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The biology of peroxisome proliferator-activated receptors


P Ferré - Diabetes, 2004 - Am Diabetes Assoc
Peroxisome proliferator-activated receptors (PPARs) are transcription factors belonging to the
superfamily of nuclear receptors. Three isoforms (α, δ, and γ) have been described. They act
on DNA response elements as heterodimers with the nuclear retinoic acid receptor. Their ...
Cited by 251 - Related articles - BL Direct - All 7 versions

Be fit or be sick: peroxisome proliferator-activated receptors are down the road

- endojournals.org
B Desvergne, L Michalik, W Wahli - Molecular Endocrinology, 2004 - Endocrine Soc
Investigating metabolism by unveiling the functions of the nuclear receptors peroxisome
proliferator-activated receptors (PPARs) in the numerous intricate pathways ensuring energy
homeostasis and fitness has been extremely rewarding. Major lines of research were ...
Cited by 130 - Related articles - BL Direct - All 8 versions

PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth


ED Rosen, BM Spiegelman - Journal of Biological Chemistry, 2001 - ASBMB
The peroxisome proliferator-activated receptors (PPARs) 1 comprise an important subfamily
of the nuclear hormone receptor (NHR) superfamily. These ligand-activated transcription factors
have been intensively studied for more than a decade and have been implicated in such ...
Cited by 626 - Related articles - BL Direct - All 8 versions

[PDF] 인슐린 저항성과 PPARγ


차봉수, 박세은 - 210.101.116.17
Page 1. 당뇨병 제 30 권 제 5 호, 2006 종 설 - 317 - 인슐린 저항성과 PPARγ 연세대학교 의과대학
내과학교실 차봉수․박세은 Insulin Resistance and PPARγ Bong Soo Cha, Se Eun Park
Department of Internal Medicine, Yonsei University College of Medicine ...
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PPARs and the complex journey to obesity


RM Evans - The Keio Journal of Medicine, 2004 - J-STAGE
I would like to thank all of you for staying through this long day of lectures, as I get to have the
last word. I wish to thank Drs. Hayashi and Kizaki for their kind remarks and for keeping everyone
on time and to also thank Dr. Miyashita, my co-recipient of this award for staying until the ...
Cited by 514 - Related articles - BL Direct - All 8 versions

[CITATION] PPAR gamma and glucose homeostasis


RK Semple, SO'Rahilly - Insulin resistance: insulin action and its disturbances in …, 2005
Cited by 1 - Related articles

PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance


M Guerre-Millo, C Rouault, P Poulain, J André, V … - Diabetes, 2001 - Am Diabetes Assoc
Peroxisome proliferator–activated receptor (PPAR)-α controls the expression of genes involved
in lipid metabolism. PPAR-α furthermore participates to maintain blood glucose during acute
metabolic stress, as shown in PPAR-α–null mice, which develop severe hypoglycemia ...
Cited by 136 - Related articles - BL Direct - All 6 versions

Effect of tesaglitazar, a dual PPARα/γ agonist, on glucose and lipid abnormalities in …


BJ Goldstein, J Rosenstock, D Anzalone, … - Current Medical …, 2006 - informahealthcare.com
Objective: The Glucose and Lipid Assessment in Diabetes (GLAD) trial examined the dose-response
relationship of the dual peroxisome proliferator- activated receptor (PPAR) α/γ agonist tesaglitazar
in type 2 diabetic patients. Study design: GLAD was a 12-week, multicenter, international, ...
Cited by 29 - Related articles - BL Direct - All 4 versions

[PDF] Peroxisome proliferator activated receptor ligands for the treatment of insulin …


D Patsouris, M Muller, S Kersten - Current Opinion in Investigational …, 2004 - biomedcentral.com
Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription
factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these
receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current ...
Cited by 17 - Related articles - View as HTML - BL Direct - All 4 versions

Novel genes regulated by the insulin sensitizer rosiglitazone during adipocyte …

- diabetesjournals.org
T Albrektsen, KS Frederiksen, WE Holmes, E Boel, K … - Diabetes, 2002 - Am Diabetes Assoc
Thiazolidinediones (TZDs) are a new class of compounds that improve insulin sensitivity in type
2 diabetic patients as well as in rodent models of this disease. These compounds act as ligands
for a member of the nuclear hormone receptor superfamily, peroxisome proliferator– ...
Cited by 47 - Related articles - BL Direct - All 5 versions


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