- ►diabetesjournals.org U Quast, D Stephan, S Bieger, U Russ - Diabetes, 2004 - Am Diabetes Assoc Insulin secretagogues (sulfonylureas and glinides) increase insulin secretion by
closing the ATP-sensitive K + channel (K ATP channel) in the pancreatic β-cell
membrane. K ATP channels subserve important functions also in the heart. ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►bmj.com JJ Meier, B Gallwitz, WE Schmidt, A Mugge, … - British Medical Journal, 2004 - heart.bmj.com ABSTRACT In the UGDP study, published in the 1970s, a high incidence of
cardiovascular mortality was found in patients treated with the sulfonylurea
agent tolbutamide. Impaired ischaemic preconditioning is presumed to be the ... Cited by 47 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org MM Mocanu, HL Maddock, GF Baxter, CL … - Circulation, 2001 - Am Heart Assoc Methods and Results—Rat hearts were Langendorff-perfused, subjected to 35
minutes of regional ischemia and 120 minutes of reperfusion, and assigned to 1
of the following treatment groups: (1) control; (2) IP of 2x 5 minutes each ... Cited by 95 - Related articles - BL Direct - All 8 versions
W Hueb, AH Uchida, BJ Gersh, RTB Betti, N … - Coronary artery disease, 2007 - journals.lww.com Objective: Ischemic preconditioning is an increased tolerance to myocardial
ischemia during the second of two consecutive exercise tests. ATP-sensitive K +
channel blockers, such as glinides and sulfonylurea drugs, can induce loss ... Cited by 10 - Related articles - BL Direct - All 3 versions
D Stephan, M Winkler, P Kühner, U Russ, U … - Diabetologia, 2006 - Springer Page 1. ARTICLE Selectivity of repaglinide and glibenclamide for the
pancreatic over the cardiovascular K ATP channels D. Stephan ... Cited by 14 - Related articles - BL Direct - All 3 versions
- ►canadianmedicaljournal.ca SH Simpson, SR Majumdar, RT Tsuyuki, DT … - Canadian Medical Association Journal, 2006 - canadianmedicaljournal.ca Methods: This was a retrospective, inception cohort study using administrative
data from Saskatchewan Health (1991– 1999). The 5795 subjects, identified by
their first-ever dispensation for an oral antidiabetic agent, were grouped ... Cited by 74 - Related articles - BL Direct - All 11 versions
- ►alfediam.org [PDF] JP Riveline, N Danchin, F Ledru, M Varroud- … - Diabetes and Metabolism, 2003 - Elsevier The main molecule studied is glibenclamide (GB). In vitro and in animal studies,
GB is both deleterious for ischemic preconditionning (IPC) and protective for
arrhythmia during acute ischemia. Glimepiride (GM) and gliclazide (GCZ) do ... Cited by 33 - Related articles - BL Direct - All 4 versions
FE Nielsen, TB Bodvarsdottir, A Worsaae, P … - J. Med. Chem, 2002 - pubs.acs.org 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives
were synthesized and characterized as activators of adenosine 5'-triphosphate
(ATP) sensitive potassium (K ATP ) channels in the β-cells by measuring ... Cited by 33 - Related articles - BL Direct - All 4 versions
- ►endojournals.org TM Lee, TF Chou - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc EPIDEMIOLOGICAL STUDIES HAVE shown that diabetic patients are more prone to
develop postinfarction complications (1). Moreover, diabetic patients with
ischemic heart disease have a substantially worse outcome after coronary ... Cited by 99 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org P Proks, F Reimann, N Green, F Gribble, F … - Diabetes, 2002 - Am Diabetes Assoc Sulfonylureas are widely used to treat type 2 diabetes because they stimulate
insulin secretion from pancreatic ß-cells. They primarily act by binding to the
SUR subunit of the ATP-sensitive potassium (K ATP ) channel and inducing ... Cited by 117 - Related articles - BL Direct - All 3 versions