (glycosylated
hemoglobin -0.7 0.7%, p 0.05) and an 86% increase in insulin sensitivity in the
RSG group (glucose-disposal rate change from baseline: 17.5 14.5 mol ...
Cited by 130 - Related articles - All 3 versions

Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in …


M Bajaj, S Suraamornkul, T Pratipanawatr, LJ … - Diabetes, 2003 - Am Diabetes Assoc
The effect of pioglitazone on splanchnic glucose uptake (SGU), endogenous
glucose production (EGP), and hepatic fat content was studied in 14 type 2
diabetic patients (age 50 ± 2 years, BMI 29.4 ± 1.1 kg/m 2 , HbA 1c 7.8 ...
Cited by 165 - Related articles - BL Direct - All 4 versions

A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis


R Belfort, SA Harrison, K Brown, C Darland, J … - New England Journal of Medicine, 2006 - content.nejm.org
Methods We randomly assigned 55 patients with impaired glucose tolerance or type
2 diabetes and liver biopsy–confirmed nonalcoholic steatohepatitis to 6 months
of treatment with a hypocaloric diet (a reduction of 500 kcal per day in ...
Cited by 380 - Related articles - BL Direct - All 7 versions

Decreased plasma adiponectin concentrations are closely related to hepatic fat content and …

- endojournals.org
M Bajaj, S Suraamornkul, P Piper, LJ Hardies … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
The effect of pioglitazone (PIO) on plasma adiponectin concentration, endogenous
glucose production (EGP), and hepatic fat content (HFC) was studied in 11 type 2
diabetic patients (age, 52 ± 2 yr; body mass index, 29.6 ± 1.1 kg/m 2 ; ...
Cited by 211 - Related articles - BL Direct - All 6 versions

The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle …


AB Mayerson, RS Hundal, S Dufour, V Lebon, … - Diabetes, 2002 - Am Diabetes Assoc
We examined the effect of three months of rosiglitazone treatment (4 mg bid) on
whole-body insulin sensitivity and in vivo peripheral adipocyte insulin
sensitivity as assessed by glycerol release in microdialysis from ...
Cited by 418 - Related articles - BL Direct - All 4 versions

Metformin in the treatment of non-alcoholic steatohepatitis: a pilot open label trial


S Nair, AM Diehl, M Wiseman, GH Farr, RP … - Alimentary Pharmacology and Therapeutics, 2004 - interscience.wiley.com
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Cited by 177 - Related articles - BL Direct - All 5 versions

Metformin in the treatment of patients with non-alcoholic steatohepatitis


A Uygun, A Kadayifci, AT Isik, T Ozgurtas, S … - Alimentary Pharmacology and Therapeutics, 2004 - medscape.com
Ongoing studies and current reports have focused on the role of
hyperinsulinaemia and increased insulin resistance as major pathogenic factors
in the development of non-alcoholic steatohepatitis. [7,8] On the basis of ...
Cited by 199 - Related articles - BL Direct - All 10 versions

Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-g ligand …


BA Neuschwander-Tetri, EM Brunt, KR … - Hepatology, 2003 - interscience.wiley.com
Insulin resistance (IR) commonly is associated with nonalcoholic steatohepatitis
(NASH). To establish whether IR causes NASH, this study was undertaken to
determine if improving IR would improve the histologic features that define ...
Cited by 513 - Related articles - All 6 versions


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