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Scholar Results 1 - 10 of about 101 related to Kane: ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training,.... (0.08 sec) 

ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, …

- diabetesjournals.org
GC Kane, A Behfar, S Yamada, C Perez-Terzic, … - Diabetes, 2004 - Am Diabetes Assoc
Exercise training elicits a metabolic and cardiovascular response that underlies
fitness. The molecular mechanisms that orchestrate this adaptive response and
secure the wide-ranging gains of a regimented exercise program are poorly ...
Cited by 57 - Related articles - BL Direct - All 5 versions

KCNJ 11 gene knockout of the Kir 6. 2 KATP channel causes maladaptive remodeling and …

- oxfordjournals.org
GC Kane, A Behfar, RB Dyer, DF O'Cochlain, … - Human Molecular Genetics, 2006 - Oxford Univ Press
Heart failure is a growing epidemic, with systemic hypertension a major risk
factor for development of disease. However, the molecular determinants that
prevent the transition from a state of hypertensive load to that of overt ...
Cited by 39 - Related articles - BL Direct - All 7 versions

Genetic disruption of Kir6. 2, the pore-forming subunit of ATP-sensitive K+ channel, …


XK Liu, S Yamada, GC Kane, AE Alekseev, DM … - Diabetes, 2004 - Am Diabetes Assoc
Metabolic-sensing ATP-sensitive K + channels (K ATP channels) adjust membrane
excitability to match cellular energetic demand. In the heart, K ATP channel
activity has been linked to homeostatic shortening of the action potential ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Cellular remodeling in heart failure disrupts KATP channel-dependent stress tolerance


DM Hodgson, LV Zingman, GC Kane, C Perez- … - The EMBO Journal, 2003 - pubmedcentral.nih.gov
ATP-sensitive potassium (K ATP ) channels are required for maintenance of
homeostasis during the metabolically demanding adaptive response to stress.
However, in disease, the effect of cellular remodeling on K ATP channel ...
Cited by 52 - Related articles - BL Direct - All 6 versions

Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced …

- physoc.org
S Yamada, GC Kane, A Behfar, XK Liu, RB Dyer … - The Journal of physiology, 2006 - Physiological Soc
Ventricular load can precipitate development of the heart failure syndrome, yet
the molecular components that control the cardiac adaptive response to imposed
demand remain partly understood. Compromised ATP-sensitive K + (K ATP ) ...
Cited by 32 - Related articles - BL Direct - All 6 versions

Kir6. 2 is required for adaptation to stress

- nih.gov
LV Zingman, DM Hodgson, PH Bast, GC Kane, C … - Proceedings of the National Academy of Sciences, 2002 - National Acad Sciences
Reaction to stress requires feedback adaptation of cellular functions to secure
a response without distress, but the molecular order of this process is only
partially understood. Here, we report a previously unrecognized regulatory ...
Cited by 144 - Related articles - BL Direct - All 9 versions

ATP-sensitive K+ channel channel/enzyme multimer: metabolic gating in the heart

- nih.gov
AE Alekseev, DM Hodgson, AB Karger, S Park … - Journal of molecular and cellular cardiology, 2005 - Elsevier
Cardiac ATP-sensitive K + (K ATP ) channels, gated by cellular metabolism, are
formed by association of the inwardly rectifying potassium channel Kir6.2, the
potassium conducting subunit, and SUR2A, the ATP-binding cassette protein ...
Cited by 39 - Related articles - All 6 versions

Knockout of Kir6. 2 negates ischemic preconditioning-induced protection of myocardial …

- physiology.org
RJ Gumina, D Pucar, P Bast, DM Hodgson, CE … - American Journal of Physiology- Heart and Circulatory …, 2003 - Am Physiological Soc
Although ischemic preconditioning induces bioenergetic tolerance and thereby
remodels energy metabolism that is crucial for postischemic recovery of the
heart, the molecular components associated with preservation of cellular ...
Cited by 68 - Related articles - BL Direct - All 4 versions

[CITATION] Stress without distress: homeostatic role for KATP channels


LV Zingman, DM Hodgson, AE Alekseev, A … - Molecular Psychiatry, 2003 - nature.com
Jump to main content; Jump to navigation; nature.com homepage; Publications
AZ index; Browse by subject. My account; Submit manuscript; ...
Cited by 21 - Related articles - BL Direct - All 2 versions

ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel …


M Bienengraeber, TM Olson, VA Selivanov, EC … - Nature genetics, 2004 - pubmedcentral.nih.gov
Cited by 144 - Related articles - All 4 versions


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