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Scholar Results 1 - 10 of about 101 related to Duchen: Roles of mitochondria in health and disease. (0.24 sec) 

Roles of mitochondria in health and disease

- diabetesjournals.org
MR Duchen - Diabetes, 2004 - Am Diabetes Assoc
Mitochondria play a central role in cell life and cell death. An increasing
number of studies place mitochondrial dysfunction at the heart of disease, most
notably in the heart and the central nervous system. In this article, I ...
Cited by 142 - Related articles - BL Direct - All 5 versions

Mitochondria and Ca2+ in cell physiology and pathophysiology


MR Duchen - Cell Calcium, 2000 - Elsevier
There is now a consensus that mitochondria take up and accumulate Ca 2+ during
physiological [Ca 2+ ] c signalling. This contribution will consider some of the
functional consequences of mitochondrial Ca 2+ uptake for cell physiology ...
Cited by 153 - Related articles - BL Direct - All 4 versions

A historical review of cellular calcium handling, with emphasis on mitochondria


NEL Saris, E Carafoli - Biochemistry (Moscow), 2005 - Springer
This article is based on a lecture presented at a recent Calcium Symposium [1].
Both authors have had long experience in the field. Saris was introduced to mito
chondriology by Britton Chance at the Reeves Johnson Foundation, University ...
Cited by 57 - Related articles - All 5 versions

Mitochondria and calcium: from cell signalling to cell death

- nih.gov
MR Duchen - The Journal of Physiology, 2000 - Physiological Soc
While a pathway for Ca 2+ accumulation into mitochondria has long been
established, its functional significance is only now becoming clear in relation
to cell physiology and pathophysiology. The observation that mitochondria ...
Cited by 412 - Related articles - BL Direct - All 7 versions

Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a …

- jbc.org
PA Antinozzi, H Ishihara, CB Newgard, CB … - Journal of Biological Chemistry, 2002 - ASBMB
The precise metabolic steps that couple glucose catabolism to insulin secretion
in the pancreatic beta cell are incompletely understood. ATP generated from
glycolytic metabolism in the cytosol, from mitochondrial metabolism, and/or ...
Cited by 60 - Related articles - BL Direct - All 6 versions

Variances of direct genetic effects, maternal genetic effects, and cytoplasmic inheritance …

- dairy-science.org [PDF] 
LG Albuquerque, JF Keown, LD Van Vleck - Journal of Dairy Science, 1998 - dairy-science.org
Received December 2, 1996. Accepted October 6, 1997. 1 Published as Paper Number
11778 of the Journal Series, Nebraska Agricultural Research Division, University
of Nebraska, Lincoln 68583-0908. 2 Permanent address: Departamento de ...
Cited by 27 - Related articles - BL Direct - All 8 versions

Ca2+ signaling, mitochondria and cell death.


C Giorgi, A Romagnoli, P Pinton, R Rizzuto - Current molecular medicine, 2008 - ncbi.nlm.nih.gov
In the complex interplay that allows different signals to be decoded into
activation of cell death, calcium (Ca2+) plays a significant role. In all
eukaryotic cells, the cytosolic concentration of Ca2+ ions ([Ca2+]c) is ...
Cited by 25 - Related articles - BL Direct

Quantification of calcium signal transmission from sarco-endoplasmic reticulum to the …

- nih.gov
P Pacher, G Csordás, TG Schneider, G … - The Journal of Physiology, 2000 - Physiological Soc
Ca 2+ was released from the SR/ER by addition of saturating caffeine or IP 3 and
subsequently thapsigargin (Tg), an inhibitor of SR/ER Ca 2+ pumps. The amount of
Ca 2+ transmitted to the mitochondria was determined by measuring increases ...
Cited by 49 - Related articles - BL Direct - All 6 versions

[CITATION] Imaging mitochondrial function in intact cells


MR DUCHEN, A SURIN, J JACOBSON - Methods in enzymology, 2002 - cat.inist.fr
Imaging mitochondrial function in intact cells. Michael R DUCHEN, Alexander SURIN,
Jake JACOBSON Methods in enzymology 361, 353-389, Elsevier, 2002.
Cited by 68 - Related articles - BL Direct - All 2 versions

Selective role for superoxide in InsP3 receptor-mediated mitochondrial dysfunction and …

- rupress.org
M Madesh, BJ Hawkins, T Milovanova, CD … - Journal of Cell Biology, 2005 - jcb.rupress.org
Reactive oxygen species (ROS) play a divergent role in both cell survival and
cell death during ischemia/reperfusion (I/R) injury and associated inflammation.
In this study, ROS generation by activated macrophages evoked an ...
Cited by 34 - Related articles - BL Direct - All 6 versions


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