- ►diabetesjournals.org C Guidry, R Feist, R Morris, CW Hardwick - Diabetes, 2004 - Am Diabetes Assoc Müller cells, the principal glia of the retina, generate tractional forces in response to IGF-I and
platelet-derived growth factor and are present in diabetic fibro-vascular scar tissues causing
traction retinal detachment. While diabetes-associated increases in vitreous IGFs have ... Cited by 23 - Related articles - BL Direct - All 4 versions
- ►iovs.org C Guidry, KM Bradley, JL King - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Müller cells were isolated from papain-DNase–digested human retina. Cell identity
and changes in cell phenotype were confirmed by immunodetection of glial fibrillary acidic protein
(GFAP), cellular retinaldehyde-binding protein (CRALBP), vimentin, and -smooth muscle ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►iovs.org [PDF] C Hardwick, R Feist, R Morris, M White, D … - … ophthalmology & visual …, 1997 - ARVO Purpose. To examine the levels of Miiller cell contraction-stimulating activity in human vitre-
ous, correlate these levels with clinical presentation, and identify the causative growth
factors. Methods. Human vitreous was collected from patients undergoing pars plana ... Cited by 25 - Related articles - BL Direct - All 3 versions
- ►iovs.org JL King, C Guidry - Investigative ophthalmology & visual science, 2004 - ARVO PURPOSE. Müller cells are consistently identified in diabetic fibrocontractive ocular tissues
and, in response to insulin-like growth factor I, generate tractional forces of the type that cause
retinal detachment. Recent studies suggest that diabetes-associated increases in vitreous ... Cited by 6 - Related articles - BL Direct - All 3 versions
- ►iovs.org [PDF] C Guidry - Investigative ophthalmology & visual science, 1997 - ARVO Purpose. Toassess theability ofretinal Muller cells togenerate tractional forces during
dediffer- entiation in culture and to assess their responsiveness to contraction-stimulating growth
fac- tors. Methods. Muller cells were isolated from papain-DNase-digested porcine retina. ... Cited by 34 - Related articles - BL Direct - All 3 versions
C Guidry - Progress in retinal and eye research, 2005 - Elsevier Despite advances in surgical management of fibrocontractive retinal disorders, proliferative vitreoretinopathy
(PVR) and proliferative diabetic retinopathy (PDR) remain major causes of blindness and there
is still considerable uncertainty about the origins and roles of the cell types involved. ... Cited by 29 - Related articles - All 4 versions
[CITATION] Guidry C. Muller cell production of insulin-like growth factor-binding proteins in vitro …
J Spranger, J Bühnen, V Jansen, M Krieg, R … - … and metabolic research …, 2000 - ncbi.nlm.nih.gov Increased intraocular levels of angiogenic growth factors such as insulin-like growth factor I
(IGF-I) have been demonstrated in proliferative diabetic retinopathy (PDR). It is unclear whether
increased leakage of the blood retina barrier or local synthesis primarily determine ... Cited by 18 - Related articles
SJ Sramek, IH Wallow, TS Stevens, TM Nork - Ophthalmology, 1989 - ncbi.nlm.nih.gov The frequency and extent of immunostaining for actin, fibronectin (FN), and glial fibrillary acidic
protein (GFAP) were determined in 37 preretinal membranes (PRMs) obtained at vitrectomy
from 35 patients with proliferative diabetic retinopathy (PDR) (n = 16), proliferative ... Cited by 38 - Related articles - All 4 versions
EL Fletcher, JA Phipps, JL Wilkinson- … - Clinical & experimental …, 2005 - ncbi.nlm.nih.gov Diabetic retinopathy is the leading cause of blindness in those of working age. It is well known
that the retinal vasculature is altered during diabetes. More recently, it has emerged that neuronal
and glial dysfunction occurs in those with diabetes. Current research is directed at ... Cited by 23 - Related articles - All 4 versions
