- ►diabetesjournals.org HF Gu, A Abulaiti, CG Östenson, K Humphreys, C … - Diabetes, 2004 - Am Diabetes Assoc Adiponectin (APM1) is an adipocyte-derived peptide. The APM1 gene is located on chromosome
3q27 and linked to type 2 diabetes. In patients with type 2 diabetes, the adiponectin level in plasma
is decreased in comparison to healthy subjects. To identify genetic defects of the APM1 ... Cited by 92 - Related articles - BL Direct - All 5 versions
C Populaire, Y Mori, C Dina, F Vasseur, M Vaxillaire, T … - Diabetologia, 2003 - Springer The number of hospitalised infections in first year of life were also analysed for interaction with
gender. This showed no difference between boys and girls (p=0.94). To our knowledge this is
the first study indicating a gender difference in the impact of neonatal infections on the ... Cited by 37 - Related articles - All 3 versions
- ►oxfordjournals.org F Vasseur, N Helbecque, C Dina, S Lobbens, … - Human Molecular …, 2002 - Oxford Univ Press Adiponectin (ACRP30), an adipocyte-secreted protein encoded by the APM1 gene, is known
to modulate insulin sensitivity and glucose homeostasis, those effects protecting obese mice
from diabetes. Plasma adiponectin levels correlate well with insulin sensitivity in humans, ... Cited by 295 - Related articles - BL Direct - All 7 versions
V de Courten… - Diabetes, 2005 - Am Diabetes Assoc Adiponectin is an abundant adipose tissue-derived protein with important metabolic effects. Plasma
adiponectin levels are decreased in obese individuals, and low adiponectin levels predict insulin
resistance and type 2 diabetes. Two variants in the adiponectin gene ACDC have been ... Cited by 39 - Related articles - All 6 versions
- ►diabetesjournals.org C Menzaghi, T Ercolino, R Di Paola, AH Berg, JH … - Diabetes, 2002 - Am Diabetes Assoc Adiponectin is a protein secreted by adipocytes that modulates insulin action. To assess whether
variants of this gene contribute to the prevalence of insulin resistance in Caucasians, we genotyped
413 nondiabetic individuals for two single nucleotide polymorphisms (SNPs) at this locus. ... Cited by 259 - Related articles - BL Direct - All 5 versions
F Gibson, P Froguel - Diabetes, 2004 - Am Diabetes Assoc We have carried out a detailed reexamination of the genetics of the APM1 locus and its contribution
to the genetic basis of type 2 diabetes susceptibility in the French Caucasian population. The
G allele of single nucleotide polymorphism −11426 in the APM1 promoter showed ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org FB Hu, A Doria, T Li, JB Meigs, S Liu, A Memisoglu, D … - Diabetes, 2004 - Am Diabetes Assoc Previous data suggesting that polymorphisms in the adiponectin gene were associated with
insulin resistance or type 2 diabetes have been inconsistent. We assessed the relationship between
five common haplotype-tagging single nucleotide polymorphisms (SNPs) in the ... Cited by 76 - Related articles - BL Direct - All 5 versions
O Ukkola, E Ravussin, P Jacobson, L Sjöström, C … - Metabolism, 2003 - Elsevier Adiponectin (also called AdipoQ, gelatin-binding protein 28, Acrp30) DNA sequence variants
were determined in 96 unrelated female subjects with severe obesity (mean body mass index
[BMI], 42.3 kg/m 2 ) and in 96 non-obese female controls (mean BMI, 23.0 kg/m 2 ) from ... Cited by 51 - Related articles - All 12 versions
M Stumvoll, O Tschritter, A Fritsche, H Staiger, W Renn, … - Diabetes, 2002 - Am Diabetes Assoc The adipocyte-derived hormone adiponectin seems to protect from insulin resistance, a key factor
in the pathogenesis of type 2 diabetes. Genome-wide scans have mapped a susceptibility locus
for type 2 diabetes and the metabolic syndrome to chromosome 3q27, where the ... Cited by 271 - Related articles - BL Direct - All 5 versions
F Fumeron, R Aubert, A Siddiq, D Betoulle, F Péan, S … - Diabetes, 2004 - Am Diabetes Assoc The plasma concentration of the adipocyte-derived peptide adiponectin is decreased in patients
with obesity and type 2 diabetes. The adiponectin gene is located on chromosome 3q27, where
a diabetes susceptibility locus has been mapped. Adiponectin gene polymorphisms ... Cited by 84 - Related articles - BL Direct - All 6 versions
