- ►mellitech.com [PDF] F Chimienti, S Devergnas, A Favier, M Seve - Diabetes, 2004 - Am Diabetes Assoc SLC30A8, a novel member of the zinc transporter (ZnT) family, was identified by
searching the human genomic and expressed sequence tag (EST) databases with the
amino acid sequence of all known human ZnT. The protein (369 amino acids) ... Cited by 81 - Related articles - BL Direct - All 7 versions
- ►biologists.org F Chimienti, S Devergnas, F Pattou, F Schuit … - Journal of cell science, 2006 - jcs.biologists.org Insulin-secreting pancreatic beta cells are exceptionally rich in zinc. In these
cells, zinc is required for zinc-insulin crystallization within secretory
vesicles. Secreted zinc has also been proposed to be a paracrine and ... Cited by 49 - Related articles - BL Direct - All 9 versions
- ►jbc.org T Kambe, H Narita, Y Yamaguchi-Iwai, J … - Journal of Biological Chemistry, 2002 - ASBMB Intracellular homeostasis for zinc is achieved through the coordinate regulation
of specific transporters engaged in zinc influx, efflux, and intracellular
compartmentalization. We have identified a novel mammalian zinc ... Cited by 114 - Related articles - BL Direct - All 5 versions
M Seve, F Chimienti, S Devergnas, A Favier - BMC genomics, 2004 - biomedcentral.com From genomic databanks analysis, we identified the full-length sequences of two
novel SLC30 genes, SLC30A8 and SLC30A10, extending the SLC30 family to ten
members. We used an expressed sequence tag (EST) data mining strategy to ... Cited by 38 - Related articles - Cached - All 9 versions
F Chimienti, A Favier, M Seve - Biometals, 2005 - Springer The zinc content in the pancreatic beta cell is among the highest of the body.
Zinc appears to be an important metal for insulin-secreting cells as insulin is
stored inside secretory vesicles as a solid hexamer bound with two Zn 2+ ... Cited by 37 - Related articles - BL Direct - All 5 versions
L Huang, CP Kirschke, J Gitschier - Journal of Biological Chemistry, 2002 - ASBMB We describe ZnT6, a new member of the CDF (cation diffusion facilitator) family
of heavy metal transporters. The humanZNT6 gene was mapped at 2p21–22, while
the mouseZnt6 was localized to chromosome 17. Overexpression of ZnT6 in ... Cited by 115 - Related articles - BL Direct - All 6 versions
CP Kirschke, L Huang - Journal of Biological Chemistry, 2003 - ASBMB ZnT7, a novel member of the zinc transporter (ZnT) family, was identified by
searching the expressed sequence tag (EST) databases with the amino acid
sequence of ZnT1. Like the other ZnT proteins, the protein (387 amino ... Cited by 113 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org K Inoue, K Matsuda, M Itoh, H Kawaguchi, H … - Human Molecular Genetics, 2002 - Oxford Univ Press We isolated a mammalian gene whose expression transiently increased in response
to intimal denudation of rabbit aorta. It was identical to a gene encoding a
zinc transporter, ZNT5, reported very recently by others. Mice deficient ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►usda.gov [PDF] RD Palmiter, L Huang - Pflügers Archiv European Journal of Physiology, 2004 - Springer Abstract All of the members of this family are thought to facilitate zinc efflux
from the cytoplasm either into various intracellular compartments (endosomes,
secretory granules, synaptic vesicles, Golgi apparatus, or trans- Golgi ... Cited by 121 - Related articles - BL Direct - All 11 versions
H Staiger, F Machicao, N Stefan, O Tschritter, … - PLoS One, 2007 - pubmedcentral.nih.gov Background. Type 2 diabetes arises when insulin resistance-induced compensatory
insulin secretion exhausts. Insulin resistance and/or b-cell dysfunction result
from the interaction of environmental factors (high-caloric diet and ... Cited by 47 - Related articles - All 5 versions
