J Seufert - Diabetes, 2004 - Am Diabetes Assoc The hormone leptin is secreted from white adipocytes, and serum levels of leptin
correlate with adipose tissue mass. Leptin was first described to act on the
satiety center in the hypothalamus through specific receptors (leptin ... Cited by 97 - Related articles - BL Direct - All 5 versions
- ►pnas.org J Seufert, TJ Kieffer, JF Habener - Proceedings of the National Academy of Sciences, 1999 - National Acad Sciences Leptin controls feeding behavior and insulin secretion from pancreatic β-cells.
Insulin stimulates the production of leptin, thereby establishing an
adipoinsular axis. Earlier we identified leptin receptors on pancreatic ... Cited by 109 - Related articles - BL Direct - All 9 versions
- ►endojournals.org J Seufert, TJ Kieffer, CA Leech, GG Holz, W … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc Previously we demonstrated the expression of the long form of the leptin
receptor in rodent pancreatic ß-cells and an inhibition of insulin secretion by
leptin via activation of ATP-sensitive potassium channels. Here we examine ... Cited by 209 - Related articles - BL Direct - All 17 versions
B AhreÂn, PJ Havel - Endokrinologie II - medizin.uni-halle.de Bo AhreÂn and Peter J. Havel Leptin and Insulin Secretion Leptin was the first
described of a growing number of hormones produced by adipose tissue (Rajala and
Scherer, 2003; Havel, 2004). Leptin is integrally involved in the ... Related articles
- ►fasebj.org RB Ceddia, HA Koistinen, JR Zierath, G … - The FASEB Journal, 2002 - FASEB Obesity is commonly associated with the development of insulin resistance and
diabetes in humans and rodents. Insulin resistance and diabetes are observed in
lipoatrophic individuals or rodent models of lipoatrophy. Here we focus on ... Cited by 140 - Related articles - BL Direct - All 4 versions
- ►physiology.org BO Ahren, PJ Havel - … Journal of Physiology- Regulatory, Integrative and …, 1999 - Am Physiological Soc The effect of leptin on insulin secretion is controversial due to conflicting
results in the literature. In the present study, we incubated insulin-producing
rat insulinoma INS-1 cells for 60 min and examined the effects of ... Cited by 39 - Related articles - BL Direct - All 4 versions
JA Cases, I Gabriely, XH Ma, XM Yang, T … - Diabetes, 2001 - Am Diabetes Assoc The demonstration of leptin receptors on the pancreatic β-cells suggests the
possibility of direct actions of leptin on insulin secretion. In vitro studies
on islets or perfused pancreas and β-cell lines produced inconsistent ... Cited by 71 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org [PDF] MH Vickers, S Reddy, BA Ikenasio, BH Breier - Journal of Endocrinology, 2001 - Soc Endocrinology Obesity and its related disorders are the most prevalent health problems in the
Western world. Using the para- digm of fetal programming we developed a rodent
model which displays the phenotype of obesity and metabolic disorders ... Cited by 67 - Related articles - BL Direct - All 6 versions
- ►physiology.org TJ Kieffer, JF Habener - American Journal of Physiology- Endocrinology And …, 2000 - Am Physiological Soc The prevalence of obesity and related diabetes mellitus is increasing worldwide.
Here we review evidence for the existence of an adipoinsular axis, a dual
hormonal feedback loop involving the hormones insulin and leptin produced ... Cited by 223 - Related articles - BL Direct - All 3 versions
