E Gesina, F Tronche, P Herrera, B Duchene, … - Diabetes, 2004 - Am Diabetes Assoc To determine whether glucocorticoids are involved in pancreas development,
glucocorticoid treatment of rat pancreatic buds in vitro was combined with the
analysis of transgenic mice lacking the glucocorticoid receptor (GR) in ... Cited by 33 - Related articles - BL Direct - All 4 versions
- ►physiology.org B Blondeau, J Lesage, P Czernichow, JP … - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc In rats, poor fetal growth due to maternal food restriction during pregnancy is
associated with decreased -cell mass at birth and glucose intolerance in
adulthood. Overexposure to glucocorticoids in utero can induce intrauterine ... Cited by 52 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] CN Shen, JR Seckl, JMW Slack, D Tosh - Biochemical Journal, 2003 - pubmedcentral.nih.gov Biochem. J. (2003) 375, 41–50 (Printed in Great Britain) ... Glucocorticoids
suppress β-cell development and induce hepatic ... Chia-Ning SHEN*, Jonathan
R. SECKL†, Jonathan MW SLACK* and David TOSH* Cited by 58 - Related articles - BL Direct - All 9 versions
- ►nih.gov E Gesina, B Blondeau, A Milet, I Le Nin, B … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Beta cell development is sensitive to glucocorticoid
levels. Although direct effects of glucocorti- coids on pancreatic precursors
have been shown to control beta cell mass expansion, indirect effects of ... Cited by 8 - Related articles - BL Direct - All 7 versions
B Breant, E Gesina, B Blondeau - Horm Res, 2006 - content.karger.com Low birth weight is strongly predictive of hypertension, cardiovascular
diseases, obesity, insulin resistance and diabetes. The mechanisms by which
fetal undernutrition and, hence, low birth weight increase the risk of ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►archives-ouvertes.fr GR Reducing - Diabetologia, 2006 - hal.archives-ouvertes.fr E18 GR null/null fetuses showed smaller digestive tracts and tiny pancreata.
Massive pancreatic disorganisation and apoptosis were observed despite the
presence of all cell types. E15.5 GR null/null mutants were ... Related articles - All 4 versions
B Davani, N Portwood, G Bryzgalova, MK … - Diabetes, 2004 - Am Diabetes Assoc Glucocorticoids are diabetogenic hormones because they decrease glucose uptake,
increase hepatic glucose production, and inhibit insulin release. To study the
long-term effects of increased glucocorticoid sensitivity in β-cells, we ... Cited by 20 - Related articles - BL Direct - All 5 versions
S Gremlich, R Roduit, B Thorens - Journal of Biological Chemistry, 1997 - ASBMB GLUT2 expression is strongly decreased in glucose-unresponsive pancreatic β
cells of diabetic rodents. This decreased expression is due to circulating
factors distinct from insulin or glucose. Here we evaluated the effect of ... Cited by 67 - Related articles - BL Direct - All 6 versions
MJ Nyirenda, JR Seckl - International journal of molecular medicine, 1998 - ncbi.nlm.nih.gov There is increasing epidemiological evidence in humans which associates low
birth weight with later cardiovascular and metabolic disorders including
hypertension, insulin resistance, hyperlipidaemia and death from ischaemic ... Cited by 37 - Related articles - BL Direct - All 2 versions
- ►pubget.com [PDF] S Merezak, B Reusens, A Renard, K Goosse, … - Diabetologia, 2004 - Springer Aims/hypothesis. A maternal low-protein diet has been shown to induce an
increased susceptibility of fetal islets to cytokines, but this effect can be
avoided by maternal taurine supplementation. Here, we question whether ... Cited by 25 - Related articles - BL Direct - All 9 versions
