KR Steffensen, JÅ Gustafsson - Diabetes, 2004 - Am Diabetes Assoc The nuclear receptors liver X receptor (LXR)α and LXRβ are sensors of
cholesterol metabolism and lipid biosynthesis. They have recently been found to
be regulators of inflammatory cytokines, suppressors of hepatic glucose ... Cited by 106 - Related articles - BL Direct - All 4 versions
- ►nih.gov BA Laffitte, LC Chao, J Li, R Walczak, S … - Proceedings of the National Academy of Sciences of …, 2003 - National Acad Sciences The control of lipid and glucose metabolism is closely linked. The nuclear
receptors liver X receptor (LXR)α and LXRβ have been implicated in gene
expression linked to lipid homeostasis; however, their role in glucose ... Cited by 225 - Related articles - BL Direct - All 10 versions
G Cao, Y Liang, CL Broderick, BA Oldham, TP … - Journal of Biological Chemistry, 2003 - ASBMB The oxysterol receptors LXR (liver X receptor)-α and LXRβ are nuclear
receptors that play a key role in regulation of cholesterol and fatty acid
metabolism. We found that LXRs also play a significant role in glucose ... Cited by 160 - Related articles - BL Direct - All 4 versions
AM Efanov, S Sewing, K Bokvist, J Gromada - Diabetes, 2004 - Am Diabetes Assoc Liver X receptors (LXRs) α and β, transcription factors of a nuclear hormone
receptor family, are expressed in pancreatic islets as well as
glucagon-secreting and insulin-secreting cell lines. Culture of pancreatic ... Cited by 60 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org TM Stulnig, KR Steffensen, H Gao, M Reimers … - Molecular pharmacology, 2002 - ASPET Liver X receptor (LXR) and LXR are nuclear oxysterol receptors whose biological
function has so far been elucidated only with respect to cholesterol and lipid
metabolism. To expose novel biological roles for LXRs, we performed ... Cited by 88 - Related articles - BL Direct - All 3 versions
- ►shouxi.net I Gerin, VW Dolinsky, JG Shackman, RT … - Journal of Biological Chemistry, 2005 - ASBMB Liver X receptors (LXR) α and β are nuclear oxysterol receptors with
established roles in cholesterol, lipid, and carbohydrate metabolism. Although
LXRs have been extensively studied in liver and macrophages, the importance ... Cited by 55 - Related articles - All 7 versions
- ►endojournals.org LK Juvet, SM Andresen, GU Schuster, KT … - Molecular Endocrinology, 2003 - Endocrine Soc Considerable progress has been made during the past years in understanding the
molecular mechanisms of adipogenesis. Three classes of transcription factors
that directly influence adipogenesis have so far been identified. These are ... Cited by 88 - Related articles - BL Direct - All 4 versions
- ►endojournals.org H Zitzer, W Wente, MB Brenner, S Sewing, K … - Endocrinology, 2006 - Endocrine Soc Liver X receptors (LXR and LXRß) regulate glucose and lipid metabolism.
Pancreatic ß-cells and INS-1E insulinoma cells express only the LXRß isoform.
Activation of LXRß with the synthetic agonist T0901317 increased glucose- ... Cited by 23 - Related articles - BL Direct - All 4 versions
LJ Millatt, V Bocher, JC Fruchart, B Staels - BBA-Molecular and Cell Biology of Lipids, 2003 - Elsevier The liver X receptors (LXRα and LXRβ) are nuclear receptor transcription
factors that are activated by certain oxysterol derivatives of cholesterol. As
such, LXR activity may be up-regulated by cellular lipid loading or dietary ... Cited by 49 - Related articles - All 6 versions
