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Scholar Results 1 - 10 of about 101 related to Cox: Linkage of calpain 10 to type 2 diabetes. (0.10 sec) 

Linkage of calpain 10 to type 2 diabetes

- diabetesjournals.org
NJ Cox, MG Hayes, CA Roe, T Tsuchiya, GI … - Diabetes, 2004 - Am Diabetes Assoc
The follow-up studies to the original report of association of variation at
calpain 10 (CAPN10) with type 2 diabetes in the Mexican-American population of
Starr County, Texas, encompass a broad range of science. There are ...
Cited by 47 - Related articles - BL Direct - All 5 versions

A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel …


YP Zhou, S Sreenan, CY Pan, KPM Currie, VP … - Metabolism, 2003 - Elsevier
Genetic variation in the gene for a cytosolic cysteine protease, calpain-10,
increases the susceptibility to type 2 diabetes apparently by altering levels of
gene expression. In view of the importance of altered [beta ]-cell function ...
Cited by 42 - Related articles - BL Direct - All 8 versions

Evidence that an Isoform of Calpain-10 is a Regulator of Exocytosis in Pancreatic {beta}- …

- endojournals.org
C Marshall, GA Hitman, CJ Partridge, A Clark … - Molecular Endocrinology, 2005 - Endocrine Soc
Calpain-10 (CAPN10) is the first type 2 diabetes susceptibility gene to be
identified through a genome scan, with polymorphisms being associated with
altered CAPN10 expression. Functional data have been hitherto elusive, but ...
Cited by 49 - Related articles - All 5 versions

钙蛋白酶-10 基因与胰岛素抵抗


汝颖, 王佑民, 王长江 - 国外医学: 内分泌学分册, 2003 - cqvip.com
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Related articles - All 3 versions

Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 …

- nih.gov
MN Weedon, PEH Schwarz, Y Horikawa, N … - The American Journal of Human Genetics, 2003 - Elsevier
Variation in the calpain-10 gene (CAPN10 [MIM 605286]) was recently linked and
associated with type 2 diabetes mellitus (T2DM) susceptibility (Horikawa et al.
2000). The initial linkage of T2DM to chromosome 2 was found in a ...
Cited by 127 - Related articles - BL Direct - All 7 versions

Variation in the calpain-10 gene is associated with elevated triglyceride levels and …

- endojournals.org
E Carlsson, J Fredriksson, L Groop, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc
Our aim was to investigate the possible role of the type 2 diabetes
susceptibility gene CAPN10 in obesity. A case control study consisting of 235
obese Swedish subjects [body mass index, 40 (35–45) kg/m 2 ] and 235 ...
Cited by 41 - Related articles - BL Direct - All 4 versions

Capn10, a candidate gene responsible for type 2 diabetes mellitus in the OLETF rat


Y Muramatsu, Y Taniguchi, H Kose, K … - IUBMB life, 2003 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative …

- nih.gov
Y Song, T Niu, JAE Manson, DJ Kwiatkowski, … - The American Journal of Human Genetics, 2004 - Elsevier
The calpain-10 gene (CAPN10) on chromosome 2q37.3 was the first candidate gene
for type 2 diabetes (T2D) identified through a genomewide screen and positional
cloning. One polymorphism (UCSNP-43: G→A) and a specific haplotype ...
Cited by 77 - Related articles - BL Direct - All 9 versions

[PDF] Calpain facilitates GLUT4 vesicle translocation during insulin-stimulated glucose uptake in …


DS Paul, AW Harmon, CP Winston, YM Patel - Biochemical Journal, 2003 - bj.portlandpress.com
Calpains are a family of non-lysosomal cysteine proteases. Recent studies have
identified a member of the calpain family of proteases, calpain 10, as a
putative diabetes-susceptibility gene that may be involved in the ...
Cited by 48 - Related articles - View as HTML - BL Direct - All 10 versions

Calpain-10 gene polymorphisms and type 2 diabetes in West Africans: the Africa America …


Y Chen, R Kittles, J Zhou, G Chen, A … - Annals of epidemiology, 2005 - Elsevier
A total of 347 diabetic subjects and 148 unaffected controls from four ethnic
groups in two West African countries were enrolled in this study. After
genotyping three SNPs of CAPN10 and one SNP from CYP19, the allele, ...
Cited by 11 - Related articles - All 7 versions


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