- ►diabetesjournals.org A Tarasov, J Dusonchet, F Ashcroft - Diabetes, 2004 - Am Diabetes Assoc Closure of ATP-sensitive K + channels (K ATP channels) is a key step in
glucose-stimulated insulin secretion. The precise mechanism(s) by which glucose
metabolism regulates K ATP channel activity, however, remains ... Cited by 47 - Related articles - BL Direct - All 4 versions
AP de Deux - Diabetes, 2004 - Am Diabetes Assoc Closure of ATP-sensitive K + channels (KATP channels) is a key step in
glucose-stimulated insulin secretion. The precise mechanism(s) by which glucose
metabolism regulates KATP channel activity, however, remains con- ... Related articles - All 2 versions
- ►nih.gov CW Lin, F Yan, S Shimamura, S Barg, SL … - Diabetes, 2005 - Am Diabetes Assoc ATP-sensitive K + channels (K ATP channels) of pancreatic β-cells play key
roles in glucose-stimulated insulin secretion by linking metabolic signals to
cell excitability. Membrane phosphoinositides, in particular ... Cited by 16 - Related articles - BL Direct - All 6 versions
P Tammaro, C Girard, J Molnes, PR Njølstad, … - The EMBO Journal, 2005 - pubmedcentral.nih.gov ATP-sensitive K (K ATP ) channels, comprised of pore-forming Kir6.2 and
regulatory SUR1 subunits, play a critical role in regulating insulin secretion.
Binding of ATP to Kir6.2 inhibits, whereas interaction of MgATP with SUR1 ... Cited by 35 - Related articles - All 7 versions
P Tammaro, C Girard, J Molnes… - The EMBO Journal, 2005 - ukpmc.ac.uk ATP-sensitive K (K ATP ) channels, comprised of pore-forming Kir6.2 and
regulatory SUR1 subunits, play a critical role in regulating insulin secretion.
Binding of ATP to Kir6.2 inhibits, whereas interaction of MgATP with SUR1 ... Related articles
- ►oxfordjournals.org P Proks, C Girard, FM Ashcroft - Human Molecular Genetics, 2005 - Oxford Univ Press Recent studies have shown that heterozygous mutations in KCNJ11, which encodes
Kir6.2, the pore-forming subunit of the ATP-sensitive potassium (K ATP )
channel, cause permanent neonatal diabetes either alone (R201C, R201H) or ... Cited by 33 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org AI Tarasov, CAJ Girard, FM Ashcroft - Diabetes, 2006 - Am Diabetes Assoc ATP-sensitive K + channels (K ATP channels) couple cell metabolism to electrical
activity and thereby to physiological processes such as hormone secretion,
muscle contraction, and neuronal activity. However, the mechanism by which ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►physoc.org M Dabrowski, S Trapp, FM Ashcroft - The Journal of Physiology, 2003 - Physiological Soc The pancreatic β-cell type of ATP-sensitive potassium (K ATP ) channel
(Kir6.2/SUR1) is inhibited by intracellular ATP and ADP, which bind to the
Kir6.2 subunit, and is activated by Mg-nucleotide interaction with the ... Cited by 8 - Related articles - BL Direct - All 5 versions
A Rucha, EJ Verspohl - Cell biochemistry and function, 2005 - interscience.wiley.com Heterologous desensitization is a term that describes the observation that
chronic exposure of a cell to an agonist attenuates its response to other
agonists. To characterize the cellular mechanisms that might be responsible ... Cited by 5 - Related articles - All 3 versions
